Neuroimaging studies of language networks in patients with brain lesions of t he left language dominant hemisphere have shown activation in the right inferi or frontal gyrus (IFG). We tested the functional relevance...Neuroimaging studies of language networks in patients with brain lesions of t he left language dominant hemisphere have shown activation in the right inferi or frontal gyrus (IFG). We tested the functional relevance of right IFG activati on using neuroimaging guided repetitive transcranial magnetic stimulation (rTM S) to disturb language function over bilateral IFG in right handed patients wi th brain tumors and controls. All subjects were susceptible to TMS over the left IFG. In patients, this susceptibility correlated with left sided the degree o f language lateralization to the left. Those patients with lowest dominance were also susceptible to right sided TMS proving relevant language function of the right IFG.展开更多
文摘Neuroimaging studies of language networks in patients with brain lesions of t he left language dominant hemisphere have shown activation in the right inferi or frontal gyrus (IFG). We tested the functional relevance of right IFG activati on using neuroimaging guided repetitive transcranial magnetic stimulation (rTM S) to disturb language function over bilateral IFG in right handed patients wi th brain tumors and controls. All subjects were susceptible to TMS over the left IFG. In patients, this susceptibility correlated with left sided the degree o f language lateralization to the left. Those patients with lowest dominance were also susceptible to right sided TMS proving relevant language function of the right IFG.
