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Neck observation versus elective neck dissection in management of clinical T1/2N0 oral squamous cell carcinoma: a retrospective study of 232 patients 被引量:2
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作者 Xiangqi Liu Xiaomei Lao +4 位作者 Lizhong Liang Sien Zhang Kan Li guiqing liao Yujie Liang 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2017年第3期179-188,共10页
Objective: The management of early-stage (cT1/2N0) oral squamous cell carcinoma (OSCC) remains a controversial issue. The aim of this study was to compare the clinical outcomes of neck observation (OBS) and elective n... Objective: The management of early-stage (cT1/2N0) oral squamous cell carcinoma (OSCC) remains a controversial issue. The aim of this study was to compare the clinical outcomes of neck observation (OBS) and elective neck dissection (END) in treating patients with cT1/2N0 OSCC. Methods: A total of 232 patients with cT1/2N0 OSCC were included in this retrospective study. Of these patients, 181 were treated with END and 51 with OBS. The survival curves of 5-year overall survival (OS), disease-specific survival (DSS), and recurrence-free survival (RFS) rates were plotted using the Kaplan-Meier method for each group, and compared using the Log-rank test. Results: There was no significant difference in 5-year OS and DSS rates between END and OBS groups (OS: 89.0% vs. 88.2%, P=0.906; DSS: 92.3% vs. 92.2%, P=0.998). However, the END group had a higher 5-year RFS rate than the OBS group (90.1% vs. 76.5%, P=0.009). Patients with occult metastases in OBS group (7/51) had similar 5-year OS rate (57.1% vs. 64.1%, P=0.839) and DSS rate (71.4% vs. 74.4%, P=0.982) to those in END group (39/181). In the regional recurrence patients, the 5-year OS rate (57.1% vs. 11.1%, P=0.011) and DSS rate (71.4% vs. 22.2%, P=0.022) in OBS group (7/51) were higher than those in END group (9/181). Conclusions: The results indicated that OBS policy could obtain the same 5-year OS and DSS as END. Under close follow-up, OBS policy may be an available treatment option for patients with clinical T1/2N0 OSCC. 展开更多
关键词 Lymphatic metastasis neck dissection neck observation oral squamous cell carcinoma SURVIVAL
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下颌骨转移性成釉细胞瘤伴右颌下区淋巴结转移一例
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作者 欧发荣 廖贵清 +2 位作者 纪焕中 张深榕 苏凯 《中华口腔医学研究杂志(电子版)》 CAS 2022年第5期309-312,共4页
转移性成釉细胞瘤于2017年世界卫生组织(WHO)新分类中被划分为良性成釉细胞瘤,其易转移至肺部、颈部。本文报道1例下颌骨转移性成釉细胞瘤伴右颌下区淋巴结转移的病例,并结合相关文献分析其临床表现及预后,为临床诊治提供参考。
关键词 下颌骨 成釉细胞瘤 转移 淋巴结
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