Hypertrophic cardiomyopathy(HCM)is genetic cardiomyopathy with the risk of sudden death characterized by abnormal sarcomere protein.^([1])Although some pathogenic genes related to HCM have been reported,^([2])the dise...Hypertrophic cardiomyopathy(HCM)is genetic cardiomyopathy with the risk of sudden death characterized by abnormal sarcomere protein.^([1])Although some pathogenic genes related to HCM have been reported,^([2])the disease phenotype and pathogenesis cannot be fully elucidated,which brings great difficulties to the diagnosis and treatment of HCM,especially the exploration of HCM treatment strategies.展开更多
基金supported by the National Natural Science Foundation of China(No.82070352)the Natural Science Foundation of Hunan Province(2022 JJ40765)the Natural Science Foundation of Changsha City,China(kq2202366).
文摘Hypertrophic cardiomyopathy(HCM)is genetic cardiomyopathy with the risk of sudden death characterized by abnormal sarcomere protein.^([1])Although some pathogenic genes related to HCM have been reported,^([2])the disease phenotype and pathogenesis cannot be fully elucidated,which brings great difficulties to the diagnosis and treatment of HCM,especially the exploration of HCM treatment strategies.
