Dear Editor,Alzheimer’s disease(AD)is the most common cause of dementia among the older population,and is characterized by amyloid-beta(Aβ)accumulation,hyperphosphorylation of tau,and finally neurodegeneration in th...Dear Editor,Alzheimer’s disease(AD)is the most common cause of dementia among the older population,and is characterized by amyloid-beta(Aβ)accumulation,hyperphosphorylation of tau,and finally neurodegeneration in the brain[1].Aβ is the major pathological agent in AD,thus currently most efforts in developing therapies for AD target this peptide.The most promising therapy for this disease is immunotherapy.展开更多
基金This work was supported by the National Natural Science Foundation of China(81701046)Chongqing Science and Technology Commission(cstc2018jcyjAX0664).
文摘Dear Editor,Alzheimer’s disease(AD)is the most common cause of dementia among the older population,and is characterized by amyloid-beta(Aβ)accumulation,hyperphosphorylation of tau,and finally neurodegeneration in the brain[1].Aβ is the major pathological agent in AD,thus currently most efforts in developing therapies for AD target this peptide.The most promising therapy for this disease is immunotherapy.
