Scrub typhus is an acute febrile vector-borne zoonotic disease caused by the obligate intracellular growth bacterium Orientia tsutsugamushi(Ot).Mites are the primary vectors and rodents play a pivotal role in the tran...Scrub typhus is an acute febrile vector-borne zoonotic disease caused by the obligate intracellular growth bacterium Orientia tsutsugamushi(Ot).Mites are the primary vectors and rodents play a pivotal role in the transmission of scrub typhus.Due to the climate warming,increased human activity and other factors,cases of scrub typhus have been increased sharply during the past decade in China,especially in the northern China.To understand the incidence trend,epidemic pattern,clinical sign,diagnosis and therapy of this diseases as well as genotype evolution of Orientia tsutsugamushi,we summarized and analyzed the current knowledge of scrub typhus in China from 2010 to 2020.The data indicated that the dominate genotypes of scrub typhus in China were Karp,Kato and Gilliam.Although the disease was distributed national wide,Yunnan,Guangzhou and Fujian showed the highest incidence rate.The main vector of scrub typhus in southwest,middle east and southeast of China appeared a geographic preference respectively.Seasonal timing,age and occupation were the key factors that relate to the peak incidence of scrub typhus.Notably,farmer was the occupation with the highest risk of Ot infection.Further study on the epidemic characteristics,risk factors,diagnosis and treatments of scrub typhus will be of benefit to a comprehensive guideline for prevention and control of this ancient disease.展开更多
Objective:To study the in vitro virucidal activity of 9 extracts of traditional Chinese herbal medicine(the water extracts of Evodia lepta,Clausena lansium,Clerodendrum cyrtophyllum,Callicarpa nudiflora,Nauclea offici...Objective:To study the in vitro virucidal activity of 9 extracts of traditional Chinese herbal medicine(the water extracts of Evodia lepta,Clausena lansium,Clerodendrum cyrtophyllum,Callicarpa nudiflora,Nauclea officinalis and Elaeagnus gonyanthes,the alcohol extracts of Nauclea officinalis,Elaeagnus gonyanthes and Zanthoxylumarmatum)on human respiratory syncytial virus(HRSV).Methods:The cytotoxic effect of the extracts on cells was evaluated by a cell viability assay using the CCK-8 method,a concentration of the extracts with cell viability greater than 50%was selected for the follow-up anti-HRSV effect assay,the 50%effective concentration(EC50)was assessed by an in vitro cell infection model.Results:The EC50s of the water extract from Clerodendrum cyrtophyllum,Callicarpa nudiflora and Elaeagnus gonyanthes were 0.05 mg/mL,0.03 mg/mL and 0.05 mg/mL,and the therapeutic index(TI)of them were 18.60,21.67 and 56.80 respectively.Conclusion:The water extracts of Clerodendrum cyrtophyllum,Callicarpa nudiflora and Elaeagnus gonyanthes possess the activity of anti-HRSV virus.展开更多
We present a novel protocol for deterministic secure quantum communication by using the four-qubit clusterstate as quantum channel.It is shown that two legitimate users can directly transmit the secret messages based ...We present a novel protocol for deterministic secure quantum communication by using the four-qubit clusterstate as quantum channel.It is shown that two legitimate users can directly transmit the secret messages based on Bell-basis measurements and classical communication.The present protocol makes use of the ideas of block transmission anddecoy particle checking technique.It has a high capacity as each cluster state can carry two bits of information,and hasa high intrinsic efficiency because almost all the instances except the decoy checking particles (its number is negligible)are useful.Furthermore,this protocol is feasible with present-day technique.展开更多
We propose two schemes for quantum secure direct communication (QSDC) and deterministic securequantum communication (DSQC) over collective dephasing noisy channel.In our schemes,four special two-qubit statesare used a...We propose two schemes for quantum secure direct communication (QSDC) and deterministic securequantum communication (DSQC) over collective dephasing noisy channel.In our schemes,four special two-qubit statesare used as the quantum channel.Since these states are unchanged through the collective dephasing noisy channel,the effect of the channel noise can be perfectly overcome.Simultaneously,the security against some usual attacks canbe ensured by utilizing the various checking procedures.Furthermore,these two schemes are feasible with present-daytechnique.展开更多
We propose a scheme for sharing an arbitrary unknown two-qubit state among three parties by using afour-qubit cluster-class state and a Bell state as a quantum channel With a quantum controlled phase gate (QCPG)operat...We propose a scheme for sharing an arbitrary unknown two-qubit state among three parties by using afour-qubit cluster-class state and a Bell state as a quantum channel With a quantum controlled phase gate (QCPG)operation and a local unitary operation,any one of the two agents has the access to reconstruct the original state ifhe/she collaborates with the other one,whilst individual agent obtains no information.As all quantum resource canbe used to carry the useful information,the intrinsic efficiency of qubits approaches the maximal value.Moreover,thepresent scheme is more feasible with present-day technique.展开更多
Reaction of Cu with dibenzovi peroxide, 2-aminothiazol gave a binuclear complex [Cu_2 (C_6H_5COO)_4(C_3H_4N_2S)_2]. Crystal of the title compound is monoclinic system space group P2_1/n , M_r = 807. 84 with cell param...Reaction of Cu with dibenzovi peroxide, 2-aminothiazol gave a binuclear complex [Cu_2 (C_6H_5COO)_4(C_3H_4N_2S)_2]. Crystal of the title compound is monoclinic system space group P2_1/n , M_r = 807. 84 with cell parameters a= 10. 685 ( 1 ), b=19. 028(6), c=17. 046(9) , β=96. 49(33)￣°, Z=4, V=3443. 4, D_c=1. 565 g/cm￣-3, μ= 14. 078 cm￣-1, F(000)= 824. The final refinement with 3429 observed reflections is converged with R= 0. 046 and R_w=0. 053. X-ray crystal structure analysis revealed that each copper ion is coordinated by four bridging birfentate benzoate ligandsand one Zaminothiazol to form a binuclear molecule. In the crvstal, there are intramolecular hydrogen bonds N (1)- H ( 1 )-O(4) and N (3)- H (3)-O(1) with NO distance of 3. 005, N-H-O angle of 131. 9°.展开更多
目的通过对新疆伊犁哈萨克自治州(简称伊犁州)2011—2018年艾滋病防治工作各项指标进行综合评价与分析,从整体上把握艾滋病防治效果变化趋势,为持续改进艾滋病防治工作提供依据。方法采用TOPSIS(technique for order preference by simi...目的通过对新疆伊犁哈萨克自治州(简称伊犁州)2011—2018年艾滋病防治工作各项指标进行综合评价与分析,从整体上把握艾滋病防治效果变化趋势,为持续改进艾滋病防治工作提供依据。方法采用TOPSIS(technique for order preference by similarity to ideal solution)法和综合指数法对新疆伊犁州2011—2018年艾滋病防治工作效果进行综合评价和排序。结果TOPSIS法评价结果显示:2011年Ci值最低为0.0287,2018年Ci值最高为0.9795;综合指数法评价结果显示:2011年综合指数最低为0.84,2017及2018年综合指数最高为1.10。两种评价方法结果均显示新疆伊犁州2011—2018年艾滋病防治效果呈逐年优化趋势。结论新疆伊犁州2011—2018年艾滋病防治工作效果不断改善。TOPSIS法和综合指数法可进行多指标综合评价,能够应用于艾滋病防治工作效果评价,可以更加客观有效的反映艾滋病防治效果。展开更多
基金High-level Talent Project of the Hainan Province (No.820RC628)National Natural Science Foundation of China (No.82060378,81860367)+1 种基金Natural Science Foundation Youth Project of Hainan Province (No.820QN267)Cultivation Fund of Hainan Medical College (No.HYPY201919)。
文摘Scrub typhus is an acute febrile vector-borne zoonotic disease caused by the obligate intracellular growth bacterium Orientia tsutsugamushi(Ot).Mites are the primary vectors and rodents play a pivotal role in the transmission of scrub typhus.Due to the climate warming,increased human activity and other factors,cases of scrub typhus have been increased sharply during the past decade in China,especially in the northern China.To understand the incidence trend,epidemic pattern,clinical sign,diagnosis and therapy of this diseases as well as genotype evolution of Orientia tsutsugamushi,we summarized and analyzed the current knowledge of scrub typhus in China from 2010 to 2020.The data indicated that the dominate genotypes of scrub typhus in China were Karp,Kato and Gilliam.Although the disease was distributed national wide,Yunnan,Guangzhou and Fujian showed the highest incidence rate.The main vector of scrub typhus in southwest,middle east and southeast of China appeared a geographic preference respectively.Seasonal timing,age and occupation were the key factors that relate to the peak incidence of scrub typhus.Notably,farmer was the occupation with the highest risk of Ot infection.Further study on the epidemic characteristics,risk factors,diagnosis and treatments of scrub typhus will be of benefit to a comprehensive guideline for prevention and control of this ancient disease.
基金Key Science and Technology Project of Hainan Province(No.ZDKJ202003)Hainan Provincial Natural Science Foundation of China(No.821QN262)+1 种基金Hainan Provincial Natural Science Foundation of China(No.2019RC207)Hainan Provincial Natural Science Foundation of China(No.820RC628)。
文摘Objective:To study the in vitro virucidal activity of 9 extracts of traditional Chinese herbal medicine(the water extracts of Evodia lepta,Clausena lansium,Clerodendrum cyrtophyllum,Callicarpa nudiflora,Nauclea officinalis and Elaeagnus gonyanthes,the alcohol extracts of Nauclea officinalis,Elaeagnus gonyanthes and Zanthoxylumarmatum)on human respiratory syncytial virus(HRSV).Methods:The cytotoxic effect of the extracts on cells was evaluated by a cell viability assay using the CCK-8 method,a concentration of the extracts with cell viability greater than 50%was selected for the follow-up anti-HRSV effect assay,the 50%effective concentration(EC50)was assessed by an in vitro cell infection model.Results:The EC50s of the water extract from Clerodendrum cyrtophyllum,Callicarpa nudiflora and Elaeagnus gonyanthes were 0.05 mg/mL,0.03 mg/mL and 0.05 mg/mL,and the therapeutic index(TI)of them were 18.60,21.67 and 56.80 respectively.Conclusion:The water extracts of Clerodendrum cyrtophyllum,Callicarpa nudiflora and Elaeagnus gonyanthes possess the activity of anti-HRSV virus.
基金supported by the Postgraduate Innovation Research Plan from Anhui University under Grant No.20073039
文摘We present a novel protocol for deterministic secure quantum communication by using the four-qubit clusterstate as quantum channel.It is shown that two legitimate users can directly transmit the secret messages based on Bell-basis measurements and classical communication.The present protocol makes use of the ideas of block transmission anddecoy particle checking technique.It has a high capacity as each cluster state can carry two bits of information,and hasa high intrinsic efficiency because almost all the instances except the decoy checking particles (its number is negligible)are useful.Furthermore,this protocol is feasible with present-day technique.
文摘We propose two schemes for quantum secure direct communication (QSDC) and deterministic securequantum communication (DSQC) over collective dephasing noisy channel.In our schemes,four special two-qubit statesare used as the quantum channel.Since these states are unchanged through the collective dephasing noisy channel,the effect of the channel noise can be perfectly overcome.Simultaneously,the security against some usual attacks canbe ensured by utilizing the various checking procedures.Furthermore,these two schemes are feasible with present-daytechnique.
基金Supported by the Natural Science Research Programme of the Education Department of Anhui Province under Grant Nos.KJ2009B039Z and KJ2009B018Zthe Municipal Level Research Project from Lu'an City directive entrusted to West AnHui University under Grant No.2008LW004
文摘We propose a scheme for sharing an arbitrary unknown two-qubit state among three parties by using afour-qubit cluster-class state and a Bell state as a quantum channel With a quantum controlled phase gate (QCPG)operation and a local unitary operation,any one of the two agents has the access to reconstruct the original state ifhe/she collaborates with the other one,whilst individual agent obtains no information.As all quantum resource canbe used to carry the useful information,the intrinsic efficiency of qubits approaches the maximal value.Moreover,thepresent scheme is more feasible with present-day technique.
文摘Reaction of Cu with dibenzovi peroxide, 2-aminothiazol gave a binuclear complex [Cu_2 (C_6H_5COO)_4(C_3H_4N_2S)_2]. Crystal of the title compound is monoclinic system space group P2_1/n , M_r = 807. 84 with cell parameters a= 10. 685 ( 1 ), b=19. 028(6), c=17. 046(9) , β=96. 49(33)￣°, Z=4, V=3443. 4, D_c=1. 565 g/cm￣-3, μ= 14. 078 cm￣-1, F(000)= 824. The final refinement with 3429 observed reflections is converged with R= 0. 046 and R_w=0. 053. X-ray crystal structure analysis revealed that each copper ion is coordinated by four bridging birfentate benzoate ligandsand one Zaminothiazol to form a binuclear molecule. In the crvstal, there are intramolecular hydrogen bonds N (1)- H ( 1 )-O(4) and N (3)- H (3)-O(1) with NO distance of 3. 005, N-H-O angle of 131. 9°.
文摘目的通过对新疆伊犁哈萨克自治州(简称伊犁州)2011—2018年艾滋病防治工作各项指标进行综合评价与分析,从整体上把握艾滋病防治效果变化趋势,为持续改进艾滋病防治工作提供依据。方法采用TOPSIS(technique for order preference by similarity to ideal solution)法和综合指数法对新疆伊犁州2011—2018年艾滋病防治工作效果进行综合评价和排序。结果TOPSIS法评价结果显示:2011年Ci值最低为0.0287,2018年Ci值最高为0.9795;综合指数法评价结果显示:2011年综合指数最低为0.84,2017及2018年综合指数最高为1.10。两种评价方法结果均显示新疆伊犁州2011—2018年艾滋病防治效果呈逐年优化趋势。结论新疆伊犁州2011—2018年艾滋病防治工作效果不断改善。TOPSIS法和综合指数法可进行多指标综合评价,能够应用于艾滋病防治工作效果评价,可以更加客观有效的反映艾滋病防治效果。
