In this study, tribological and electrochemical performances of the new biomimetic synovial fluids were studied according to different composition concentrations, including hyaluronic acid, albumin and alendronic acid...In this study, tribological and electrochemical performances of the new biomimetic synovial fluids were studied according to different composition concentrations, including hyaluronic acid, albumin and alendronic acid sodium. By using Taguchi method, the composition contents of the biomimetic synovial fluids were designed. Items such as friction coefficient, mean scar diameter and viscosity were investigated via a four-ball tribo-tester, viscosity meter and optical microscope. Polarization studies were carried out to analyze the electrochemical behaviour of the fluids. Results showed that hyaluronic acid dominates the viscosity of the fluids. High albumin concentration will reduce friction, while increasing wear rate due to the electro-chemical effect. Alendronic acid sodium is found to reduce the biocorrosion of CoCrMo as well as provide better lubricating. In conclusion, biomimetic synovial fluids partially recover the functions of natural synovial fluids and provide good lubricating property.展开更多
文摘目的研究医用接骨螺钉的旋动扭矩计算模型。方法分析自攻型接骨螺钉在旋入过程中的3个主要阶段,对螺纹形成阶段的扭矩与扭转角进行力学建模与模拟计算;同时,根据ASTM F543-17(YY/T 1506-2016)标准的要求,对来自3个厂家的规格均为φ2.9×12接骨螺钉在不同等级聚氨酯实验块上开展螺钉体外旋入实验,将实验结果与计算结果进行比较分析。结果理论模型所得与实验测得最大旋入扭矩偏差值分别为5、12 m N·m,小于实验测得扭矩的10%,在可接受的误差范围内。结论所开发的接骨螺钉旋动力学计算模型能够模拟并预测研发与临床应用中的旋动扭矩,结合体外扭动实验,能够为接骨螺钉的研发与设计提供一种有效途径。
基金supported by the National Science Foundation of China (Grant No 50105014)the Ministry of Education (Grant No NCET-070535)+2 种基金the Science and Technology Committee of Shanghai Municipality (Grant Nos 08QH14007, 09PJ1407200)Shanghai Leading Academic Discipline Project (Grant No S30205)the Graduate Innovation Fund of Shanghai University (Grant No A16-0109-10-002)
文摘In this study, tribological and electrochemical performances of the new biomimetic synovial fluids were studied according to different composition concentrations, including hyaluronic acid, albumin and alendronic acid sodium. By using Taguchi method, the composition contents of the biomimetic synovial fluids were designed. Items such as friction coefficient, mean scar diameter and viscosity were investigated via a four-ball tribo-tester, viscosity meter and optical microscope. Polarization studies were carried out to analyze the electrochemical behaviour of the fluids. Results showed that hyaluronic acid dominates the viscosity of the fluids. High albumin concentration will reduce friction, while increasing wear rate due to the electro-chemical effect. Alendronic acid sodium is found to reduce the biocorrosion of CoCrMo as well as provide better lubricating. In conclusion, biomimetic synovial fluids partially recover the functions of natural synovial fluids and provide good lubricating property.
