A new type of aza-oxa macrocycles containing pyridine ring which may be used for binding of prinary ammonium cations(R-NH) were prepared from 2.6-di(bromomethyl) pyridine and appropriate diol.
Azacrown ethers with intraannutal phenolic grouch are readily prepared by thereaction of 1, 8- bis (P-tolylsulphonybono) -3, 6-dioxaoctane with 2, 6-bis (bromomethyl) -4-R-anisole (R=CH3, Cl, Br) in a two-phase system...Azacrown ethers with intraannutal phenolic grouch are readily prepared by thereaction of 1, 8- bis (P-tolylsulphonybono) -3, 6-dioxaoctane with 2, 6-bis (bromomethyl) -4-R-anisole (R=CH3, Cl, Br) in a two-phase system of aqueous lithium hydroxjde-toluene in takepresence of Bu, NI as Phase transfer catalyst.展开更多
A convenient synthetic route to a series of hydroxyl cyclic di- and tri-aza compounds was described. Condensation of 1, 3-dichloropropanol[2] with the appropriate disodium salts of N-tosylated di-and triamine in EtOH ...A convenient synthetic route to a series of hydroxyl cyclic di- and tri-aza compounds was described. Condensation of 1, 3-dichloropropanol[2] with the appropriate disodium salts of N-tosylated di-and triamine in EtOH gave the corresponding 7-, 8- and 10-membered di- and triamine cycles in reasonable yields. The tosyl groups were removed with 33%HBr-HOAc in ca.90% yields.展开更多
New diaza-crown ethers with inward-facing phenolic groups were synthesized from 2,6- his (bromQmethyl ) -- 4 -- R--aniSOle (R -- CH 3, CI ) and 3, 9 -- ditOSyl-- 6 -- oxa.-- 3, 9 --diaZaufldecane-- l,1 1-diul.
A convenient procedure was developed for the synthesis of macrocyclic polyamines containing pyridine ring by direct condensation of 2,6-di(bromomethyl) pyridine with N-tosyl polyethylene polyamines in DMF in the prese...A convenient procedure was developed for the synthesis of macrocyclic polyamines containing pyridine ring by direct condensation of 2,6-di(bromomethyl) pyridine with N-tosyl polyethylene polyamines in DMF in the presence of K2CO3 at room temperture.展开更多
文摘A new type of aza-oxa macrocycles containing pyridine ring which may be used for binding of prinary ammonium cations(R-NH) were prepared from 2.6-di(bromomethyl) pyridine and appropriate diol.
文摘Azacrown ethers with intraannutal phenolic grouch are readily prepared by thereaction of 1, 8- bis (P-tolylsulphonybono) -3, 6-dioxaoctane with 2, 6-bis (bromomethyl) -4-R-anisole (R=CH3, Cl, Br) in a two-phase system of aqueous lithium hydroxjde-toluene in takepresence of Bu, NI as Phase transfer catalyst.
文摘A convenient synthetic route to a series of hydroxyl cyclic di- and tri-aza compounds was described. Condensation of 1, 3-dichloropropanol[2] with the appropriate disodium salts of N-tosylated di-and triamine in EtOH gave the corresponding 7-, 8- and 10-membered di- and triamine cycles in reasonable yields. The tosyl groups were removed with 33%HBr-HOAc in ca.90% yields.
文摘A convenient procedure was developed for the synthesis of macrocyclic polyamines containing pyridine ring by direct condensation of 2,6-di(bromomethyl) pyridine with N-tosyl polyethylene polyamines in DMF in the presence of K2CO3 at room temperture.
