Objective The purpose of the present study was to investigate the association between cardiorespiratory fitness(CRF)measured as peak oxygen uptake(VO_(2peak),expressed in mL/min)and body mass index(BMI)in a large coho...Objective The purpose of the present study was to investigate the association between cardiorespiratory fitness(CRF)measured as peak oxygen uptake(VO_(2peak),expressed in mL/min)and body mass index(BMI)in a large cohort of apparently healthy subjects.Methods BMI and VO_(2peak)were measured in a cross-sectional study of 8470 apparently healthy adults.VO_(2peak)(mL/min)was determined by an incremental cycle ergometer test to exhaustion.Linear regression analyses were performed to identify predictors of CRF.Results There was no difference in CRF between adults with a normal weight(BMI between 18.5-24.9 kg/m^(2))and those who were overweight(BMI 25.0-29.9 kg/m^(2)).Subjects who were underweight(BMI<18.5 kg/m^(2))as well as females who were obese(BMI≥30.0 kg/m^(2))showed a reduced CRF compared to the normal and overweight groups.Age,height,and gender were significant predictors of CRF(R^(2)=0.467,P<0.0001);BMI did not add significantly to this relationship.Conclusion Our findings indicate that BMI was not associated with CRF in addition to age,height,and gender.In subjects with a BMI<18.5 kg/m^(2),CRF was lower compared to subjects with a BMI between 18.5 and 29.9 kg/m^(2).In obese subjects,CRF was only lower in females compared to females with a BMI between 18.5 and 29.9 kg/m^(2).Correcting CRF for BMI may be beneficial for subjects with a low BMI,and females with a BMI≥30.0 kg/m^(2).The outcome of this study might help to improve the interpretation of exercise testing results in individuals with a low or high BMI.展开更多
文摘Objective The purpose of the present study was to investigate the association between cardiorespiratory fitness(CRF)measured as peak oxygen uptake(VO_(2peak),expressed in mL/min)and body mass index(BMI)in a large cohort of apparently healthy subjects.Methods BMI and VO_(2peak)were measured in a cross-sectional study of 8470 apparently healthy adults.VO_(2peak)(mL/min)was determined by an incremental cycle ergometer test to exhaustion.Linear regression analyses were performed to identify predictors of CRF.Results There was no difference in CRF between adults with a normal weight(BMI between 18.5-24.9 kg/m^(2))and those who were overweight(BMI 25.0-29.9 kg/m^(2)).Subjects who were underweight(BMI<18.5 kg/m^(2))as well as females who were obese(BMI≥30.0 kg/m^(2))showed a reduced CRF compared to the normal and overweight groups.Age,height,and gender were significant predictors of CRF(R^(2)=0.467,P<0.0001);BMI did not add significantly to this relationship.Conclusion Our findings indicate that BMI was not associated with CRF in addition to age,height,and gender.In subjects with a BMI<18.5 kg/m^(2),CRF was lower compared to subjects with a BMI between 18.5 and 29.9 kg/m^(2).In obese subjects,CRF was only lower in females compared to females with a BMI between 18.5 and 29.9 kg/m^(2).Correcting CRF for BMI may be beneficial for subjects with a low BMI,and females with a BMI≥30.0 kg/m^(2).The outcome of this study might help to improve the interpretation of exercise testing results in individuals with a low or high BMI.