慢性鼻-鼻窦炎(chronic rhinosinusitis,CRS)是鼻腔及鼻窦黏膜的慢性炎症,包括慢性鼻-鼻窦炎不伴鼻息肉(chronic rhinosinusitis without nasal polyps,CRSsNP)和慢性鼻-鼻窦炎伴鼻息肉(chronic rhinosinusitis with nasal polyps,CRSw...慢性鼻-鼻窦炎(chronic rhinosinusitis,CRS)是鼻腔及鼻窦黏膜的慢性炎症,包括慢性鼻-鼻窦炎不伴鼻息肉(chronic rhinosinusitis without nasal polyps,CRSsNP)和慢性鼻-鼻窦炎伴鼻息肉(chronic rhinosinusitis with nasal polyps,CRSwNP)。中医治疗CRS主要包括:辨证论治、专方验方、中成药、针灸、耳穴贴压、中药鼻腔雾化和中药鼻腔冲洗、穴位按摩等;西医治疗主要包括糖皮质激素、抗生素、抗过敏药物、黏液溶解促排剂、手术治疗等。中西医结合治疗是目前治疗CRS的重要手段,但存在以下问题:相关临床文献较少,尚无临床指南,且中医药治疗CRS的作用机制还不明确。今后,需要行多中心、大样本的临床研究,进一步深入探讨中医药治疗CRS的作用机制,为中西医结合治疗CRS提供科学依据。展开更多
As an important herbaceous plant, Scutellaria baicalensis Georgi(Chinese skullcap) is geographically widespread and commonly used throughout the world. In the Chinese medicine market, S. baicalensis has been divided i...As an important herbaceous plant, Scutellaria baicalensis Georgi(Chinese skullcap) is geographically widespread and commonly used throughout the world. In the Chinese medicine market, S. baicalensis has been divided into two primary types, "Ku Qin"(WXR) and "Tiao Qin"(TST). Moreover, TST is also divided into different grades according to the diameter of roots. To explore the distribution patterns of the contents of five biologically activate ingredients(FBAI), we used six-year-old cultivated S. baicalensis and analyzed its growth characteristics as well as the quality difference among different types and diameters in roots. Throughout the entire root, we discovered that contents of the FBAI all initially increased and subsequently decreased from the top to the bottom of the roots. The baicalin content of WXR was less than that of TST. On the contrary, the contents of baicalein, wogonin, and oroxylin A in WXR were up to about two times higher than that in TST. We also found that the 0 to 40 cm part of the S. baicalensis root possessed about 87% of the root biomass and about 92% of the contents of the active ingredients.展开更多
文摘慢性鼻-鼻窦炎(chronic rhinosinusitis,CRS)是鼻腔及鼻窦黏膜的慢性炎症,包括慢性鼻-鼻窦炎不伴鼻息肉(chronic rhinosinusitis without nasal polyps,CRSsNP)和慢性鼻-鼻窦炎伴鼻息肉(chronic rhinosinusitis with nasal polyps,CRSwNP)。中医治疗CRS主要包括:辨证论治、专方验方、中成药、针灸、耳穴贴压、中药鼻腔雾化和中药鼻腔冲洗、穴位按摩等;西医治疗主要包括糖皮质激素、抗生素、抗过敏药物、黏液溶解促排剂、手术治疗等。中西医结合治疗是目前治疗CRS的重要手段,但存在以下问题:相关临床文献较少,尚无临床指南,且中医药治疗CRS的作用机制还不明确。今后,需要行多中心、大样本的临床研究,进一步深入探讨中医药治疗CRS的作用机制,为中西医结合治疗CRS提供科学依据。
基金supported by the National Sci-tech Support Plan(No.2011BAI07B04 537/03430)the Beijing Municipal Agriculture Demonstration Project(No.20120615)
文摘As an important herbaceous plant, Scutellaria baicalensis Georgi(Chinese skullcap) is geographically widespread and commonly used throughout the world. In the Chinese medicine market, S. baicalensis has been divided into two primary types, "Ku Qin"(WXR) and "Tiao Qin"(TST). Moreover, TST is also divided into different grades according to the diameter of roots. To explore the distribution patterns of the contents of five biologically activate ingredients(FBAI), we used six-year-old cultivated S. baicalensis and analyzed its growth characteristics as well as the quality difference among different types and diameters in roots. Throughout the entire root, we discovered that contents of the FBAI all initially increased and subsequently decreased from the top to the bottom of the roots. The baicalin content of WXR was less than that of TST. On the contrary, the contents of baicalein, wogonin, and oroxylin A in WXR were up to about two times higher than that in TST. We also found that the 0 to 40 cm part of the S. baicalensis root possessed about 87% of the root biomass and about 92% of the contents of the active ingredients.
