The dissemination of cattle brucellosis in Zhejiang province of China can be attributed to the transport of cattle between cities within the province. In this paper,an n-patch dynamical model is proposed to study the ...The dissemination of cattle brucellosis in Zhejiang province of China can be attributed to the transport of cattle between cities within the province. In this paper,an n-patch dynamical model is proposed to study the effect of cattle dispersal on brucellosis spread. Theoretically,we analyze the dynamical behavior of the muti-patch model. For the 2-patch submodel,sensitivity analyses of the basic reproduction number R0 and the number of the infectious cattle in term of model parameters are carried out. By numerical analysis,it is obtained that the dispersal of susceptible cattle between patches and the centralization of infected cattle to the large scale patch can alleviate the epidemic and are in favor of the control of disease in the whole region.展开更多
Consider the heterogeneity(e.g.,heterogeneous social behaviour,heterogeneity due to different geography,contrasting contact patterns and different numbers of sexual partners etc.)of host population,in this paper,the a...Consider the heterogeneity(e.g.,heterogeneous social behaviour,heterogeneity due to different geography,contrasting contact patterns and different numbers of sexual partners etc.)of host population,in this paper,the authors propose an infection age multigroup SEIR epidemic model.The model system also incorporates the feedback variables,where the infectivity of infected individuals may depend on the infection age.In the direction of mathematical analysis of model,the basic reproduction number R_0 has been computed.The global stability of disease-free equilibrium and endemic equilibrium have been established in the term of R_(0).More precisely,for R_(0)≤1,the disease-free equilibrium is globally asymptotically stable and for R_(0)>1,they establish global stability of endemic equilibrium using some graph theoretic techniques to Lyapunov function method.By considering a numerical example,they investigate the effects of infection age and feedback on the prevalence of the disease.Their result shows that feedback parameters have different and even opposite effects on different groups.However,by choosing an appropriate value of feedback parameters,the disease could be eradicated or maintained at endemic level.Besides,the infection age of infected individuals may also change the behaviour of the disease,global stable to damped oscillations or damped oscillations to global stable.展开更多
基金supported by the National Natural Science Foundation of China under Grant（11331009,11171314,11147015,11301490） the National Youth Natural Science Foundation（11201434）+1 种基金 the Specialized Research Fund for the Doctoral Program of Higher Education（20121420130001） the Research Project Supported by Shanxi Scholarship Council of China（2013-3）
文摘The dissemination of cattle brucellosis in Zhejiang province of China can be attributed to the transport of cattle between cities within the province. In this paper,an n-patch dynamical model is proposed to study the effect of cattle dispersal on brucellosis spread. Theoretically,we analyze the dynamical behavior of the muti-patch model. For the 2-patch submodel,sensitivity analyses of the basic reproduction number R0 and the number of the infectious cattle in term of model parameters are carried out. By numerical analysis,it is obtained that the dispersal of susceptible cattle between patches and the centralization of infected cattle to the large scale patch can alleviate the epidemic and are in favor of the control of disease in the whole region.
基金supported by the National Natural Science Foundation of China(No.12022113)Henry Fok Foundation for Young Teachers,China(No.171002)+2 种基金Outstanding Young Talents Support Plan of Shanxi Province,Science and Engineering Research Board(SERB for short),India(No.ECR/2017/002786)UGC-BSR Research Start-Up-Grant,India(No.F.30-356/2017(BSR))Senior Research Fellowship from the Council of Scientific and Industrial Research(CSIR for short),India(No.09/1131(0006)/2017-EMR-I)。
文摘Consider the heterogeneity(e.g.,heterogeneous social behaviour,heterogeneity due to different geography,contrasting contact patterns and different numbers of sexual partners etc.)of host population,in this paper,the authors propose an infection age multigroup SEIR epidemic model.The model system also incorporates the feedback variables,where the infectivity of infected individuals may depend on the infection age.In the direction of mathematical analysis of model,the basic reproduction number R_0 has been computed.The global stability of disease-free equilibrium and endemic equilibrium have been established in the term of R_(0).More precisely,for R_(0)≤1,the disease-free equilibrium is globally asymptotically stable and for R_(0)>1,they establish global stability of endemic equilibrium using some graph theoretic techniques to Lyapunov function method.By considering a numerical example,they investigate the effects of infection age and feedback on the prevalence of the disease.Their result shows that feedback parameters have different and even opposite effects on different groups.However,by choosing an appropriate value of feedback parameters,the disease could be eradicated or maintained at endemic level.Besides,the infection age of infected individuals may also change the behaviour of the disease,global stable to damped oscillations or damped oscillations to global stable.
