AIM To compare the features ofgastroesophageal reflux disease between elderlyand younger patients.METHODS Twenty-four hour pH-monitoring andendoscopy were P6rformed for the 66 elderlypatients with typical gastroesopha...AIM To compare the features ofgastroesophageal reflux disease between elderlyand younger patients.METHODS Twenty-four hour pH-monitoring andendoscopy were P6rformed for the 66 elderlypatients with typical gastroesophageaI refluxsymptoms, and the results were compared with112 symptomatic younger patients.RESULTS The results of 24-h pH-monitoringand endoscopy showed that the elderly patientshad pathological reflux and reflux esophagitismore frequently than the younger patients.P6rcentage time with pH< 4 in elderly patientswith reflux esophagitis was 32.5% in 24 hours,as compared with 12.9% in the younger patientswith reflux esophagitis (P < 0 .05 ). The elderlypatients with reflux esophagitis have longerP6riOds of acid reflux in both upright and Supinepositions than the younger patients. Endoscopyshowed that 20 .8% of elderIy patients had grade Ⅲ / Ⅳ esophagitis, whereas only 3.4% ofyounger patients had grade Ⅲ/ Ⅳ esophagitis(P < 0.002 ). Percentages of grades Ⅰ /Ⅱesophagitis in the two groups were 12.5% and26. 5%, respectiveIy (P< 0. 002 ).CONCLUSION Elderly patients, as comparedwith younger patients, have more severegastroesophageal reflux and esophageal lesions.The incompetence of lower esophageal sphincter and the presence of hiataI hernia may beimportant factors leading to the difference in incidence and severity of reflux esophagitisbetween elderly and younger patients.展开更多
Granite is well known as an acid aggregate. An active mineral filler produced in the laboratory is first used as an anti-stripping filler in the granite asphalt concrete. Four aggregate gradations were chosen in this ...Granite is well known as an acid aggregate. An active mineral filler produced in the laboratory is first used as an anti-stripping filler in the granite asphalt concrete. Four aggregate gradations were chosen in this study,and the effects of the active mineral filler and aggregates on the rutting resistance performance and fatigue properties of granite asphalt concrete were investigated by means of rutting test and four-point bending fatigue test. The results indicate that the dynamic stability of granite asphalt concrete increase significantly with the addition of active mineral filler and the fatigue properties can also be improved especially at lower strain level. Meanwhile,the results demonstrate that granite asphalt concrete has better rutting resistance performance and fatigue properties than limestone asphalt concrete.展开更多
文摘AIM To compare the features ofgastroesophageal reflux disease between elderlyand younger patients.METHODS Twenty-four hour pH-monitoring andendoscopy were P6rformed for the 66 elderlypatients with typical gastroesophageaI refluxsymptoms, and the results were compared with112 symptomatic younger patients.RESULTS The results of 24-h pH-monitoringand endoscopy showed that the elderly patientshad pathological reflux and reflux esophagitismore frequently than the younger patients.P6rcentage time with pH< 4 in elderly patientswith reflux esophagitis was 32.5% in 24 hours,as compared with 12.9% in the younger patientswith reflux esophagitis (P < 0 .05 ). The elderlypatients with reflux esophagitis have longerP6riOds of acid reflux in both upright and Supinepositions than the younger patients. Endoscopyshowed that 20 .8% of elderIy patients had grade Ⅲ / Ⅳ esophagitis, whereas only 3.4% ofyounger patients had grade Ⅲ/ Ⅳ esophagitis(P < 0.002 ). Percentages of grades Ⅰ /Ⅱesophagitis in the two groups were 12.5% and26. 5%, respectiveIy (P< 0. 002 ).CONCLUSION Elderly patients, as comparedwith younger patients, have more severegastroesophageal reflux and esophageal lesions.The incompetence of lower esophageal sphincter and the presence of hiataI hernia may beimportant factors leading to the difference in incidence and severity of reflux esophagitisbetween elderly and younger patients.
基金Department of Transportation in Hubei Province,China and Headguarters of Ma-Wu Expressway in Hubei Province for its financial support of this work.
文摘Granite is well known as an acid aggregate. An active mineral filler produced in the laboratory is first used as an anti-stripping filler in the granite asphalt concrete. Four aggregate gradations were chosen in this study,and the effects of the active mineral filler and aggregates on the rutting resistance performance and fatigue properties of granite asphalt concrete were investigated by means of rutting test and four-point bending fatigue test. The results indicate that the dynamic stability of granite asphalt concrete increase significantly with the addition of active mineral filler and the fatigue properties can also be improved especially at lower strain level. Meanwhile,the results demonstrate that granite asphalt concrete has better rutting resistance performance and fatigue properties than limestone asphalt concrete.
