Ionic liquid [Et3NH]Cl-FeCl3/CuCl was synthesized by mixing [Et3NH]Cl, anhydrous FeCl3 and anhydrous CuCl, and the desulfurization activity of this ionic liquid was tested. It exhibited remarkable ability in effective...Ionic liquid [Et3NH]Cl-FeCl3/CuCl was synthesized by mixing [Et3NH]Cl, anhydrous FeCl3 and anhydrous CuCl, and the desulfurization activity of this ionic liquid was tested. It exhibited remarkable ability in effective desulfurization of model gasoline(thiophene in n-octane) and fluid catalytic cracking(FCC) gasoline, and the sulfur removal of thiophene in model oil(V(IL):V(oil)=0.08) could reach 93.9% in 50 min at 50 ℃. Low-sulfur(﹤10 μg/g) FCC gasoline could be obtained after three extraction runs at an ionic liquid/oil volume ratio of 0.1, with the yield of FCC gasoline reaching 94.3%. The ionic liquid could be recycled 5 times with merely a slight decrease in activity.展开更多
目的测定扩张型心肌病(DCM)心衰患者血清可溶性ST2(sST2)及半乳凝集素(gal-3)水平,探讨其在扩张型心肌病心衰中的应用价值及临床意义。方法采用横断面调查研究,收集首都医科大学附属北京安贞医院心血管内科2017年6月至12月住院的扩张型...目的测定扩张型心肌病(DCM)心衰患者血清可溶性ST2(sST2)及半乳凝集素(gal-3)水平,探讨其在扩张型心肌病心衰中的应用价值及临床意义。方法采用横断面调查研究,收集首都医科大学附属北京安贞医院心血管内科2017年6月至12月住院的扩张型心肌病心力衰竭患者60例作为疾病组,收集冠状动脉粥样硬化性心脏病(CHD)性心力衰竭患者52例作为疾病对照,健康体检患者70名作为健康对照组。将DCM患者按纽约心脏病协会(New York Heart Association,NYHA)心功能分级,心功能Ⅰ~Ⅱ级组18例(男/女为11/7),心功能Ⅲ~Ⅳ级组42例(男/女为32/10)。sST2采用酶联免疫法进行测定,gal-3采用化学发光法进行测定。采用单因素方差分析,非参数检验以及Spearman直线相关分析等统计学方法进行分析。结果DCM组与健康对照组比较,血清sST2水平显著升高[21.23(14.59,25.29)ng/ml vs 14.59(12.78,17.16)ng/ml,标准化H=4.645,调整后P<0.001],血清gal-3水平也显著增高[13.50(10.48,19.68)μg/L vs 10.05(8.25,12.80)μg/L,标准化H=4.266,调整后P<0.001]。DCM组与CHD组相比,血清gal-3水平明显升高[13.50(10.48,19.68)μg/L vs 11.00(8.65,13.58)μg/L,标准化H=-2.715,调整后P=0.020]。sST2在心功能Ⅲ~Ⅳ级组较Ⅰ~Ⅱ级组显著升高[22.54(16.82,26.78)ng/ml vs 12.24(9.22,17.79)ng/ml,Z=2.613,P=0.009]。Spearman相关分析显示,sST2与左心室射血分数(LVFE)呈负相关(r=-0.647,P<0.01),与左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)呈正相关(r=0.393,r=0.462,均P<0.01),与B-型尿钠肽(BNP)、gal-3呈正相关(r=0.320,r=0.331,均P<0.05);gal-3与超敏肌钙蛋白I(hs-TnI)、BNP呈正相关(r=406,r=0.401,均P≤0.01),与估算的肾小球滤过率(eGFR)呈负相关(r=-0.326,P<0.05)。sST2诊断DCM心衰的ROC曲线下面积为0.745,(95% CI:0.652~0.838,P<0.001),其Cut-off值为21.00 ng/ml,在此Cut-off值下的敏感度为51.9%,特异度为95.7%;gal-3诊断DCM心衰的ROC曲线下面积为(0.720,95% CI:0.627~0.812,P<0.001),其Cut-off值为13.15 μg/L,Cut-off值下的敏感度为53.7%,特异度为85.7%;分别与BNP、hs-TnI联合应用后诊断效果明显提高,敏感度均增加至95.3%。结论扩张型心肌病心衰患者血清sST2与gal-3水平均显著升高,其中sST2水平与心功能恶化程度显著相关,而且与左心室重构有一定的相关性,二者诊断DCM心衰的价值虽不及BNP,但sST2不受年龄、体重指数和肾功能损害的影响,联合应用可显著提高诊断效能。展开更多
Let A :=(A_1, A_2) be a pair of expansive dilations and φ : R^n×R^m×[0, ∞) → [0, ∞) an anisotropic product Musielak-Orlicz function. In this article, we introduce the anisotropic product Musielak-Orlicz ...Let A :=(A_1, A_2) be a pair of expansive dilations and φ : R^n×R^m×[0, ∞) → [0, ∞) an anisotropic product Musielak-Orlicz function. In this article, we introduce the anisotropic product Musielak-Orlicz Hardy space H~φ_A(R^n× R^m) via the anisotropic Lusin-area function and establish its atomic characterization, the g-function characterization, the g_λ~*-function characterization and the discrete wavelet characterization via first giving out an anisotropic product Peetre inequality of Musielak-Orlicz type. Moreover, we prove that finite atomic decomposition norm on a dense subspace of H~φ_A(R^n× R^m) is equivalent to the standard infinite atomic decomposition norm. As an application, we show that, for a given admissible triplet(φ, q, s), if T is a sublinear operator and maps all(φ, q, s)-atoms into uniformly bounded elements of some quasi-Banach spaces B, then T uniquely extends to a bounded sublinear operator from H~φ_A(R^n× R^m) to B. Another application is that we obtain the boundedness of anisotropic product singular integral operators from H~φ_A(R^n× R^m) to L~φ(R^n× R^m)and from H~φ_A(R^n×R^m) to itself, whose kernels are adapted to the action of A. The results of this article essentially extend the existing results for weighted product Hardy spaces on R^n× R^m and are new even for classical product Orlicz-Hardy spaces.展开更多
基金supported by the National Natural Science Foundation of Shanxi Educational Committee (07JK384)the Whole Innovation of Science and Technology Project Plan of Shanxi Province (2012KTD01-01-04)the Graduate Innovation Project of Northwest University (YZZ13029)
文摘Ionic liquid [Et3NH]Cl-FeCl3/CuCl was synthesized by mixing [Et3NH]Cl, anhydrous FeCl3 and anhydrous CuCl, and the desulfurization activity of this ionic liquid was tested. It exhibited remarkable ability in effective desulfurization of model gasoline(thiophene in n-octane) and fluid catalytic cracking(FCC) gasoline, and the sulfur removal of thiophene in model oil(V(IL):V(oil)=0.08) could reach 93.9% in 50 min at 50 ℃. Low-sulfur(﹤10 μg/g) FCC gasoline could be obtained after three extraction runs at an ionic liquid/oil volume ratio of 0.1, with the yield of FCC gasoline reaching 94.3%. The ionic liquid could be recycled 5 times with merely a slight decrease in activity.
文摘目的测定扩张型心肌病(DCM)心衰患者血清可溶性ST2(sST2)及半乳凝集素(gal-3)水平,探讨其在扩张型心肌病心衰中的应用价值及临床意义。方法采用横断面调查研究,收集首都医科大学附属北京安贞医院心血管内科2017年6月至12月住院的扩张型心肌病心力衰竭患者60例作为疾病组,收集冠状动脉粥样硬化性心脏病(CHD)性心力衰竭患者52例作为疾病对照,健康体检患者70名作为健康对照组。将DCM患者按纽约心脏病协会(New York Heart Association,NYHA)心功能分级,心功能Ⅰ~Ⅱ级组18例(男/女为11/7),心功能Ⅲ~Ⅳ级组42例(男/女为32/10)。sST2采用酶联免疫法进行测定,gal-3采用化学发光法进行测定。采用单因素方差分析,非参数检验以及Spearman直线相关分析等统计学方法进行分析。结果DCM组与健康对照组比较,血清sST2水平显著升高[21.23(14.59,25.29)ng/ml vs 14.59(12.78,17.16)ng/ml,标准化H=4.645,调整后P<0.001],血清gal-3水平也显著增高[13.50(10.48,19.68)μg/L vs 10.05(8.25,12.80)μg/L,标准化H=4.266,调整后P<0.001]。DCM组与CHD组相比,血清gal-3水平明显升高[13.50(10.48,19.68)μg/L vs 11.00(8.65,13.58)μg/L,标准化H=-2.715,调整后P=0.020]。sST2在心功能Ⅲ~Ⅳ级组较Ⅰ~Ⅱ级组显著升高[22.54(16.82,26.78)ng/ml vs 12.24(9.22,17.79)ng/ml,Z=2.613,P=0.009]。Spearman相关分析显示,sST2与左心室射血分数(LVFE)呈负相关(r=-0.647,P<0.01),与左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)呈正相关(r=0.393,r=0.462,均P<0.01),与B-型尿钠肽(BNP)、gal-3呈正相关(r=0.320,r=0.331,均P<0.05);gal-3与超敏肌钙蛋白I(hs-TnI)、BNP呈正相关(r=406,r=0.401,均P≤0.01),与估算的肾小球滤过率(eGFR)呈负相关(r=-0.326,P<0.05)。sST2诊断DCM心衰的ROC曲线下面积为0.745,(95% CI:0.652~0.838,P<0.001),其Cut-off值为21.00 ng/ml,在此Cut-off值下的敏感度为51.9%,特异度为95.7%;gal-3诊断DCM心衰的ROC曲线下面积为(0.720,95% CI:0.627~0.812,P<0.001),其Cut-off值为13.15 μg/L,Cut-off值下的敏感度为53.7%,特异度为85.7%;分别与BNP、hs-TnI联合应用后诊断效果明显提高,敏感度均增加至95.3%。结论扩张型心肌病心衰患者血清sST2与gal-3水平均显著升高,其中sST2水平与心功能恶化程度显著相关,而且与左心室重构有一定的相关性,二者诊断DCM心衰的价值虽不及BNP,但sST2不受年龄、体重指数和肾功能损害的影响,联合应用可显著提高诊断效能。
基金supported by National Natural Science Foundation of China (Grant Nos. 11671414, 11271091, 11471040, 11461065, 11661075, 11571039 and 11671185)
文摘Let A :=(A_1, A_2) be a pair of expansive dilations and φ : R^n×R^m×[0, ∞) → [0, ∞) an anisotropic product Musielak-Orlicz function. In this article, we introduce the anisotropic product Musielak-Orlicz Hardy space H~φ_A(R^n× R^m) via the anisotropic Lusin-area function and establish its atomic characterization, the g-function characterization, the g_λ~*-function characterization and the discrete wavelet characterization via first giving out an anisotropic product Peetre inequality of Musielak-Orlicz type. Moreover, we prove that finite atomic decomposition norm on a dense subspace of H~φ_A(R^n× R^m) is equivalent to the standard infinite atomic decomposition norm. As an application, we show that, for a given admissible triplet(φ, q, s), if T is a sublinear operator and maps all(φ, q, s)-atoms into uniformly bounded elements of some quasi-Banach spaces B, then T uniquely extends to a bounded sublinear operator from H~φ_A(R^n× R^m) to B. Another application is that we obtain the boundedness of anisotropic product singular integral operators from H~φ_A(R^n× R^m) to L~φ(R^n× R^m)and from H~φ_A(R^n×R^m) to itself, whose kernels are adapted to the action of A. The results of this article essentially extend the existing results for weighted product Hardy spaces on R^n× R^m and are new even for classical product Orlicz-Hardy spaces.
