基于CiteSpace的中医药防治心肌缺血再灌注损伤知识图谱分析

目的探讨国内外中医药防治心肌缺血再灌注损伤(Myocardial ischemia reperfusion injury,MIRI)的发展前沿及研究热点,为进一步相关研究提供参考。方法检索CNKI和WOS建库至2023年10月31日期间中医药防治MIRI的文献,用CiteSpace 6.2.R4进行作者合作网络图谱、机构合作网络图谱、关键词聚类图谱、关键词突现图谱展示并进行分析。结果共纳入2865篇中文文献,160篇英文文献,国内外主要受关注的研究作者分别是李冀和Jin Chen、主要研究机构分别是黑龙江中医药大学和Chinese Academy of Medical Sciences-Peking Union Medical College,关键词共现及突现分析表明国内外MIRI中医药干预措施包括中药、中药复方、中药单体、电针,研究热点为铁死亡、细胞焦亡和内质网应激。结论在中医药防治MIRI研究中,应加强国内研究团队之间的合作,促进国内研究机构的联系,结合研究热点,全面发展该领域。

温胆汤加减治疗冠心病合并焦虑抑郁疗效的系统评价和meta分析

目的:系统评价温胆汤加减联合常规西药治疗冠心病合并焦虑抑郁的临床疗效。方法:系统检索4个中文数据库:CNKI、WangFang、VIP、SinoMed,和5个英文数据库:PubMed、Cochrane Library、Web of Science、EMBASE、Springer Link,检索温胆汤治疗冠心病合并焦虑抑郁的临床随机对照试验,检索年限为各数据库建库至2022年1月。根据制定的纳排标准筛选文献,并对文献进行资料提取和质量评价,应用RevMan 5.3软件进行统计分析。结果:纳入13项RCT研究,共1 007名冠心病合并焦虑抑郁患者。Meta分析结果显示,温胆汤加减联合常规西药治疗在提高临床焦虑改善率[RR=1.21,95%CI=(1.12,1.31),P<0.000 01]、提高抑郁改善率[RR=1.30,95%CI=(1.10,1.53),P=0.002]、提高心绞痛改善率[RR=1.28,95%CI=(1.13,1.44),P<0.000 1]、提高ECG改善率[RR=1.29,95%CI=(1.07,1.55),P=0.008]、提高硝酸甘油减停率[RR=1.68,95%CI=(1.25,2.25),P=0.000 6]及提高中医症状改善率[RR=1.15,95%CI=(1.04,1.26),P=0.004]上均具有优势,在降低临床焦虑抑郁评分(SAS、SDS、HAMA、HAMD)、SAQ评分及中医症状评分上均具有较好的优势,差异具有统计学意义。结论:温胆汤加减联合常规西药在治疗冠心病合并焦虑抑郁患者的临床总有效率、降低心绞痛评分及焦虑抑郁评分、改善中医临床症状上具有一定的优势。

水稻新品种早籼14的选育与轻简化栽培技术

早籼14是由江西农业大学农学院选育的早稻早熟常规稻品种,2022年通过江西省品种审定,表现早熟、高产、稳产和抗倒等特性,适合直播、抛秧、机插等轻简化栽培。简述了早籼14的选育过程及轻简化栽培技术。

Efficacy of Wendan Decoction series for coronary heart disease with anxiety and depression:A systematic review and meta-analysis

Objective:To systematically evaluate the clinical efficacy of Wendan Decoction series combined with conventional western medicine in the treatment of coronary heart disease complicated with anxiety and depression.Methods:We searched four Chinese databases including CNKI,WanFang,VIP,SinoMed,and five English databases of PubMed,Cochrane Library,Web of Science,EMBASE,Springer Link for clinical randomized controlled trials of using Wendan Decoction series in the treatment of coronary heart disease complicated with anxiety and depression.Time range for searching was from the establishment of these databases to January 2022.Then we screened the retrieved literature according to the inclusion and exclusion criteria,and conducted data extraction and quality evaluation of the selected literature.Meta analysis was conducted using RevMan 5.3 software.Results:A total of 13 RCT studies and 1007 patients with coronary heart disease complicated with anxiety and depression were included.Meta-analysis showed that Wendan Decoction series combined with conventional western medicine treatment showed better effects in the improvement rate of clinical anxiety[RR=1.21,95%CI=(1.12,1.31),P<0.00001],the improvement rate of depression[RR=1.30,95%CI=(1.10,1.53),P=0.002],the improvement rate of angina pectoris[RR=1.28,95%CI=(1.13,1.44),P<0.0001],increasing the ECG improvement rate[RR=1.29,95%CI=(1.07,1.55),P=0.008],increasing the rate of reducing nitroglycerin usage[RR=1.68,95%CI=(1.25,2.25,P=0.0006],as well as increasing the improvement rate of TCM symptoms[RR=1.15,95%CI=(1.04,1.26),P=0.004].It also showed better effects in reducing clinical anxiety and depression scores(SAS,SDS,HAMA,HAMD),SAQ scores and TCM symptom scores.The differences were statistically significant.Conclusion:Wendan Decoction series combined with conventional western medicine shows advantages in treating coronary heart disease patients complicated with anxiety and depression in reducing the angina pectoris score,anxiety and depression score,as well as improving the clinical TCM symptoms.

农村污染源现状与治理对策

通过调查分析农村污染源的类型与现状,提出了农村污染源的治理办法和可持续利用措施。

聚乙烯亚胺的合成及应用

聚乙烯亚胺(PEI)是一种应用广泛的材料,具有特殊的性能。综述了聚乙烯亚胺的合成方法,概述了聚乙烯亚胺在采油领域、医用领域、水处理领域、湿部化学领域和CO2吸附领域的应用,指出了降低生产成本是聚乙烯亚胺拓宽应用的发展方向。