Gait speed and hospitalization among ambulatory hemodialysis patients: USRDS special study data

AIM:To assess the association of measured gait speed with hemodialysis(HD)patients’hospitalization,in conjunction with,and apart from,recent fall history.METHODS:Gait speed was measured by a standard protocol and falls during the past 12 mo were ascertained for a prevalent multi-center HD cohort(n=668)aged 20-92.Hospitalization during the past 12 mo was identified in the patient’s clinic records,and the first hospitalization after gait speed assessment(or the competing event of death)was identified in the 2013 United States Renal Data System Standard Analysis Files.RESULTS:Slow gait speed,defined as<0.8 m/s,characterized 34.7%of the patients,and 27.1%had experienced a recent fall.Patients with slow gait speed but without a history of recent falls were 1.79 times more likely to have been hospitalized during the past12 mo(OR=1.79,95%CI:1.11-2.88,P=0.02),and patients with slow gait speed and a history of recent falls were over two times more likely to have been hospitalized(OR=2.10,95%CI:1.19-3.73,P=0.01),compared with patients having faster gait speed and no recent fall history.Prospective examination of gait speed/fall history status in relation to first hospitalization(or death)incurred by the end of follow-up December 31,2011 also showed that slow gait speed was associated with these events in conjunction with a history of falls(HR=1.54,95%CI:1.04-2.30,P=0.03).CONCLUSION:The International Task Force on Nutrition and Aging reported that gait speed is a powerful predictor for older adults of adverse outcomes such as hospitalization.In our data,gait speed--apart from,as well as in conjunction with,recent fall history--was associated with HD patients’hospitalization for multiple causes.Gait speed may be a sensitive health indicator among HD patients across the age spectrum.