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腔镜切割荷包吻合器在腹腔镜结直肠癌手术中的应用体会
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作者 张毅勋 关旭 +9 位作者 焦帅 张鑫 刘茂希 高晟 冯毅 王文渊 江波 白文启 刘海义 王锡山 《中华结直肠疾病电子杂志》 2024年第2期148-152,共5页
目的结直肠手术中进行腔镜下荷包缝合一直是手术操作的难点,尤其是经自然腔道取标本手术(NOSES)。同时结肠、直肠吻合口处形成的“危险三角区”又是增加吻合口漏的主要因素。腔镜切割荷包吻合器的临床应用可以有效解决上述技术难题。方... 目的结直肠手术中进行腔镜下荷包缝合一直是手术操作的难点,尤其是经自然腔道取标本手术(NOSES)。同时结肠、直肠吻合口处形成的“危险三角区”又是增加吻合口漏的主要因素。腔镜切割荷包吻合器的临床应用可以有效解决上述技术难题。方法本研究纳入5例行根治性手术的结直肠癌患者,包括4例直肠癌和1例乙状结肠癌。所有患者手术消化道重建过程中,乙状结肠荷包缝合及抵钉座固定步骤均使用腔镜切割荷包吻合器。结果患者平均年龄为(54.4±8.6)岁,患者平均BMI为(24.7±2.9)kg/m^(2)。4例患者行腹腔镜直肠癌根治+预防性末端回肠双腔造口术,1例患者行NOSES Ⅳ式。平均手术时间为(123.60±15.37)min,平均术中出血量为(98±36)mL,平均术后住院天数为(9.4±0.5)天。所有患者围术期均未出现并发症。结论腔镜直线荷包缝合器降低了全腔镜下乙状结肠与直肠消化道重建的操作难度。该设备的临床应用无论是对于常规腹腔镜手术,亦或是NOSES手术,都具有很好的临床价值与推广潜力。 展开更多
关键词 结直肠肿瘤 腹腔镜 腔镜切割荷包吻合器 经自然腔道取标本手术
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Femtosecond laser filamentation in simulated atmospheric turbulence[Invited] 被引量:1
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作者 郭杰伟 孙陆 +8 位作者 王悦政 薛嘉云 张智 刘海毅 陶诗诗 钱文启 齐鹏飞 林列 刘伟伟 《Chinese Optics Letters》 SCIE EI CAS CSCD 2023年第11期28-33,共6页
The effects of turbulence intensity and turbulence region on the distribution of femtosecond laser filaments are experimentally elaborated.Through the ultrasonic signals emitted by the filaments,it is observed that in... The effects of turbulence intensity and turbulence region on the distribution of femtosecond laser filaments are experimentally elaborated.Through the ultrasonic signals emitted by the filaments,it is observed that increasing turbulence intensity and an expanding turbulence active region cause an increase in the start position of the filament and a decrease in filament length,which can be well explained by theoretical calculation.It is also observed that the random perturbation of the air refractive index caused by atmospheric turbulence expands the spot size of the filament.Additionally,when the turbulence refractive index structure constant reaches 8.37×10^(-12)m^(-2/3),multiple filaments are formed.Furthermore,the standard deviation of the transverse displacement of filament is found to be proportional to the square root of the turbulent structure constant under the experimental turbulence parameters in this paper.These results contribute to the study of femtosecond laser propagation mechanisms in complex atmospheric turbulence conditions. 展开更多
关键词 femtosecond laser filamentation TURBULENCE
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Superconducting nanowire single-photon detectors:recent progress 被引量:3
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作者 Xiaolong Hu Yuhao Cheng +2 位作者 Chao Gu Xiaotian Zhu haiyi liu 《Science Bulletin》 SCIE EI CAS CSCD 2015年第23期1980-1983,共4页
Research of superconducting nanowire singlephoton detectors(SNSPDs) has been progressing rapidly in recent years. The combined properties of high efficiency,low noise, and fast speed of SNSPDs permit its applications ... Research of superconducting nanowire singlephoton detectors(SNSPDs) has been progressing rapidly in recent years. The combined properties of high efficiency,low noise, and fast speed of SNSPDs permit its applications ranging from long-distance quantum teleportation to moonto-earth optical communications. Here we briefly discussed recent progress of SNSPDs, in particular(1) tungstensilicide SNSPDs,(2) waveguide-integrated SNSPDs, and(3) a few applied demonstrations. 展开更多
关键词 Superconducting nanowire single-photon detectors · Quantum optics · Nanowire·Superconducting devices
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Differential immune responses in pregnant patients recovered from COYID-19
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作者 Ge Chen Yiming Zhang +16 位作者 Yaoyao Zhang Jihui Ai Bin Yang Mengge Cui Qiuyue Liao Hanxiao Chen Hualin Bai Dashing Shang Jing Chen ChaoYang Sun haiyi liu Fengyuan liu Bin Mao Guoqiang Sun Lu Chen Jing-wen Lin Kezhen Li 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2021年第8期2561-2575,共15页
Pregnant women are generally more susceptible to viral infection.Although the impact of SARS-CoV-2 in pregnancy remains to be determined,evidence indicates that the risk factors for severe COVID-19 are similar in preg... Pregnant women are generally more susceptible to viral infection.Although the impact of SARS-CoV-2 in pregnancy remains to be determined,evidence indicates that the risk factors for severe COVID-19 are similar in pregnancy to the general population.Here we systemically analyzed the clinical characteristics of pregnant and non-pregnant female COVID-19 patients who were hospitalized during the same period and found that pregnant patients developed marked lymphopenia and higher inflammation evident by higher C-reactive protein and IL-6.To elucidate the pathways that might contribute to immunopathology or protective immunity against COVID-19 during pregnancy,we applied single-cell mRNA sequencing to profile peripheral blood mononuclear cells from four pregnant and six non-pregnant female patients after recovery along with four pregnant and three non-pregnant healthy donors.We found normal clonal expansion of T cells in the pregnant patients,heightened activation and chemotaxis in NK,NKT,and MAIT cells,and differential interferon responses in the monocyte compartment.Our data present a unique feature in both innate and adaptive immune responses in pregnant patients recovered from COVID-19. 展开更多
关键词 PATIENTS protective IMMUNITY
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经辅助生殖技术妊娠患者早产的影响因素分析
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作者 粟睿 周璇 +20 位作者 杨殊琳 方晨韵 陈素华 邓东锐 曾万江 刘海意 龚洵 吴媛媛 刘燕燕 肖娟 余俊 何梦舟 李淑芳 王子琢 林星光 乌剑利 王少帅 岳静 靳镭 冯玲 丁文成 《中华产科急救电子杂志》 2024年第3期168-175,共8页
目的探讨经辅助生殖技术(assisted reproductive technology,ART)妊娠患者发生早产的影响因素。方法选取2022年1月至2023年12月期间在华中科技大学同济医学院附属同济医院产科分娩的ART患者369例,其中早产者189例(早产组),足月分娩者180... 目的探讨经辅助生殖技术(assisted reproductive technology,ART)妊娠患者发生早产的影响因素。方法选取2022年1月至2023年12月期间在华中科技大学同济医学院附属同济医院产科分娩的ART患者369例,其中早产者189例(早产组),足月分娩者180例(足月分娩组)。分析两组患者的一般资料、ART相关资料、妊娠期并发症、合并症以及新生儿情况,通过t检验和卡方检验分析两组间差异,通过Logistic回归分析影响早产的独立危险因素。结果早产组与足月分娩组比较,双胎妊娠率(40.7%vs 3.9%,χ^(2)=71.212)、孕前体质指数[(22.78±3.71)kg/m^(2) vs(21.62±3.12)kg/m^(2),t=-2.952]、原发不孕(63.8%vs 35.9%,χ^(2)=21.069)、体外受精(62.1%vs 42.2%,χ^(2)=10.491)、获卵数[(13.94±8.72)个vs(13.54±7.28)个,t=-0.402]、人绒毛膜促性腺激素注射日雌二醇水平[(2906.5±1892.0)pg/ml vs(2598.18±1456.5)pg/ml,t=-1.493]、胎膜早破(9.5%vs 0,χ^(2)=18.022)、妊娠期高血压疾病(16.9%vs 6.1%,χ^(2)=10.484)、宫颈机能不全(6.3%vs 0.6%,χ^(2)=9.105)以及卵巢相关疾病(6.3%vs 1.7%,χ^(2)=5.184)方面的差异均有统计学意义(P<0.05)。多因素Logistic回归分析提示双胎妊娠(OR=25.637,95%CI:8.782~74.844,P<0.001)、妊娠期高血压疾病(OR=2.809,95%CI:1.149~6.865,P<0.05)孕妇发生早产的风险显著增加。结论双胎妊娠、孕前超重和肥胖、原发不孕史、应用体外受精技术、获卵数多、人绒毛膜促性腺激素注射日雌二醇高水平、妊娠期高血压疾病、胎膜早破、宫颈机能不全、卵巢相关疾病均为ART妊娠患者早产的影响因素,其中妊娠期高血压疾病、双胎妊娠为ART患者早产的独立影响因素。 展开更多
关键词 生殖技术 辅助 早产 危险因素
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