The three main components of the media layer of the aorta are elastic fibers,collagen fibers and smooth muscle cells(SMC).[1]This layer’s elastic properties are major determinants of its biomechanics in health and di...The three main components of the media layer of the aorta are elastic fibers,collagen fibers and smooth muscle cells(SMC).[1]This layer’s elastic properties are major determinants of its biomechanics in health and disease states.[2,3]Age-related changes in such elastic properties are associated with altered hemodynamic parameters,such as systolic hypertension,[4,5]and end-organ damage,[6,7]and are thought to result from changes of its main components.展开更多
Sheehan’s Syndrome (SS) occurs as a result of ischemic pituitary necrosis due to severe post-partum hemorrhage. We report a 41-year-old woman with a history of severe postpartum hemorrhage 18 years prior to presentat...Sheehan’s Syndrome (SS) occurs as a result of ischemic pituitary necrosis due to severe post-partum hemorrhage. We report a 41-year-old woman with a history of severe postpartum hemorrhage 18 years prior to presentation. During this period of time, she experienced severe fatigue. Three months prior to being admitted to our hospital, the patient started to notice alopecia, generalized edema and cognitive impairment. After proper investigation, laboratory tests and clinical findings indicated panhypopituitarism. In addition to neuroimaging and past medical history, SS was diagnosed and treatment started. We emphasize the importance of thorough investigation, further diagnosis and management of this condition (especially in third world countries), since SS is a neurological and endocrinological emergency and potentially life threatening.展开更多
文摘The three main components of the media layer of the aorta are elastic fibers,collagen fibers and smooth muscle cells(SMC).[1]This layer’s elastic properties are major determinants of its biomechanics in health and disease states.[2,3]Age-related changes in such elastic properties are associated with altered hemodynamic parameters,such as systolic hypertension,[4,5]and end-organ damage,[6,7]and are thought to result from changes of its main components.
文摘Sheehan’s Syndrome (SS) occurs as a result of ischemic pituitary necrosis due to severe post-partum hemorrhage. We report a 41-year-old woman with a history of severe postpartum hemorrhage 18 years prior to presentation. During this period of time, she experienced severe fatigue. Three months prior to being admitted to our hospital, the patient started to notice alopecia, generalized edema and cognitive impairment. After proper investigation, laboratory tests and clinical findings indicated panhypopituitarism. In addition to neuroimaging and past medical history, SS was diagnosed and treatment started. We emphasize the importance of thorough investigation, further diagnosis and management of this condition (especially in third world countries), since SS is a neurological and endocrinological emergency and potentially life threatening.
