The authors reviewed preoperative MRI and EEG findings in relation to postsurg ical outcome in 17 patients with refractory epilepsy due to tuberous sclerosis c omplex (TSC). Resecting concordant MRI (main tuber) and E...The authors reviewed preoperative MRI and EEG findings in relation to postsurg ical outcome in 17 patients with refractory epilepsy due to tuberous sclerosis c omplex (TSC). Resecting concordant MRI (main tuber) and EEG abnormalities offere d seizure freedom (8/9, 89%; median follow-up 25 months) comparable to other f ocal etiologies. Patients with nonconcordant MRI and EEG findings did less well (3/8, 38%, seizure free; p=0.027, OR=13).展开更多
Objectives: To determine prevalence of themetabolic syndrome using United Stat es Adult Treatment Panel-3 (ATP-3) guidelines in an urban Indian population. M ethods: Randomly selected adults >20 years were studied ...Objectives: To determine prevalence of themetabolic syndrome using United Stat es Adult Treatment Panel-3 (ATP-3) guidelines in an urban Indian population. M ethods: Randomly selected adults >20 years were studied using stratified samplin g. Target study sample was 1800 with population proportionate distribution (men 960, women 840). Evaluati on of anthropometric variables, blood pressure, fasting blood glucose and lipids was performed. Subjects(1123; response 62.4%) were examined, fasting blood sam ples were available in 1091(532 men, 559 women) and analysed for prevalence of m etabolic syndrome. Atherosclerosis risk factors were determined using the curren t guidelines. Metabolic syndrome was diagnosed when any three of the following w ere present: central obesity, raised triglycerides ≥150 mg/dl (≥1.7 mmol/l), l ow high density lipoprotein (HDL) cholesterol, blood pressure ≥130/≥85mm Hg, and diabetes or fasting glucose >110 mg/dl (>6.1 mmol/l). Intergroup comparisons were performed using t test or chi square test. Results: Metabolic syndrome w as present in 345 (31.6%) subjects; prevalencewas 122 (22.9%) in men and 223 ( 39.9%) in women(p< 0.001); the age adjusted prevalence was 24.9%, 18.4%in me n and 30.9%in women. There was a significant age related increase in its preva lence(Mantel Haenzel χ2 for trend p< 0.05). Prevalence of components of metabo lic syndrome in men and women was: central obesity (waist, men>102 cm, women>88 cm) in 116 (25.6%) and 246 (44.0%); low HDL cholesterol(men<40 mg/dl,<1.0 mmol /l), women< 50 mg/dl,<1.3 mmol/l) in 292 (54.9%) and 504(90.2%); high triglyce rides ≥150 mg/dl(≥1.7 mmol/l) in 172 (32.3%) and 160 (28.6%); and impaired f asting glucose or diabetes in 90(16.9%) and 90 (16.1%). The prevalence of phys ical inactivity, hypertension, hypercholesterolemia(≥200 mg/dl, ≥5.2 mmol/l) a nd high LDL cholesterol (≥130 mg/dl, ≥3.4 mmol/l) was greater in the metabolic syndrome group in both men and women (p< 0.05). Conclusions: There is a high pr evalence of metabolic syndrome in an urban Indian population. Focus of cardiovas cular prevention should be at this high risk group.展开更多
Mucocele of the appendix is a thin-walled dilated appendix filled with mucus. It occurs secondary to chronic obstruction of the appendiceal lumen because of a range of pathologies. Cystadenomas in children are exceedi...Mucocele of the appendix is a thin-walled dilated appendix filled with mucus. It occurs secondary to chronic obstruction of the appendiceal lumen because of a range of pathologies. Cystadenomas in children are exceedingly rare and most frequently of ovarian origin. A mucous cystadenoma of the appendix in a 10- year-old boy with chronic abdominal pain is presented.展开更多
文摘The authors reviewed preoperative MRI and EEG findings in relation to postsurg ical outcome in 17 patients with refractory epilepsy due to tuberous sclerosis c omplex (TSC). Resecting concordant MRI (main tuber) and EEG abnormalities offere d seizure freedom (8/9, 89%; median follow-up 25 months) comparable to other f ocal etiologies. Patients with nonconcordant MRI and EEG findings did less well (3/8, 38%, seizure free; p=0.027, OR=13).
文摘Objectives: To determine prevalence of themetabolic syndrome using United Stat es Adult Treatment Panel-3 (ATP-3) guidelines in an urban Indian population. M ethods: Randomly selected adults >20 years were studied using stratified samplin g. Target study sample was 1800 with population proportionate distribution (men 960, women 840). Evaluati on of anthropometric variables, blood pressure, fasting blood glucose and lipids was performed. Subjects(1123; response 62.4%) were examined, fasting blood sam ples were available in 1091(532 men, 559 women) and analysed for prevalence of m etabolic syndrome. Atherosclerosis risk factors were determined using the curren t guidelines. Metabolic syndrome was diagnosed when any three of the following w ere present: central obesity, raised triglycerides ≥150 mg/dl (≥1.7 mmol/l), l ow high density lipoprotein (HDL) cholesterol, blood pressure ≥130/≥85mm Hg, and diabetes or fasting glucose >110 mg/dl (>6.1 mmol/l). Intergroup comparisons were performed using t test or chi square test. Results: Metabolic syndrome w as present in 345 (31.6%) subjects; prevalencewas 122 (22.9%) in men and 223 ( 39.9%) in women(p< 0.001); the age adjusted prevalence was 24.9%, 18.4%in me n and 30.9%in women. There was a significant age related increase in its preva lence(Mantel Haenzel χ2 for trend p< 0.05). Prevalence of components of metabo lic syndrome in men and women was: central obesity (waist, men>102 cm, women>88 cm) in 116 (25.6%) and 246 (44.0%); low HDL cholesterol(men<40 mg/dl,<1.0 mmol /l), women< 50 mg/dl,<1.3 mmol/l) in 292 (54.9%) and 504(90.2%); high triglyce rides ≥150 mg/dl(≥1.7 mmol/l) in 172 (32.3%) and 160 (28.6%); and impaired f asting glucose or diabetes in 90(16.9%) and 90 (16.1%). The prevalence of phys ical inactivity, hypertension, hypercholesterolemia(≥200 mg/dl, ≥5.2 mmol/l) a nd high LDL cholesterol (≥130 mg/dl, ≥3.4 mmol/l) was greater in the metabolic syndrome group in both men and women (p< 0.05). Conclusions: There is a high pr evalence of metabolic syndrome in an urban Indian population. Focus of cardiovas cular prevention should be at this high risk group.
文摘Mucocele of the appendix is a thin-walled dilated appendix filled with mucus. It occurs secondary to chronic obstruction of the appendiceal lumen because of a range of pathologies. Cystadenomas in children are exceedingly rare and most frequently of ovarian origin. A mucous cystadenoma of the appendix in a 10- year-old boy with chronic abdominal pain is presented.
