BACKGROUND Few studies have simultaneously compared the predictive value of various frailty assessment tools for outcome measures in patients undergoing gastrointestinal cancer surgery.Therefore,it is difficult to det...BACKGROUND Few studies have simultaneously compared the predictive value of various frailty assessment tools for outcome measures in patients undergoing gastrointestinal cancer surgery.Therefore,it is difficult to determine which assessment tool is most relevant to the prognosis of this population.AIM To investigate the predictive value of three frailty assessment tools for patient prognosis in patients undergoing gastrointestinal cancer surgery.METHODS This single-centre,observational,prospective cohort study was conducted at the Affiliated Lianyungang Hospital of Xuzhou Medical University from August 2021 to July 2022.A total of 229 patients aged≥18 years who underwent surgery for gastrointestinal cancer were included in this study.We collected baseline data on the participants and administered three scales to assess frailty:The comprehen-sive geriatric assessment(CGA),Fried phenotype and FRAIL scale.The outcome measures were the postoperative severe complications and increased hospital RESULTS The prevalence of frailty when assessed with the CGA was 65.9%,47.6%when assessed with the Fried phenotype,and 34.9%when assessed with the FRAIL scale.Using the CGA as a reference,kappa coefficients were 0.398 for the Fried phenotype and 0.291 for the FRAIL scale(both P<0.001).Postoperative severe complications and increased hospital costs were observed in 29(12.7%)and 57(24.9%)patients,respectively.Multivariate logistic analysis confirmed that the CGA was independently associated with increased hospital costs(odds ratio=2.298,95%confidence interval:1.044-5.057;P=0.039).None of the frailty assessment tools were associated with postoperative severe complications.CONCLUSION The CGA was an independent predictor of increased hospital costs in patients undergoing surgery for gastro-intestinal cancer.展开更多
Background Respiratory syncytial virus(RSV)is the leading global cause of respiratory infections and is responsible for about 3 million hospitalizations and more than 100,000 deaths annually in children younger than 5...Background Respiratory syncytial virus(RSV)is the leading global cause of respiratory infections and is responsible for about 3 million hospitalizations and more than 100,000 deaths annually in children younger than 5 years,representing a major global healthcare burden.There is a great unmet need for new agents and universal strategies to prevent RSV infections in early life.A multidisciplinary consensus development group comprising experts in epidemiology,infectious diseases,respiratory medicine,and methodology aims to develop the current consensus to address clinical issues of RSV infections in children.Data sources The evidence searches and reviews were conducted using electronic databases,including PubMed,Embase,Web of Science,and the Cochrane Library,using variations in terms for"respiratory syncytial virus","RSV","lower respiratory tract infection","bronchiolitis","acute","viral pneumonia","neonatal","infant""children",and"pediatric".Results Evidence-based recommendations regarding diagnosis,treatment,and prevention were proposed with a high degree of consensus.Although supportive care remains the cornerstone for the management of RSV infections,new monoclonal antibodies,vaccines,drug therapies,and viral surveillance techniques are being rolled out.Conclusions This consensus,based on international and national scientific evidence,reinforces the current recommendations and integrates the recent advances for optimal care and prevention of RSV infections.Further improvements in the management of RSV infections will require generating the highest quality of evidence through rigorously designed studies that possess little bias and sufficient capacity to identify clinically meaningful end points.展开更多
A simplified minimum mean square error(MMSE) detector is proposed for joint detection and decoding of multi-ple-input multiple-output(MIMO) systems.The matrix inversion lemma and the singular value decomposition(SVD) ...A simplified minimum mean square error(MMSE) detector is proposed for joint detection and decoding of multi-ple-input multiple-output(MIMO) systems.The matrix inversion lemma and the singular value decomposition(SVD) of the channel matrix are used to simplify the computation of the coefficient of the MMSE filter.Compared to the original MMSE detector,the proposed detector has a much lower computational complexity with only a marginal performance loss.The proposed detector can also be applied to MIMO systems with high order modulations.展开更多
In this paper,we study the problem of optimal resource allocation for lifetime maximization in an orthogonal-frequencydivision multiplexing(OFDM)system with decode-and-forward relay.The goal is to minimize total energ...In this paper,we study the problem of optimal resource allocation for lifetime maximization in an orthogonal-frequencydivision multiplexing(OFDM)system with decode-and-forward relay.The goal is to minimize total energy cost of the system by jointly optimizing power allocation,subcarrier pairing and relay selection.We present a heuristic solution that is composed of two parts.The first part is an optimal power allocation approach to allocate power to a subcarrier pair of the source and the relay.The second part is a modified Hungarian algorithm to make subcarrier pairing and relay selection.Evaluations show that the presented scheme outperforms other schemes in the total transmitted data and the network lifetime.展开更多
基金the Postgraduate Research&Practice Innovation Program,No.SJCX22_1293Lianyungang City Aging Health Research Project,No.L202206.
文摘BACKGROUND Few studies have simultaneously compared the predictive value of various frailty assessment tools for outcome measures in patients undergoing gastrointestinal cancer surgery.Therefore,it is difficult to determine which assessment tool is most relevant to the prognosis of this population.AIM To investigate the predictive value of three frailty assessment tools for patient prognosis in patients undergoing gastrointestinal cancer surgery.METHODS This single-centre,observational,prospective cohort study was conducted at the Affiliated Lianyungang Hospital of Xuzhou Medical University from August 2021 to July 2022.A total of 229 patients aged≥18 years who underwent surgery for gastrointestinal cancer were included in this study.We collected baseline data on the participants and administered three scales to assess frailty:The comprehen-sive geriatric assessment(CGA),Fried phenotype and FRAIL scale.The outcome measures were the postoperative severe complications and increased hospital RESULTS The prevalence of frailty when assessed with the CGA was 65.9%,47.6%when assessed with the Fried phenotype,and 34.9%when assessed with the FRAIL scale.Using the CGA as a reference,kappa coefficients were 0.398 for the Fried phenotype and 0.291 for the FRAIL scale(both P<0.001).Postoperative severe complications and increased hospital costs were observed in 29(12.7%)and 57(24.9%)patients,respectively.Multivariate logistic analysis confirmed that the CGA was independently associated with increased hospital costs(odds ratio=2.298,95%confidence interval:1.044-5.057;P=0.039).None of the frailty assessment tools were associated with postoperative severe complications.CONCLUSION The CGA was an independent predictor of increased hospital costs in patients undergoing surgery for gastro-intestinal cancer.
基金sponsored by Key technology innovation projects of key industries in Chongqing (No.cstc2015zdcy-ztzx60011)Graduate Innovation Fund of Chongqing University of Technology (No.YCX2016109)
文摘Background Respiratory syncytial virus(RSV)is the leading global cause of respiratory infections and is responsible for about 3 million hospitalizations and more than 100,000 deaths annually in children younger than 5 years,representing a major global healthcare burden.There is a great unmet need for new agents and universal strategies to prevent RSV infections in early life.A multidisciplinary consensus development group comprising experts in epidemiology,infectious diseases,respiratory medicine,and methodology aims to develop the current consensus to address clinical issues of RSV infections in children.Data sources The evidence searches and reviews were conducted using electronic databases,including PubMed,Embase,Web of Science,and the Cochrane Library,using variations in terms for"respiratory syncytial virus","RSV","lower respiratory tract infection","bronchiolitis","acute","viral pneumonia","neonatal","infant""children",and"pediatric".Results Evidence-based recommendations regarding diagnosis,treatment,and prevention were proposed with a high degree of consensus.Although supportive care remains the cornerstone for the management of RSV infections,new monoclonal antibodies,vaccines,drug therapies,and viral surveillance techniques are being rolled out.Conclusions This consensus,based on international and national scientific evidence,reinforces the current recommendations and integrates the recent advances for optimal care and prevention of RSV infections.Further improvements in the management of RSV infections will require generating the highest quality of evidence through rigorously designed studies that possess little bias and sufficient capacity to identify clinically meaningful end points.
文摘A simplified minimum mean square error(MMSE) detector is proposed for joint detection and decoding of multi-ple-input multiple-output(MIMO) systems.The matrix inversion lemma and the singular value decomposition(SVD) of the channel matrix are used to simplify the computation of the coefficient of the MMSE filter.Compared to the original MMSE detector,the proposed detector has a much lower computational complexity with only a marginal performance loss.The proposed detector can also be applied to MIMO systems with high order modulations.
基金supported by Important National Science and Technology Specific Projects(No.2011ZX03003-001-04 and 2012ZX03003-012)National Natural Science Foundation of China(No.61072069)+2 种基金Fundamental Research Funds for the Central Universities(No.72101859)State Key Laboratory of Integrated Services Networks(No.ISN090105)111 Project(No.B08038)
文摘In this paper,we study the problem of optimal resource allocation for lifetime maximization in an orthogonal-frequencydivision multiplexing(OFDM)system with decode-and-forward relay.The goal is to minimize total energy cost of the system by jointly optimizing power allocation,subcarrier pairing and relay selection.We present a heuristic solution that is composed of two parts.The first part is an optimal power allocation approach to allocate power to a subcarrier pair of the source and the relay.The second part is a modified Hungarian algorithm to make subcarrier pairing and relay selection.Evaluations show that the presented scheme outperforms other schemes in the total transmitted data and the network lifetime.
