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哮喘-慢阻肺重叠综合征患者外周血Th17和Treg细胞水平表达与肺功能的关系研究 被引量:18
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作者 夏清 薛珉 +4 位作者 张亚娟 洪伟俊 赵华 余苏云 俞婷 《现代检验医学杂志》 CAS 2020年第2期104-107,共4页
目的分析哮喘-慢阻肺重叠综合征(ACOS)患者辅助性T细胞17(Th17)和调节性T细胞(Treg)表达水平,及其与肺功能的相关性。方法采用流式细胞术检测60例ACOS患者(ACOS组)、60例哮喘患者(哮喘组)和60例慢性阻塞性肺疾病患者(COPD组)外周血Th17... 目的分析哮喘-慢阻肺重叠综合征(ACOS)患者辅助性T细胞17(Th17)和调节性T细胞(Treg)表达水平,及其与肺功能的相关性。方法采用流式细胞术检测60例ACOS患者(ACOS组)、60例哮喘患者(哮喘组)和60例慢性阻塞性肺疾病患者(COPD组)外周血Th17和Treg细胞的表达,比较分析其与肺功能指标的关系。结果与哮喘组比较,COPD组、ACOS组外周血CD4+细胞中Th17细胞表达及Th17/Treg比例明显升高,而Treg细胞表达明显下降,差异均有统计学意义(F=15.36~36.61,均P<0.05);与COPD组比较,ACOS组外周血CD4+细胞中Th17细胞表达及Th17/Treg比例明显升高,而Treg细胞表达明显下降,差异有统计学意义(F=36.61,21.18,15.26, P<0.05)。ACOS组患者FVC%pred,FEV1%pred和FEV1/FVC明显低于哮喘组,差异均有统计学意义(F=7.36,11.36,9.68,P<0.05),但FVC%pred与COPD组患者比较,差异无统计意义(t=0.52,P>0.05)。ACOS患者外周血Th17和h17/Treg表达与FVC%pred,FEV1%pred和FEV1/FVC呈显著负相关(r=-0.502^-0.407,均P<0.05)。Treg与FVC%pred,FEV1%pred和EV1/FVC呈显著正相关(r=0.019~0.033,均P<0.05)。结论ACOS患者外周血Th17和Treg细胞表达异常,存在Th17/Treg比例失衡,且与肺功能下降密切相关。 展开更多
关键词 哮喘-慢阻肺重叠综合征 辅助性T细胞17 调节性T细胞 免疫失衡 相关
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Novel error resilient tag estimation for RFID system in interference scenarios 被引量:2
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作者 WANG Shuai hong wei-jun +1 位作者 PENG Biao LI Shu-fang 《The Journal of China Universities of Posts and Telecommunications》 EI CSCD 2013年第4期116-121,共6页
In a radio frequency identification (RFID) system, the backscattered signal is small and prone to interference. The performance of RFID tag identification in interference scenarios is degraded compared to that in er... In a radio frequency identification (RFID) system, the backscattered signal is small and prone to interference. The performance of RFID tag identification in interference scenarios is degraded compared to that in error-free scenarios. In this paper, a novel Mahalanobis distance estimate (MDE) method is proposed to jointly estimate the number of tags and packet error rate (PER). The MDE method is error resilient owing to its ability to achieve a stable estimation when interference is impairing the observed information. The proposed method achieves significantly enhanced accuracy over existing methods by taking all the information and correlations among the observed results into account. The MDE method improves the estimate performance based on efficient decorrelation and classification of the observed information. Moreover, the performance of the PER estimate is analyzed both in theory and through simulations. It can be concluded from the analysis that the estimated PER is unbiased and variance-bounded. Simulations show that the proposed estimate outperforms the previous proposals in terms of accuracy and stability, which makes it suitable for application in interference scenarios. 展开更多
关键词 RFID tag estimate PER estimate
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Quantitative spectrum occupancy evaluation in China: based on a large scale concurrent spectrum measurement
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作者 YIN Liang YIN Si-xing +3 位作者 WANG Shuai ZHANG Er-qing hong wei-jun LI Shu-fang 《The Journal of China Universities of Posts and Telecommunications》 EI CSCD 2012年第3期122-128,共7页
Due to the usable frequency becomes more and more crowed, dynamic spectrum access (DSA) is a new hope to solve this problem. However, DSA in China requires a quantitative analysis of the current spectrum utilization... Due to the usable frequency becomes more and more crowed, dynamic spectrum access (DSA) is a new hope to solve this problem. However, DSA in China requires a quantitative analysis of the current spectrum utilization in frequency, temporal and spatial domains. In order to free the precious spectrum, spectrum regulation organizations must have a clear, detailed, up-to-date understanding of where, how and by whom spectrum is currently being used--such data is essential to sound policy decisions in the context of cognitive radio (CR). In this paper, a concurrent spectrum occupancy measurement in south China was conducted to evaluate the practical spectrum occupancy with a digital wideband receiver covering from 20 MHz to 3 GHz. We also propose systemic spectrum measurement methodology, matrix format data storage, duty cycle (DC) evaluation metric and data mining process which can be a guideline for other researchers when they conduct the similar experiments. Quantitative analysis and characterization of the 4 different measurement locations are evaluated to promote the popularization of CR application in China. And a uniform Beta distribution channel occupancy model is also validated using real-scene measurement data. The experimental results demonstrate that there is a significant scope for license-exemption use of the released spectrum using CR technology. 展开更多
关键词 cognitive radio spectrum measurement spectrum occupancy duty cycle Beta distribution
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