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Interleukin-17 mediates liver progenitor cell transformation into cancer stem cells through downregulation of miR-122 被引量:1
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作者 Imène Gasmi CamiliaMachou +9 位作者 AurélieRodrigues Julien Calderaro Benoit Rousseau Arthur Brouillet Christophe Rodriguez Vanessa Demontant guillaume gricourt Alain Luciani Jean-Michel Pawlotsky Fouad Lafdil 《Cancer Biology & Medicine》 SCIE CAS CSCD 2018年第S01期14-15,共2页
Objective:Cancer stem cells(CSCs)have been the focus of several studies because oftheir involvement in cancer initiation and progression.CSCs were identified in 28%to 50%of hepatocellular carcinomas(HCCs).The origin o... Objective:Cancer stem cells(CSCs)have been the focus of several studies because oftheir involvement in cancer initiation and progression.CSCs were identified in 28%to 50%of hepatocellular carcinomas(HCCs).The origin of CSCs is still unclear,but it has been recently suggested that CSCs could originate from the transformation of liver progenitor cells(LPCs)during chronic liver inflammation. 展开更多
关键词 INTERLEUKIN-17 mediates LIVER
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