目的分析食管癌根治术后患者行早期营养护理干预的效果。方法便利选取2021年6月—2023年6月徐州市中心医院收治的98例食管癌根治术患者作为研究对象,采用随机数表法分为两组,各49例。对照组实施常规护理,观察组实施早期营养护理。对比...目的分析食管癌根治术后患者行早期营养护理干预的效果。方法便利选取2021年6月—2023年6月徐州市中心医院收治的98例食管癌根治术患者作为研究对象,采用随机数表法分为两组,各49例。对照组实施常规护理,观察组实施早期营养护理。对比两组营养风险筛查量表(Nutrition Risk Screening-2002,NRS-2002)评分、微型营养评定简表(Mini Nutritional Assessment Short Form Version,MNASF)评分、免疫功能、营养不耐受发生率。结果护理后,观察组NRS-2002评分较对照组更低,差异有统计学意义(P<0.05);观察组MNASF评分为(11.27±1.56)分,较对照组的(9.02±1.14)分更高,差异有统计学意义(t=8.152,P<0.05);观察组免疫功能指标均优于对照组,差异有统计学意义(P均<0.05);观察组营养不耐受发生率(6.12%)较对照组(20.41%)更低,差异有统计学意义(χ^(2)=4.346,P<0.05)。结论食管癌根治术后行早期营养护理可改善患者营养状态,提升其营养水平与免疫功能,且营养不耐受发生率较低。展开更多
The DNA of human factor Ⅸ (hFⅨ) gene vector pMCⅨm, which had been proven to be able to express in in vitro and living cells, was introduced into 586 zygotes of Kunming White Mice by positive pressure microinjection...The DNA of human factor Ⅸ (hFⅨ) gene vector pMCⅨm, which had been proven to be able to express in in vitro and living cells, was introduced into 586 zygotes of Kunming White Mice by positive pressure microinjection technique with manual operation. The 499 survival embryos after microinjection were then transferred into pseudopregnant recipient mice and 216 F 0 pups were born. The analysis of PCR and Southern blot hybridization showed that, of the 216, 6 (2 females and 4 males) were integrated with foreign DNA in their genomes, giving an integration frequency of 3% (6/216). Two F\-0 female transgenic mice could express hFⅨ protein in their milk and the content was over 100 ng/mL as measured with ELISA. The biological activities of hFⅨ in the milk of two F\-0 mice were 44 67% and 79 43%, respectively.展开更多
文摘目的分析食管癌根治术后患者行早期营养护理干预的效果。方法便利选取2021年6月—2023年6月徐州市中心医院收治的98例食管癌根治术患者作为研究对象,采用随机数表法分为两组,各49例。对照组实施常规护理,观察组实施早期营养护理。对比两组营养风险筛查量表(Nutrition Risk Screening-2002,NRS-2002)评分、微型营养评定简表(Mini Nutritional Assessment Short Form Version,MNASF)评分、免疫功能、营养不耐受发生率。结果护理后,观察组NRS-2002评分较对照组更低,差异有统计学意义(P<0.05);观察组MNASF评分为(11.27±1.56)分,较对照组的(9.02±1.14)分更高,差异有统计学意义(t=8.152,P<0.05);观察组免疫功能指标均优于对照组,差异有统计学意义(P均<0.05);观察组营养不耐受发生率(6.12%)较对照组(20.41%)更低,差异有统计学意义(χ^(2)=4.346,P<0.05)。结论食管癌根治术后行早期营养护理可改善患者营养状态,提升其营养水平与免疫功能,且营养不耐受发生率较低。
文摘The DNA of human factor Ⅸ (hFⅨ) gene vector pMCⅨm, which had been proven to be able to express in in vitro and living cells, was introduced into 586 zygotes of Kunming White Mice by positive pressure microinjection technique with manual operation. The 499 survival embryos after microinjection were then transferred into pseudopregnant recipient mice and 216 F 0 pups were born. The analysis of PCR and Southern blot hybridization showed that, of the 216, 6 (2 females and 4 males) were integrated with foreign DNA in their genomes, giving an integration frequency of 3% (6/216). Two F\-0 female transgenic mice could express hFⅨ protein in their milk and the content was over 100 ng/mL as measured with ELISA. The biological activities of hFⅨ in the milk of two F\-0 mice were 44 67% and 79 43%, respectively.
