政策文件替代计量作为时下热门研究领域altmetrics的重要组织部分,主要通过统计学术成果在政策文件中的提及频次测度其政策影响力。以Altmetric.com平台2012-2017年的政策文件替代计量数据为主要研究对象,从成果载体、内容客体、创作主...政策文件替代计量作为时下热门研究领域altmetrics的重要组织部分,主要通过统计学术成果在政策文件中的提及频次测度其政策影响力。以Altmetric.com平台2012-2017年的政策文件替代计量数据为主要研究对象,从成果载体、内容客体、创作主体、资助来源等方面关注被利用学术成果元数据的多层次分布态势,以及学术成果使用对象分布情况,揭示政府关注学术成果的程度及使用效率差异,并测度学术成果利用效率指标在不同层次上的相关性与差异性。研究发现:医学保健学科、期刊The Lancet、机构Harvard Univ、资助机构National Institutes of Health的学术成果被政策文件利用次数较多;美国及机构World Health Organization是政策文件主要的利用对象,且多被本土所使用;资助机构National Institutes of Health主要被美国及机构National Academies Press所提及。中国的学术成果主要为瑞士所使用,中国国家自然科学基金会的学术成果主要被美国政策文件提及,而被机构利用效率相对较低。整体上,不同层次学术成果的传统指标与替代计量指标间的相关性较强,学术界与政治界主要关注的热点方向趋同。展开更多
Objective: To investigate the correlation between 17-beta-hydroxysteroid dehydrogenase type1(17β-HSD-1) gene polymorphisms and risk of endometrial adenocarcino-ma.Methods: Forty-one patients with endometrial adenocar...Objective: To investigate the correlation between 17-beta-hydroxysteroid dehydrogenase type1(17β-HSD-1) gene polymorphisms and risk of endometrial adenocarcino-ma.Methods: Forty-one patients with endometrial adenocarcinoma were selected as experimen-tal group and twenty-seven healthy women were selected as control group.The three common single nucleotide polymorphism of 17β-HSD-1 gene at sites + 1004,+ 1322 and + 1954 were detected by allele-specific PCR(ASA-PCR).The allele frequencies were analyzed by SPSS13.0 software between endometrial cancer cases and controls.Results: We observed no significant difference in various frequency distribution between experimental group and control group.P1004= 0.994,P1322 = 0.974,and P1954 = 0.981.Conclusion: We found that three common SNPs with the 17β-HSD-1 gene were not associated with endometrial adenocarcinoma.We suggest that more research for 17β-HSD needs to explore.展开更多
文摘政策文件替代计量作为时下热门研究领域altmetrics的重要组织部分,主要通过统计学术成果在政策文件中的提及频次测度其政策影响力。以Altmetric.com平台2012-2017年的政策文件替代计量数据为主要研究对象,从成果载体、内容客体、创作主体、资助来源等方面关注被利用学术成果元数据的多层次分布态势,以及学术成果使用对象分布情况,揭示政府关注学术成果的程度及使用效率差异,并测度学术成果利用效率指标在不同层次上的相关性与差异性。研究发现:医学保健学科、期刊The Lancet、机构Harvard Univ、资助机构National Institutes of Health的学术成果被政策文件利用次数较多;美国及机构World Health Organization是政策文件主要的利用对象,且多被本土所使用;资助机构National Institutes of Health主要被美国及机构National Academies Press所提及。中国的学术成果主要为瑞士所使用,中国国家自然科学基金会的学术成果主要被美国政策文件提及,而被机构利用效率相对较低。整体上,不同层次学术成果的传统指标与替代计量指标间的相关性较强,学术界与政治界主要关注的热点方向趋同。
文摘Objective: To investigate the correlation between 17-beta-hydroxysteroid dehydrogenase type1(17β-HSD-1) gene polymorphisms and risk of endometrial adenocarcino-ma.Methods: Forty-one patients with endometrial adenocarcinoma were selected as experimen-tal group and twenty-seven healthy women were selected as control group.The three common single nucleotide polymorphism of 17β-HSD-1 gene at sites + 1004,+ 1322 and + 1954 were detected by allele-specific PCR(ASA-PCR).The allele frequencies were analyzed by SPSS13.0 software between endometrial cancer cases and controls.Results: We observed no significant difference in various frequency distribution between experimental group and control group.P1004= 0.994,P1322 = 0.974,and P1954 = 0.981.Conclusion: We found that three common SNPs with the 17β-HSD-1 gene were not associated with endometrial adenocarcinoma.We suggest that more research for 17β-HSD needs to explore.
