A facile and environmentally friendly visible-light-induced three-component reaction of α-diazoesters,cyclic ethers and Na SCN to construct organic thiocyanates has been developed at room temperature. This reaction c...A facile and environmentally friendly visible-light-induced three-component reaction of α-diazoesters,cyclic ethers and Na SCN to construct organic thiocyanates has been developed at room temperature. This reaction could occur under photocatalyst-and additive-free conditions to afford a number of organic thiocyanates with moderate to good yield and favorable functional group tolerance.展开更多
We report on N,N-bidentate-chelation-assistedα-and β-olefinic C–H alkenylation of aryl alkenes in ethanol to afford aryl dienes/trienes with excellent regio-and stereo-selectivities.The reaction of 2-alkenyl benzyl...We report on N,N-bidentate-chelation-assistedα-and β-olefinic C–H alkenylation of aryl alkenes in ethanol to afford aryl dienes/trienes with excellent regio-and stereo-selectivities.The reaction of 2-alkenyl benzylamine and benzoic acid derived substrates proceeded through six-membered exo-cyclo-metallation and seven-membered endo-cyclometallation.The aerobic protocols feature wide functional-ity tolerance,high selectivities and yields,mild conditions and scalable preparation,and the directing group can be easily removed to afford Boc-protected amine by simple reduction.展开更多
基金supported by the program of Science and Technology International Cooperation Project of Qinghai Province (No. 2022-HZ-813)the Youth Innovation and Technology Project of High School in Shandong Province (No. 2019KJC021)+1 种基金the Natural Science Foundation of Shandong Province (No. ZR2021MB065)the National Natural Science Foundation of China (No. 31900298)。
文摘A facile and environmentally friendly visible-light-induced three-component reaction of α-diazoesters,cyclic ethers and Na SCN to construct organic thiocyanates has been developed at room temperature. This reaction could occur under photocatalyst-and additive-free conditions to afford a number of organic thiocyanates with moderate to good yield and favorable functional group tolerance.
基金We gratefully acknowledge the National Natural Science Foundation of China(NSFC)(21672048 and 81570989)Natural Science Foundation of Zhejiang Province(ZJNSF)(LY19B020006)+1 种基金Major Project of Hangzhou Health Science and Technology Plan(Z20200046)Key Subject of Stomatology in Hangzhou for financial support.
文摘We report on N,N-bidentate-chelation-assistedα-and β-olefinic C–H alkenylation of aryl alkenes in ethanol to afford aryl dienes/trienes with excellent regio-and stereo-selectivities.The reaction of 2-alkenyl benzylamine and benzoic acid derived substrates proceeded through six-membered exo-cyclo-metallation and seven-membered endo-cyclometallation.The aerobic protocols feature wide functional-ity tolerance,high selectivities and yields,mild conditions and scalable preparation,and the directing group can be easily removed to afford Boc-protected amine by simple reduction.
