Objective:Many researches have demonstrated the effects of the extreme cold ambient temperature on the risk of out-of-hospital cardiac arrest(OHCA);yet,the results have been inconsistent.We performed a meta-analysis t...Objective:Many researches have demonstrated the effects of the extreme cold ambient temperature on the risk of out-of-hospital cardiac arrest(OHCA);yet,the results have been inconsistent.We performed a meta-analysis to evaluate whether extreme cold ambient temperature is related to OHCA.Methods:We searched for time-series studies reporting associations between extreme cold ambient temperature and OHCA in PubMed,web of science and Cochrane database.Results:Six studies involving 2337403 cases of OHCA were qualified for our meta-analysis.The odds ratio(OR)of OHCA was significantly increased in extreme cold weather(defined as the 1st or 5th centile temperature year-round)compared to reference temperature(as the 25th centile temperatures or daily mean temperature with minimum risk of OHCA)(OR=1.49,95%CI 1.18-1.88).The subgroup analysis for the elderly and the female failed to detect the influence of extreme cold weather on OHCA,the ORs are 1.25(95%CI 0.89-1.75)and 1.19(95%CI 0.87-1.64),respectively.Conclusion:The risk of OHCA is significantly higher in extreme cold ambient temperatures than in reference temperature,according to a relative temperature scale with percentiles of the region-specific temperature distribution.展开更多
基金supported by the National Key Technology R&D Program(2018YFC2000301)from the Ministry of Science and Technology of China.
文摘Objective:Many researches have demonstrated the effects of the extreme cold ambient temperature on the risk of out-of-hospital cardiac arrest(OHCA);yet,the results have been inconsistent.We performed a meta-analysis to evaluate whether extreme cold ambient temperature is related to OHCA.Methods:We searched for time-series studies reporting associations between extreme cold ambient temperature and OHCA in PubMed,web of science and Cochrane database.Results:Six studies involving 2337403 cases of OHCA were qualified for our meta-analysis.The odds ratio(OR)of OHCA was significantly increased in extreme cold weather(defined as the 1st or 5th centile temperature year-round)compared to reference temperature(as the 25th centile temperatures or daily mean temperature with minimum risk of OHCA)(OR=1.49,95%CI 1.18-1.88).The subgroup analysis for the elderly and the female failed to detect the influence of extreme cold weather on OHCA,the ORs are 1.25(95%CI 0.89-1.75)and 1.19(95%CI 0.87-1.64),respectively.Conclusion:The risk of OHCA is significantly higher in extreme cold ambient temperatures than in reference temperature,according to a relative temperature scale with percentiles of the region-specific temperature distribution.
