Application of Narrow Band Imaging Technology of Electronic Laryngoscope in the Diagnosis of Hypopharyngeal Carcinoma

Objective:To investigate the value of electronic laryngoscope combined with narrow-band imaging(NBI)in the diagnosis of early hypopharyngeal malignant tumors and precancerous lesions.From 2021 to 2022,90 patients with NBI type diphtheria and pharyngeal lesions were examined by endoscopy and endoscopy.The results showed that there was an abnormal relationship between NBI type diphtheria and pharyngeal lesions in our hospital from 2021 to 2022.Results:the sensitivity,specificity,positive predictive value and negative predictive value of NBI endoscopy in the diagnosis of oropharyngeal and hypopharyngeal malignant lesions were 98.8%,89.2%,95.5%and 97.1%,respectively.The results of NBI endoscopy were highly consistent with those of pathological examination(kappa=0.901,P<0.01).The sensitivity,specificity,positive predictive value and negative predictive value of white light endoscopy were 83.7%,86.5%,93.5%and 69.6%respectively.The results of white light endoscopy were consistent with those of pathological examination(kappa=0.657,P<0.01).NBI endoscopy is more accurate than ordinary white light endoscopy in the diagnosis of hypopharyngeal malignant lesions(especially severe dysplasia/carcinoma in situ,P<0.01)and precancerous lesions(P<0.01).There was a significant correlation between NBI classification and pathological examination results of hypopharyngeal lesions(r=0.820,P<0.01).Conclusions:NBI endoscopy can detect hypopharyngeal carcinoma more accurately than white light endoscopy;NBI typing standard can more accurately diagnose precancerous lesions and early hypopharyngeal cancer,and judge the invasion of the latter.It is of great significance for the early diagnosis and minimally invasive treatment of hypopharyngeal cancer and precancerous lesions.

基于语料库的“V+down”构式搭配分析及语义映射

本研究基于美国当代英语语料库(COCA),采用构式搭配分析法中的共现词素分析法对“V+down”构式中进入V槽的动词与该构式之间的关联强度进行分析,考察共现动词的语义聚类,从而探究该构式的语义映射。研究发现:(1)“V+down”构式多表示空间运动或消极的结果状态;(2)“V+down”构式的原型语义是“向下运动义”,通过隐喻机制将其语义从空间域映射到社会域、心理域和生理域,使该构式具有了丰富的隐喻义。该研究是对构式搭配分析法的进一步应用,对“动词+小品词”构式教学具有一定启发作用。

语料库驱动视角下汉语强化词的意义移变单位研究

意义移变单位继承并发展了扩展意义单位的理论内涵,是本世纪以来语料库语言学在意义研究方面的最新理论成果。本研究以意义移变单位为理论工具,基于国家语委现代汉语语料库对强化词"完全"进行描写,分析其典范形式和变异形式以及二者与意义之间的关系。结果显示,意义单位的确立受共选成分影响,其中语义韵起着决定作用;强化词"完全"共有四种意义移变单位,根据频数信息每个意义单位可以确立一个典范形式和多个变异形式。研究结果证明了意义移变单位理论在汉语研究领域具有适用性,同时丰富了意义移变单位的研究内涵。

Comparison of Capillary and Venous Glucose Concentrations:A Real-world Study in Patients Undergoing Fluorodeoxyglucose-positron Emission Tomography

Objective Fasting capillary blood glucose(CBG)must be measured before fluorodeoxyglucose-positron emission tomography(FDG-PET)imaging.In this study,we aimed to investigate whether a recently measured fasting venous blood glucose(VBG)concentration could be substituted for CBG.Methods This retrospective study included 520 of 1,378 patients who had undergone FDG-PET at our institution in June 2022.None of the study patients had a history of diabetes mellitus.Each study patient’s CBG was measured immediately before FDG administration,whereas the VBG(VBG<7.8 mmol/L)was measured within one week before and after PET imaging.We used Bland−Altman plots to compare the two blood glucose concentrations.Results The 520 participants(315 male,205 female;ages 13-87 years)accounted for 37.7%(520/1378)of all patients.The median CBG and VBG were 5.7 mmol/L(interquartile range,5.2-6.2 mmol/L)and 5.1 mmol/L(interquartile range,4.8-5.8 mmol/L),respectively.There was a moderate positive correlation between CBG and VBG(r=0.4370,95%CI:0.3625-0.5059,P<0.0001).Bland-Altman plots revealed that only 5.8%(30/520)of the dots exceeded the 95%limits of agreement and these were all within acceptable limits,indicating that the bias was not clinically significant.Conclusion When performing FDG-PET on patients without diabetes,a VBG of<7.8 mmol/L within the previous week may be an acceptable alternative to CBG.