Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen.Due to its specific structural,biological and physicochemical properties,collagen hydrol...Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen.Due to its specific structural,biological and physicochemical properties,collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field.In this review,we summarize recent advances in antioxidant collagen hydrolysates development.Initially,the preparation process of antioxidant collagen hydrolysates is introduced,including the production and separation methods.Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed.Finally,the applications of antioxidant collagen hydrolysates in biomedical domains are summarized,with critical discussions about the advantages,current limitations and challenges to be resolved in the future.展开更多
To the Editor:Postmenopausal osteoporosis is a typical bone metabolic disruption disease caused by estrogen deficiency,characterized by deteriorated bone structure,reduced bone mineral density(BMD),and thinned sclerot...To the Editor:Postmenopausal osteoporosis is a typical bone metabolic disruption disease caused by estrogen deficiency,characterized by deteriorated bone structure,reduced bone mineral density(BMD),and thinned sclerotin,which has troubled millions of menopausal women worldwide.[1]Additionally,estrogen deficiency is accompanied by oxidative stress and inflammation,thus causing the occurrence and deterioration of osteoporosis.[2]Conventional treatment options have limited efficacy and cannot meet the requirements of long-term treatment.[3]Therefore,in order to alleviate the problem of osteoporosis in human health,innovative strategies should explore the possibilities and alternatives to current ones.In this study.展开更多
基金supported by grants from the National Natural Science Foundation of China(No.52242208).
文摘Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen.Due to its specific structural,biological and physicochemical properties,collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field.In this review,we summarize recent advances in antioxidant collagen hydrolysates development.Initially,the preparation process of antioxidant collagen hydrolysates is introduced,including the production and separation methods.Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed.Finally,the applications of antioxidant collagen hydrolysates in biomedical domains are summarized,with critical discussions about the advantages,current limitations and challenges to be resolved in the future.
基金supported by grants from the Fundamental Research Funds for the Central Universities(No.JD2231)the National Natural Science Foundation of China(No.82102038).
文摘To the Editor:Postmenopausal osteoporosis is a typical bone metabolic disruption disease caused by estrogen deficiency,characterized by deteriorated bone structure,reduced bone mineral density(BMD),and thinned sclerotin,which has troubled millions of menopausal women worldwide.[1]Additionally,estrogen deficiency is accompanied by oxidative stress and inflammation,thus causing the occurrence and deterioration of osteoporosis.[2]Conventional treatment options have limited efficacy and cannot meet the requirements of long-term treatment.[3]Therefore,in order to alleviate the problem of osteoporosis in human health,innovative strategies should explore the possibilities and alternatives to current ones.In this study.
