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息肉状脉络膜血管病变患者房水中IL-8及其受体的表达 被引量:5
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作者 李臻 王少杰 +1 位作者 刘国立 简瑞 《国际眼科杂志》 CAS 北大核心 2019年第2期221-224,共4页
目的:探究息肉状脉络膜血管病变(PCV)患者房水中IL-8及其受体1、2 (CXCR1、CXCR2)的水平,并探讨其临床意义。方法:选取2016-04/2018-03本院收治的PCV患者67例作为PCV组,另选取白内障患者50例作为对照组。采用实时荧光定量PCR法检测两组... 目的:探究息肉状脉络膜血管病变(PCV)患者房水中IL-8及其受体1、2 (CXCR1、CXCR2)的水平,并探讨其临床意义。方法:选取2016-04/2018-03本院收治的PCV患者67例作为PCV组,另选取白内障患者50例作为对照组。采用实时荧光定量PCR法检测两组患者房水中IL-8、CXCR1、CXCR2 mRNA表达量,采用国际标准视力表测量所有受试者BCVA,OCT检测CMT,创建受试者工作特征曲线(ROC)分析IL-8、CXCR1、CXCR2对PCV的诊断价值;采用Logistic多因素回归分析评估PCV发生的危险因素。结果:与对照组相比,PCV组患者房水中IL-8、CXCR1、CXCR2 mRNA表达升高,BCVA降低,CMT升高(均P <0. 05)。PCV组患者房水中IL-8、CXCR1、CXCR2水平与BCVA(LogMAR)呈正相关(r=0. 438、0. 346、0. 385,均P<0. 05),与CMT呈正相关(r=0. 378、0. 606、0. 357,均P<0. 05)。IL-8、CXCR1、CXCR2、BCVA、CMT是PCV发生的危险因素。IL-8、CXCR1、CXCR2诊断PCV的ROC曲线下面积(AUC)分别为0. 882、0. 860、0. 812。结论:PCV患者房水中IL-8、CXCR1、CXCR2表达均升高,其不仅与患者BCVA和CMT相关,且与PCV的发生有关,可能成为PCV的潜在预测指标。 展开更多
关键词 息肉状脉络膜血管病变 白介素-8 白介素-8受体 临床意义
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PDR行玻璃体切除术后黄斑区视网膜血流密度的影响因素及预测模型 被引量:4
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作者 王梓伊 温舒 +1 位作者 刘国立 方静 《国际眼科杂志》 CAS 北大核心 2022年第8期1352-1356,共5页
目的:探究增生性糖尿病视网膜病变(PDR)行玻璃体切除术后黄斑区视网膜血流密度的变化及影响因素,并构建预测模型。方法:回顾性分析2019-06/2021-06于我院行玻璃体切除术治疗的PDR患者173例173眼的临床资料,根据术后黄斑区视网膜血流密... 目的:探究增生性糖尿病视网膜病变(PDR)行玻璃体切除术后黄斑区视网膜血流密度的变化及影响因素,并构建预测模型。方法:回顾性分析2019-06/2021-06于我院行玻璃体切除术治疗的PDR患者173例173眼的临床资料,根据术后黄斑区视网膜血流密度变化情况将患者分为正常组(118例118眼)和下降组(55例55眼)。比较两组患者的一般资料、术前实验室检查指标和术中情况;采用多因素Logistic回归分析影响患者术后黄斑区视网膜血流密度变化的因素;构建列线图预测模型,并评价其预测效能。结果:下降组的糖尿病病程、合并黄斑病变患者比例、血清TC、TG、LDL-C、HbA1c、血管闭塞、增生视网膜牵引患者比例明显高于正常组,HDL-C明显低于正常组(P<0.05);多因素Logistic回归分析结果显示,糖尿病病程>17a(OR=4.526)、合并黄斑病变(OR=4.983)、HbA1c>6.25%(OR=4.283)、血管闭塞(OR=5.216)、增生视网膜牵引(OR=4.765)均是导致患者术后黄斑区视网膜血流密度下降的危险因素(P<0.05);列线图预测模型的区分度和准确性较好,具有较高的预测价值。结论:糖尿病病程、合并黄斑病变、HbA1c、血管闭塞及增生视网膜牵引均与PDR行玻璃体切除术后黄斑区视网膜血流密度下降有关,了解风险因素有利于手术的决策。 展开更多
关键词 增生性糖尿病视网膜病变(PDR) 玻璃体切除术 黄斑区视网膜 血流密度 危险因素
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;our Case Reports of Endometriosis-Related Hemoperitoneum in Pregnancy 被引量:1
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作者 Fu-Mei Gao guo-li liu 《Chinese Medical Journal》 SCIE CAS CSCD 2018年第4期502-504,共3页
To the Editor: Endometriosis is a common gynecologic condition that affects approximately 10% of females of reproductive age. It is a chronic inflammatory disease that is defined by the presence of endometrial-like t... To the Editor: Endometriosis is a common gynecologic condition that affects approximately 10% of females of reproductive age. It is a chronic inflammatory disease that is defined by the presence of endometrial-like tissue outside the uterine cavity. Endometriosis commonly occurs in the peritoneum, ovaries, and rectovaginal septum, but may also be found in other abdominal or extra-abdominal sites. 展开更多
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Bounds on Higgs and top quark masses from vacuum stability(degeneracy) with gravitational contributions
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作者 Zhuang Li guo-li liu +1 位作者 Fei Wang Lin Wang 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS CSCD 2018年第9期37-44,共8页
Based on the two-loop RGE of standard model gauge, top-Yukawa as well as scalar quartic couplings with full one-loop gravitational contributions in harmonic gauge, we study the constraints on the Higgs and top quark m... Based on the two-loop RGE of standard model gauge, top-Yukawa as well as scalar quartic couplings with full one-loop gravitational contributions in harmonic gauge, we study the constraints on the Higgs and top quark mass from the requirement that the other degenerate vacua at the Planck-dominated region exists. Our numerical calculations show that nature will not develop the other degenerate vacua at the Planck-dominated region with current Higgs and top quark masses. On the other hand, requiring the existence of the other degenerate vacua at the Planck-dominated region will constrain the Higgs and top mass to lie at approximately 130 and 174 Ge V, respectively. 展开更多
关键词 gravitational contributions top-Yukawa coupling MPCP RGE
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Top rare decays t→cV in mirror twin Higgs models
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作者 Su-Ya Bie guo-li liu Wenyu Wang 《Chinese Physics C》 SCIE CAS CSCD 2021年第1期82-88,共7页
The decay t→cV(V=γ,Z,g)processes in mirror twin Higgs models with colorless top partners are studied in this paper.We report that the branchi ng ratios of these decays can strongly affect the standard model expectat... The decay t→cV(V=γ,Z,g)processes in mirror twin Higgs models with colorless top partners are studied in this paper.We report that the branchi ng ratios of these decays can strongly affect the standard model expectations in some parameter spaces and may be detectable according to the current precision electroweak measurements.Thus,constraints on the model parameters may be obtained from the branching fraction of the decay processes,which may serve as a robust detection tool for this new physics model. 展开更多
关键词 mirror twin Higgs models t→cV branching ratios
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