Aryl sulfonyl radical triggered cascade cyclization of phenyl-linked 1,6-enynes for the synthesis of biologically important indenes containing alkenyl C—X bonds and 10a,11-dihydro-10H-benzo[b]fluorines is presented.I...Aryl sulfonyl radical triggered cascade cyclization of phenyl-linked 1,6-enynes for the synthesis of biologically important indenes containing alkenyl C—X bonds and 10a,11-dihydro-10H-benzo[b]fluorines is presented.In these radical cascade processes,three new chemical bonds,including C—S,C—C,and C—X bonds,and three C—C bonds are formed in one step.The method is attractive and valuable due to its metal-free,mild reaction conditions,broad substrate scope and good functional group tolerance.展开更多
基金the National Natural Science Foundation of China(No.21861043)the Yunnan Fundamental Research Projects(No.2019FB016)Scientific and Technological Innovation Team of Optical Functional Materials of Yunnan Provincial Education Department forfinancial support.
文摘Aryl sulfonyl radical triggered cascade cyclization of phenyl-linked 1,6-enynes for the synthesis of biologically important indenes containing alkenyl C—X bonds and 10a,11-dihydro-10H-benzo[b]fluorines is presented.In these radical cascade processes,three new chemical bonds,including C—S,C—C,and C—X bonds,and three C—C bonds are formed in one step.The method is attractive and valuable due to its metal-free,mild reaction conditions,broad substrate scope and good functional group tolerance.
