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2022年青海门源M_(S)6.9地震地表破裂带宽度调查与启示
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作者 牛鹏飞 韩竹军 +2 位作者 郭鹏 李科长 吕丽星 《地球物理学报》 SCIE EI CAS CSCD 北大核心 2024年第2期548-570,共23页
地震地表破裂带是地震破裂在地表的直接表现,其宽度是活断层"避让带"和工程抗震设防重要的指示参数.无人机等测量手段的发展为获取地表破裂带的高分辨率影像数据、精细测量破裂带宽度、分析破裂带宽度空间分布特征以及限定合... 地震地表破裂带是地震破裂在地表的直接表现,其宽度是活断层"避让带"和工程抗震设防重要的指示参数.无人机等测量手段的发展为获取地表破裂带的高分辨率影像数据、精细测量破裂带宽度、分析破裂带宽度空间分布特征以及限定合理的活断层"避让带"提供了有利条件.2022年门源M_(S)6.9地震在青藏高原东北缘冷龙岭与托莱山断裂阶区部位产生了显著的左旋走滑型地表破裂带.基于震后获取的高精度无人机正射影像和数字高程模型,文中在门源地震地表破裂带全段精细解译的基础上,沿走向间隔100 m测量了251个宽度数据,R1破裂带最大宽度为209.78±14 m,平均宽度为42 m,R2破裂带最大宽度为115.31±15.72 m,平均宽度为26.14 m.宽度沿走向具有差异性,这主要受控于同震变形强度、破裂带几何结构以及地表第四系松散层发育状况;具体表现为同震位移量大、阶区等复杂几何结构以及穿过第四系松散层区段的破裂带比同震位移量小、平直段以及基岩区段的破裂带要宽.通过对去除离散值后的破裂带宽度数据统计分析,计算出95.4%和68.2%置信区间的有效宽度分别是70或50 m.在工程抗震设防中,若走滑型活断层评估的最大潜在震级与此次门源地震震级相近(~M 7.0),根据建(构)筑物类别,建议确定"避让带"宽度时参考本文获得的破裂带有效宽度(70或50 m).对于单一走滑型错动面发育地段,按建(构)筑物类别向两侧各扩展35或25 m即可;而对于活断层斜列阶区、平行断层围限区、走向弯曲区和双陡倾角错动面发育地段,在这些复杂几何结构分布范围的基础上需要各向两侧扩展35或25 m.本文研究结果可为建(构)筑物选址避让走滑型断层提供参考依据. 展开更多
关键词 走滑型地震 地震地表破裂带 活断层"避让带"宽度 门源M_(S)6.9地震 工程抗震设防
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Seismotectonics of the 26 November 2005 Jiujiang-Ruichang,Jiangxi,Ms 5.7 Earthquake 被引量:6
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作者 han zhujun LUFushui +2 位作者 JI Fengju ZENG Xinfu An Yanfen 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2012年第2期497-509,共13页
The 26 November 2005 Jiujiang-Ruichang, Jiangxi, Ms 5.7 earthquake occurred in a seismotectonic setting of moderate earthquake. The northwest-trending Xiangfan-Guangji fault (XFG) does not enter into the epicenter v... The 26 November 2005 Jiujiang-Ruichang, Jiangxi, Ms 5.7 earthquake occurred in a seismotectonic setting of moderate earthquake. The northwest-trending Xiangfan-Guangji fault (XFG) does not enter into the epicenter vicinity, but the northeast-trending Ruichang-Wuning fault (RWF) as a regional fault extends to the epicenter nearby, appearing as the Ruichang basin and its marginal faults. Tilting of the Ruichang Basin (RCB) in the Quaternary was controlled by the RCB southeast- marginal, buried fault (RSMBF). Shallow geophysical survey reveals that the RSMBF caused an offset of the reflection layers. Drill hole columnar section demonstrates that there are about 10-12 m displacement in the lower section of the middle-Pleistocene Series along the RSMBF, but no disruption is found in the upper section of the middle-Pleistocene Series. The RSMBF not only has activity in the Quaternary, but also coincides with the nodal plane I from the focal mechanism of the Jiujiang- Ruichang Ms 5.7 earthquake. This evidence, including aftershock distribution and isoseismic lines, strongly suggests that the RSMBF might be the seismogenic tectonics. The RWF is discontinuous at the surface, and consists of three en echelon Quaternary basins, which are the Ruichang, Fanzhen and Wuning basins. Three moderate earthquakes, the Fanzhen ML 4.9 earthquake, the Yejiapu ML 4.1 earthquake and the Jiujiang-Ruichang Ms 5.7 earthquake, have happened in the basins since 1995. The seismogenic tectonics of the Jiujiang-Ruichang Ms 5.7 earthquake is not isolated, but may be controlled by the RWF at depth, the slip of which causes the accumulation of energy for earthquake occurrence. 展开更多
关键词 Jiujiang-Ruichang Ms 5.7 earthquake buried fault Ruichang basin seismo-tectonics
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异甘草酸镁的药理作用及临床应用研究进展
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作者 韩竹俊 许美娟 +2 位作者 刘玲 吉丽 崔俊丽 《药学与临床研究》 2023年第3期238-242,共5页
异甘草酸镁(MgIG)是18α-甘草酸立体异构体的镁盐,属于第四代甘草酸类制剂。MgIG通过促进肝细胞增殖、降酶或抗自由基、提高抗氧化酶活性等方式,呈现明显的抗炎、抗氧化、保肝护肝等效应。近年来相关研究显示MgIG对除肝脏外的其他器官... 异甘草酸镁(MgIG)是18α-甘草酸立体异构体的镁盐,属于第四代甘草酸类制剂。MgIG通过促进肝细胞增殖、降酶或抗自由基、提高抗氧化酶活性等方式,呈现明显的抗炎、抗氧化、保肝护肝等效应。近年来相关研究显示MgIG对除肝脏外的其他器官如肾、心、肺等也具有较好的保护作用。现本文对MgIG药理作用及临床应用作一综述。 展开更多
关键词 异甘草酸镁 抗炎 组织保护
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新西兰2016年凯库拉M_W 7.8地震灾害考察与启示 被引量:1
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作者 韩竹军 袁仁茂 +1 位作者 冉洪流 郭鹏 《震灾防御技术》 CSCD 北大核心 2018年第2期255-266,共12页
在2016年新西兰凯库拉M_W 7.8地震中,北东—北东东向科科仁古断裂水平右旋位移量最大,为10—12m;北北西—近南北向帕帕提断裂垂直位移量最大,达到5—6m。对直接坐落在这2条地震地表破裂带或变形带之上的建筑物的破坏现场调查表明,尽管... 在2016年新西兰凯库拉M_W 7.8地震中,北东—北东东向科科仁古断裂水平右旋位移量最大,为10—12m;北北西—近南北向帕帕提断裂垂直位移量最大,达到5—6m。对直接坐落在这2条地震地表破裂带或变形带之上的建筑物的破坏现场调查表明,尽管房屋出现歪斜,但上部主体部分基本完整,没有出现倒塌或部分倒塌现象,避免了人员伤亡。在无法回避活动断裂及其大震危险性的情况下,隔震系统的广泛采用可以有效地提高建筑物抵御地震灾害的能力。此次地震触发了数万个滑坡体,最大滑坡体可达数百万立方米。对沃罗村北边2处边坡失稳地带的考察结果表明,针对该地至少从2个方面进行了考虑和处置:一是在选址上,避开了突出山嘴等高陡坡地带;二是在房屋正对的山坡地带,种植或保护了茂密的树木,这既增加了山体的稳定性,又可以在地震中有效地减缓崩塌的石块对房屋的冲击。对比中国中东部一些大震,如1976年唐山7.8级地震和2008年汶川8.0级地震中触目惊心的巨大人员伤亡和财产损失,即使在人口密度与滑坡规模上存在明显不同,对新西兰凯库拉地震灾害现场的考察结果,还是在如何有效抵御地震灾害方面给我们提供了很好的启示。 展开更多
关键词 凯库拉地震 地震灾害防御 地表破裂带 地震滑坡
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原发性肝细胞癌的CT影像组学分析 被引量:2
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作者 韩柱君 巩贯忠 +3 位作者 路玉昆 仇清涛 尹勇 全红 《中国医学物理学杂志》 CSCD 2018年第12期1426-1429,共4页
目的:应用影像组学方法量化原发性肝细胞癌在CT增强扫描时"快进快出"的影像学表现。方法:在平扫期、动脉期、门脉期上勾画肿瘤靶区(GTV)和部分正常肝脏组织,提取所勾画靶区的特征值,量化GTV以及正常肝脏组织在不同时相上影像... 目的:应用影像组学方法量化原发性肝细胞癌在CT增强扫描时"快进快出"的影像学表现。方法:在平扫期、动脉期、门脉期上勾画肿瘤靶区(GTV)和部分正常肝脏组织,提取所勾画靶区的特征值,量化GTV以及正常肝脏组织在不同时相上影像组学特征值的差异。结果:共提取55个特征,正常肝脏组织和GTV在平扫期与动脉期、平扫期与门脉期、动脉期与门脉期所提取的特征差异具有统计学意义的分别有7、8、22个和35、41、33个;GTV与正常肝脏组织在平扫期差异具有统计学意义的特征有49个,动脉期46个,门脉期38个;有6个特征与"快进快出"现象有关。结论:基于影像组学技术量化不同强化时机肝细胞癌和正常肝脏组织的特征,为追踪肝细胞癌肿瘤异质性及动态变化提供有效的手段。 展开更多
关键词 影像组学 肝细胞癌 正常肝脏组织 CT增强图像
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小江断裂带南段新寨盆地新构造运动特征 被引量:4
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作者 陈君贤 韩竹军 程捷 《华南地震》 2021年第3期82-91,共10页
小江断裂带是新构造时期以来十分活跃的活动断裂带,沿线地震活动频繁,新寨盆地是其控制下发育的串珠状盆地之一。通过野外第四纪地质与构造地质填图,LiDAR扫描,无人机移动摄影测量等手段,对新寨盆地内部第四系地层分布和控盆断裂以及其... 小江断裂带是新构造时期以来十分活跃的活动断裂带,沿线地震活动频繁,新寨盆地是其控制下发育的串珠状盆地之一。通过野外第四纪地质与构造地质填图,LiDAR扫描,无人机移动摄影测量等手段,对新寨盆地内部第四系地层分布和控盆断裂以及其反映的构造活动期次进行研究,认为新近纪以挤压为主的应力过后,早更新世晚期小江断裂南段受元谋运动影响开始强烈左旋走滑运动,新寨盆地受其控制开始发育,全新世以来,断层偏离原先构造位置再次活动,具有一定的新生性和发震能力,晚更新世存在一个活动间歇期。 展开更多
关键词 小江断裂南段 新寨盆地 地质填图 地貌测量 新构造运动
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不同湿球温度对中部烟叶烘烤质量的影响 被引量:10
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作者 李昱霖 胡蓉花 +5 位作者 韩助君 李小勇 沈雪婷 潘瑞朋 肖子康 段史江 《天津农业科学》 CAS 2019年第11期34-38,共5页
为了进一步降低江西吉安烟区烤后烟叶的光滑僵硬烟比例,促进烟叶内部物质转化协调,提高烘烤质量。以‘云烟87’为试验材料,设置3组不同湿球温度对其进行处理(T1为变黄期中湿,定色期低湿烘烤工艺;T2为同步预热低湿变黄烘烤工艺;CK为传统... 为了进一步降低江西吉安烟区烤后烟叶的光滑僵硬烟比例,促进烟叶内部物质转化协调,提高烘烤质量。以‘云烟87’为试验材料,设置3组不同湿球温度对其进行处理(T1为变黄期中湿,定色期低湿烘烤工艺;T2为同步预热低湿变黄烘烤工艺;CK为传统三段式烘烤工艺),分析烘烤工艺对烤后中部烟叶的各项指标的影响。结果表明:T2处理(干球温度38℃/湿球温度前期37℃,后期35℃;干球温度42℃/湿球温度37℃;干球温度48℃,湿球温度38℃)烤后烟叶外观质量最好;主要经济性状,上等烟比例,中上等烟比例最高;化学成分,烟碱、总氮、钾含量较协调;香气物质,烟叶中的苯丙氨酸类香气物质总量较另外两个烘烤工艺有显著提高,香气物质总量无显著提高;感官评吸质量,香气质、燃烧性、灰分、使用价值均较CK有显著改善。T1次之;CK较差。总之,利用同步预热低湿变黄烘烤工艺对江西吉安烟叶进行烘烤,对烟叶的各个评价指标均有不同程度的改善,应优选同步预热低湿变黄烘烤工艺。 展开更多
关键词 烤烟 光滑僵硬烟 烘烤质量 湿球温度 中部烟叶
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Active Fault Exploration and Seismic Hazard Assessment in Fuzhou City 被引量:7
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作者 Zhu Jinfang Huang Zonglin +7 位作者 Xu Xiwei Zheng Rongzhang Fang Shengmin Bai Denghai Wang Guangcai Min Wei Wen Xueze han zhujun 《Earthquake Research in China》 2005年第3期224-239,共16页
It has been proven by a number of earthquake case studies that an active fault-induced earthquake beneath a city can be devastating. It is an urgent issue for seismic hazard reduction to explore the distribution of ac... It has been proven by a number of earthquake case studies that an active fault-induced earthquake beneath a city can be devastating. It is an urgent issue for seismic hazard reduction to explore the distribution of active faults beneath the urban area and identify the seismic source and the risks underneath. As a pilot project of active fault exploration in China, the project, entitled “Active fault exploration and seismic hazard assessment in Fuzhou City", started in early 2001 and passed the check before acceptance of China Earthquake Administration in August 2004. The project was aimed to solve a series of scientific issues such as fault location, dating, movement nature, deep settings, seismic risk and hazard, preparedness of earthquake prevention and disaster reduction, and etc. by means of exploration and assessment of active faults by stages, i.e., the preliminary survey and identification of active faults in target area, the exploration of deep seismotectonic settings, the risk evaluation of active seismogenic faults, the construction of geographic information system of active faults, and so on. A lot of exploration methods were employed in the project such as the detection of absorbed mercury, free mercury and radon in soil, the geological radar, multi-channel DC electrical method, tsansient electromagnetic method, shallow seismic refraction and reflection, effect contrast of explored sources, and various sounding experiments, to establish the buried Quaternary standard section of the Fuzhou basin. By summing up, the above explorations and experiments have achieved the following results and conclusions: (1)The results of the synthetic pilot project of active fault exploration in Fuzhou City demonstrate that, on the basis of sufficient collection, sorting out and analysis of geological, geophysical and borehole data, the best method for active fault exploration (location) and seismic risk assessment (dating and characterizing) in urban area is the combination of various approaches, that is, the possible location of active fault determined by using geochemical exploration as a guide “scout", the shallow seismic sounding as the main tool, the electromagnetic method as a supplement, establishing the standard Quaternary profile or stratigraphic sequence from drilling and various geophysical parameters from borehole logs as methods to correct and verify the data above. And in addition, the method also includes the field surveys on fault exposures, trenching, paleoearthquake investigation, dating and comparison of lithology, strata sequence, absolute or relative ages of the cores on the two sides of buried faults. (2)The Fuzhou basin locates under the regional seismotectonic settings which have the potential of moderate earthquake. Comparatively, the region is less affected by the “Taiwan dynamic Antenna"; (3)The activity of the major faults in Fuzhou basin is weak in general. All the six identified target faults are not Holocene faults, among which the Bayi Reservoir-Shanggan fault and the Minhou-Nanyu fault are dormant at least since the mid Epipleistocene time, and the rest are dormant since the Epipleistocene time; (4)In terms of deep-seated structures beneath the basin, there is no evidence indicating the possible occurrence of the underneath strong destructive earthquakes. The adjacent Changle-Zhao’an fault zone is the potential seismic source which may possibly affect Fuzhou City; (5)There exists potential of moderate-strong earthquake on the major faults of the region, but the probability is low; (6)The seismic hazards are weak in the region and the surface earthquake fractures are not likely to occur; (7)The first geographic information system of active faults is developed with functions of information query and display, data management, analysis and processing, etc. 展开更多
关键词 福州市 地震 活动性 安全性 地球构造
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上部不同成熟度鲜烟叶对烟叶烘烤质量的影响 被引量:4
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作者 曾宇 韩助君 +2 位作者 谭志能 焦绍赫 刘玉婷 《农业技术与装备》 2019年第11期8-9,12,共3页
用暗箱试验、烤房实际观测研究了上部不同成熟度鲜烟叶的烘烤特性,并分析了相对应的烤后烟叶质量,结果表明:上部鲜烟成熟度表现为落黄程度稍高、叶面呈现黄多青少、整体较为清秀的其烘烤特性最好,明显好于成熟度较高、有枯尖焦边成熟特... 用暗箱试验、烤房实际观测研究了上部不同成熟度鲜烟叶的烘烤特性,并分析了相对应的烤后烟叶质量,结果表明:上部鲜烟成熟度表现为落黄程度稍高、叶面呈现黄多青少、整体较为清秀的其烘烤特性最好,明显好于成熟度较高、有枯尖焦边成熟特征的,其烤后烟叶外观质量也最高。因此,适宜江西永丰的上部烟叶采收成熟度是叶面呈现黄多青少,整体较为清秀的状态。 展开更多
关键词 鲜烟叶 暗箱试验 烘烤特性
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低浓度茉莉酸甲酯对烟草长柄腺毛发生发育的影响
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作者 段史江 陈小龙 +7 位作者 吴飞跃 王占伟 程小强 张子颖 李亚纯 谢天琪 韩助君 杨永锋 《中国烟草科学》 CSCD 北大核心 2022年第6期17-24,共8页
茉莉酸甲酯(MeJA)对烟草长柄腺毛的发生具有强烈的诱导作用,但浓度过高时会抑制烟苗发育。本文以云烟87幼苗为材料,研究低浓度MeJA对腺毛发育和腺毛分泌物的影响,并利用qRT-PCR技术研究腺毛发生发育调控基因对MeJA的应答模式。结果表明... 茉莉酸甲酯(MeJA)对烟草长柄腺毛的发生具有强烈的诱导作用,但浓度过高时会抑制烟苗发育。本文以云烟87幼苗为材料,研究低浓度MeJA对腺毛发育和腺毛分泌物的影响,并利用qRT-PCR技术研究腺毛发生发育调控基因对MeJA的应答模式。结果表明,随着MeJA喷施浓度的升高,长柄腺毛的密度和腺头直径逐渐增加;喷施300μmol/L MeJA对长柄腺毛发生和发育有显著的诱导作用,且对叶片发育无明显影响;当MeJA喷施浓度达到600μmol/L时,叶片发育受到抑制。叶面化学成分分析发现,与未喷施MeJA的对照相比,喷施300μmol/L MeJA后西柏烷二萜、烷烃和蔗糖酯含量增加约一倍。基因应答模式研究发现,西柏烷二萜合成基因CBTS和CYP71D16,以及酯转运蛋白基因Nt LTP1受MeJA诱导表达;烟草腺毛发生调控基因ARF3、GIS、CD2、Wo和Cyc B2对MeJA处理均具有应答反应,其中ARF3和GIS的表达受到MeJA诱导,而CD2、Wo和Cyc B2的表达受到MeJA抑制。综上,300μmol/L MeJA可以调控腺毛发育相关基因的表达,安全、有效地促进长柄腺毛发生发育以及腺毛分泌物的合成。 展开更多
关键词 烟草 腺毛 茉莉酸甲酯 西柏烷二萜 蔗糖酯 基因表达
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Large-Scale Dextral Strike-Slip Movement and Associated Tectonic Deformation Along the Red-River Fault Zone
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作者 Xiang Hongfa han zhujun +2 位作者 Guo Shunmin Zhang Wanxia Chen Lichun 《Earthquake Research in China》 2005年第2期125-138,共14页
Field investigation has revealed that the large-scale dextral strike-slip movement and the associated tectonic deformation along the Red River fault zone have the following features: geometrically, the Red River fault... Field investigation has revealed that the large-scale dextral strike-slip movement and the associated tectonic deformation along the Red River fault zone have the following features: geometrically, the Red River fault zone can be divided into three deformation regions, namely, the north, central and south regions. The north region lies on the eastern side of the Northwest Yunnan extensional taphrogenic belt, which is characterized by the 3 sets of rift-depression basins striking NNW, NNE and near N-S since the Pliocene time, and on its western side is the Lanping-Yunlong compressive deformation belt of the Paleogene to Neogene; the deformation in the central region is characterized by dextral strike-slip or shearing. The east Yunnan Miocene compressive deformation belt lies on the eastern side of the fault in the south, and the Tengtiaohe tensile fault depression belt is located on its west. In terms of tectonic geomorphology, the aforementioned deformation is represented by basin-range tectonics in the north, linear faulted valley-basins in the central part and compressive (or tensional) basins in the south. Among them, the great variance in elevation of the planation surfaces on both sides of the Cangshan-Erhai fault suggests prominent normal faulting along the Red River fault since the Pliocene. From the viewpoint of spatial-temporal evolution, the main active portion of the fault was the southern segment in the Paleogene-Miocene-Pliocene, which is represented by “tearing” from south to north. The main active portion of the fault has migrated to the northern segment since the Pliocene, especially in the late Quaternary, which is characterized by extensional slip from north to southeast. The size of the deformation region and the magnitude of deformation show that the eastern plate of the Red River fault has been an active plate of the relative movement of blocks. 展开更多
关键词 中国 西南地区 地震 构造物理学 中新世
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Lushan M_S7.0 earthquake:A blind reserve-fault event 被引量:35
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作者 XU XiWei WEN XueZe +12 位作者 han zhujun CHEN GuiHua LI ChuanYou ZHENG WenJun ZHNAG ShiMin REN ZhiQun XU Chong TAN XiBin WEI ZhanYu WANG MingMing REN JunJie HE ZhongTai LIANG MingJian 《Chinese Science Bulletin》 SCIE EI CAS 2013年第28期3437-3443,共7页
In the epicenter of the Lushan MS7.0 earthquake there are several imbricate active reverse faults lying from northwest to southeast,namely the Gengda-Longdong,Yanjing-Wulong,Shuangshi-Dachuan and Dayi faults.Emergency... In the epicenter of the Lushan MS7.0 earthquake there are several imbricate active reverse faults lying from northwest to southeast,namely the Gengda-Longdong,Yanjing-Wulong,Shuangshi-Dachuan and Dayi faults.Emergency field investigations have indicated that no apparent earthquake surface rupture zones were located along these active faults or their adjacent areas.Only brittle compressive ruptures in the cement-covered pavements can be seen in Shuangshi,Taiping,Longxing and Longmen Townships,and these ruptures show that a local crustal shortening occurred in the region during the earthquake.Combining spatial distribution of the relocated aftershocks and focal mechanism solutions,it is inferred that the Lushan earthquake is classified as a typical blind reverse-fault earthquake,and it is advised that the relevant departments should pay great attention to other historically un-ruptured segments along the Longmenshan thrust belt and throughout its adjacent areas. 展开更多
关键词 地震地表破裂带 庐山 故障 事件 储备 邻近地区 震源机制解 地壳缩短
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NtLTP2基因在烟草根系发育中的功能分析
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作者 段史江 陈小龙 +7 位作者 梁周虹 王占伟 程小强 苏鹏飞 李亚纯 谢天琪 韩助君 杨永锋 《烟草科技》 CAS CSCD 北大核心 2023年第6期1-7,共7页
为阐明烟草NtLTP2基因在烟草生长发育中的功能,以云烟87为试验材料,克隆了NtLTP2基因的编码区和启动子序列,分别对其进行生物信息学预测、启动子组织驱动特性分析,以及基因功能研究。结果表明NtLTP2基因编码区全长294 bp,编码97个氨基酸... 为阐明烟草NtLTP2基因在烟草生长发育中的功能,以云烟87为试验材料,克隆了NtLTP2基因的编码区和启动子序列,分别对其进行生物信息学预测、启动子组织驱动特性分析,以及基因功能研究。结果表明NtLTP2基因编码区全长294 bp,编码97个氨基酸;NtLTP2具备nsLTP2和AAI-LTSS超家族保守域,蛋白质三级结构包含1个由4个α-螺旋组成的脂质疏水腔。烟草NtLTP2为根部优势表达基因,其启动子能够驱动下游基因在烟草根部特异表达。NtLTP2过表达烟草株系的侧根数目约为对照的2倍,根系的总长、总表面积和总体积均显著增加,并且地上部分的生长发育明显优于对照。 展开更多
关键词 烟草 NtLTP2 启动子 生物信息学 基因过表达
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左心室肌CT影像组学特征在心跳周期中动态变化的量化分析 被引量:1
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作者 苏铭 尹勇 +3 位作者 韩柱君 邱小平 仇清涛 巩贯忠 《中华放射医学与防护杂志》 CAS CSCD 北大核心 2020年第8期636-641,共6页
目的应用影像组学技术结合心电门控4DCT强化扫描图像,量化分析左心室肌CT影像组学特征在心动周期中的变化情况,为基于心电门控4DCT进行心脏功能动态评估提供可行方法。方法将14例患者的4DCT强化扫描图像以心动周期5%为间隔,重建0%~95%2... 目的应用影像组学技术结合心电门控4DCT强化扫描图像,量化分析左心室肌CT影像组学特征在心动周期中的变化情况,为基于心电门控4DCT进行心脏功能动态评估提供可行方法。方法将14例患者的4DCT强化扫描图像以心动周期5%为间隔,重建0%~95%20个时相的图像。分别在单个时相勾画左心室肌(LVM),并在左心室心腔造影剂充盈完好区域勾画直径为13 mm的球体[心腔感兴趣区(ROI)]。利用3DSlicer软件对所有勾画的92个特征进行提取,分析CT值在心腔ROI和LVM上的分布情况,基于心腔ROI进行初步筛选(单因素方差分析)得到稳定特征,再利用稳定特征对LVM进一步筛选(单因素方差分析)得到有差异特征,然后采用Wilcoxon秩和检验量化分析特征在心跳周期中随心跳的变化情况。结果心跳周期中心腔ROI的平均CT值变化率小于LVM,变化率分别为9.23%、17.88%。有36个稳定特征在心腔ROI上差异均无统计学意义(P>0.05);在36个稳定特征中,对LVM分析得到20个差异有统计学意义的特征(F=1.641~6.206,P<0.05),且平均变化率达到98.63%,其中Firstorder矩阵:中值(-103.96%)、均值(123.67%);GLDM矩阵:灰度非均匀性(99.81%)等变化率达到了99%以上,且不同心动周期中的最大值、最小值之间的差异均具有统计学意义(Z=-3.921^-3.173,P<0.05)。结论通过结合影像组学技术和心电门控4DCT强化扫描图像可以放大心动周期中CT图像的微观变化,可为左心室肌功能的变化评估提供一个新方法,Firstorder矩阵的均值等特征更具应用潜力。 展开更多
关键词 心动周期 心肌功能 评估 影像组学
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大体积肺癌IMRT初次及二次计划剂量学变化研究 被引量:3
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作者 任建新 尹勇 +4 位作者 巩贯忠 姚鑫森 韩柱君 苏铭 全红 《中华放射肿瘤学杂志》 CSCD 北大核心 2020年第10期872-876,共5页
目的采用刚性配准和形变配准方法获得大体积非小细胞肺癌(NSCLC)IMRT中靶区和危及器官(OAR)的累加剂量,并与初次计划的剂量进行比较。方法选择30例采用IMRT的大体积NSCLC患者,每位患者分别在放疗前和放疗20分次时进行4DCT模拟定位,基于... 目的采用刚性配准和形变配准方法获得大体积非小细胞肺癌(NSCLC)IMRT中靶区和危及器官(OAR)的累加剂量,并与初次计划的剂量进行比较。方法选择30例采用IMRT的大体积NSCLC患者,每位患者分别在放疗前和放疗20分次时进行4DCT模拟定位,基于初次4DCT的平均密度投影CT1-avg制定放疗计划为Plan1,基于二次4DCT的平均密度投影CT2-avg修改放疗计划为Plan2,分别采用刚性配准和形变配准方法将两次计划进行剂量累加得到Plan刚性和Plan形变。比较初次定位和二次定位之间大体肿瘤体积(GTV,以吸气末时相图像CT50%上的勾画为准)和OAR(OAR,以平均密度投影图像CTavg上的勾画为准)的体积变化,以及Plan2、Plan刚性、Plan形变的剂量体积指标相比Plan1的差异。结果二次定位和初次定位相比,GTV、心脏体积分别缩小44.2%、5.5%,患侧肺、健侧肺、全肺体积分别增大5.2%、6.2%、5.8%(P<0.05);对于内GTV(IGTV,10个4DCT时相的GTV融合而来)和计划靶体积(PTV)的D95%、D98%、V100%,Plan2与Plan1相近(P>0.05),Plan刚性、Plan形变较Plan1均略有下降(P<0.05);对于脊髓、心脏、患侧肺、双肺剂量,Plan2、Plan刚性、Plan形变较Plan1均降低(P<0.05),其中心脏V30Gy和Dmean分别降低27.3%、16.5%、15.3%和15.2%、6.6%、5.6%,双肺V20Gy和Dmean分别降低15.6%、4.5%、3.7%和15.7%、6.2%、5.1%;Plan形变的IGTV和PTV的D95%、D98%,心脏V40Gy,患侧肺和全肺的V20Gy、Dmean高于Plan刚性(P<0.05)。形变配准后OAR相似指数明显高于刚性配准(P<0.05)。结论Plan2中OAR剂量体积指标相比Plan1差别很大,因此它们在预测OAR放射性损伤方面均有较大偏差,而形变配准得到的剂量体积指标可以提高预测精度。 展开更多
关键词 肺肿瘤/调强放射疗法 形变配准 剂量学
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Fission track dating of the Cenozoic uplift in Mabian area, southern Sichuan Province, China 被引量:14
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作者 AN YanFen han zhujun WAN JingLin 《Science China Earth Sciences》 SCIE EI CAS 2008年第9期1238-1247,共10页
The apparent ages of samples are obtained from fission track dating of apatite samples collected from the fault zones in Mabian area, southern Sichuan Province. In addition, thermal history is simulated from the obtai... The apparent ages of samples are obtained from fission track dating of apatite samples collected from the fault zones in Mabian area, southern Sichuan Province. In addition, thermal history is simulated from the obtained data by applying AFT Solve Program, to acquire the thermal evolution history of the samples. The result shows that tectonically the Mabian area was relatively stable between 25 and 3 Ma, compared to the inner parts and other marginal areas of the Tibetan Plateau. The studied area had little response to the rapid uplift events that occurred for several times in the Tibetan Plateau during 25-3 Ma. The latest thermal event related to the activity of the Lidian fault zone (about 8 Ma ) is later than that of the Ebian fault zone (18-15 Ma ) to the west, indicating to some extent that the evolution of fault activity in the Mabian area has migrated from west to east. The latest extensive tectonic uplift occurred since about 3 Ma. As compared with the Xianshuihe fault zone, the Mabian area is closer to the east- ern margin of the plateau, while the time of fast cooling event in this area is later than that in the southeast segment of the Xianshuihe fault zone (3.6-3.46 Ma ). It appears to support the assumption of episodic uplift and stepwise outward extension of the eastern boundary of the Tibetan Plateau in late Cenozoic. 展开更多
关键词 Mabian area SOUTHERN SICHUAN Province APATITE FISSION track thermal history simulation UPLIFT fault activity
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Activity of the Lenglongling fault system and seismotectonics of the 2016 MS6.4 Menyuan earthquake 被引量:15
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作者 GUO Peng han zhujun +3 位作者 AN YanFen JIANG WenLiang MAO ZeBin FENG Wei 《Science China Earth Sciences》 SCIE EI CAS CSCD 2017年第5期929-942,共14页
The MS6.4 Menyuan earthquake occurred on the northern side of the Lenglongling fault(LLLF) in the mid-western of the Qilian-Haiyuan fault zone on January 21, 2016. The earthquake epicenter was distant from the Minle-D... The MS6.4 Menyuan earthquake occurred on the northern side of the Lenglongling fault(LLLF) in the mid-western of the Qilian-Haiyuan fault zone on January 21, 2016. The earthquake epicenter was distant from the Minle-Damaying and Huangcheng-Shuangta faults, eastern of the Northern Qilian Shan fault zone. A near northwest-striking rupture plane intersects the two faults at a certain angle. The focal mechanism solution shows that this was a thrust-type earthquake, slightly different from the strike-slip movement with a thrust component of the LLLF. Field geological mapping, tectonic geomorphology analysis, trench excavation and 14 C dating reveal that(1) the LLLF has been obviously active since the Holocene, and may behave with characteristic slip behavior and produce M_W7.3–7.5 earthquakes;(2) the LLLF appears as a flower structure in terms of structure style, and dips NNE at a steep angle; and(3) the most recent earthquake event occurred after 1815–1065 a BP. An associated fault, the Northern Lenglongling fault(NLLLF), is located at the northwestern end of the LLLF. Consequently, the NLLLF was continually subject to tectonic pushing effects from the left-lateral shear at the end of the LLLF, and, accordingly, it bent and rotated outward tectonically.Subsequently, the fault deviated from the dominant rupture azimuth and activity weakened. In the late Quaternary, it behaved as a thrust fault with no obvious deformation at the surface. This is indicated by the arc shape, with a micro-protrusion northeastward,and no geologic or geomorphic signs of surface rupturing since the late Quaternary. However, such faults could still rupture at depth, producing moderate-strong earthquakes. The geometric and kinematic properties of the NLLLF are in good agreement with the occurrence and kinematic properties of nodal plane 2, and with the distribution characteristics of the aftershocks and seismic intensity. Therefore, the NLLLF is a more suitable seismogenic structure for the MS 6.4 Menyuan earthquake. In addition, the thrust movement of the NLLLF accommodates subsequent movement of the LLLF. During the historical evolution of the NLLLF,the LLLF and the NLLLF have affected the local topography through tectonic uplift. 展开更多
关键词 构造地貌分析 地震活动 断裂体系 野外地质填图 逆冲断层 海原断裂带 走滑运动 表现特征
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Geological analysis and FT dating of the large-scale right-lateral strike-slip movement of the Red River fault zone 被引量:10
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作者 XIANG HongFa WAN JingLin +4 位作者 han zhujun GUO ShunMin ZhanG WanXia CHEN LiChun DONG XingQuan 《Science China Earth Sciences》 SCIE EI CAS 2007年第3期331-342,共12页
Tectonically, the large-scale right-lateral strike-slip movement along the Red River fault zone is char-acterized at its late phase with the southeastward extension and deformation of the Northwestern Yunnan normal fa... Tectonically, the large-scale right-lateral strike-slip movement along the Red River fault zone is char-acterized at its late phase with the southeastward extension and deformation of the Northwestern Yunnan normal fault depression on its northern segment, and the dextral shear displacement on its central-southern segment. Research of the relations between stratum deformation and fault movement on the typical fault segments, such as Jianchuan, southeast Midu, Yuanjiang River, Yuanyang, etc. since the Miocene Epoch shows that there are two times dextral faulting dominated by normal shearing occurring along the Red River fault zone since the Miocene Epoch. The fission track dating (abbrevi-ated to FT dating, the same below) is conducted on apatite samples collected from the above fault segments and relating to these movements. Based on the measured single grain’s age and the con-fined track length, we choose the Laslet annealing model to retrieve the thermal history of the samples, and the results show that the fault zone experienced two times obvious shear displacement, one in 5.5 ± 1.5 MaBP and the other in 2.1± 0.8 MaBP. The central-southern segment sees two intensive uplifts of mountain mass in the Yuanjiang River-Yuanyang region at 3.6―3.8 MaBP and 1.6―2.3 MaBP, which correspond to the above-mentioned two dextral normal displacement events since the late Miocene Epoch. 展开更多
关键词 GEOLOGICAL analysis FISSION track DATING the Red River fault dextral displacement TIMES
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