白木香为瑞香科沉香属植物,广泛分布于中国南部。中药沉香为该植物含树脂的木材,可用于循环系统疾病、腹痛、呕吐及呼吸困难等多种疾病的治疗。目前,已从白木香的叶、花以及含树脂的木材中分离并鉴定了249个单体化合物。现代药理研究表...白木香为瑞香科沉香属植物,广泛分布于中国南部。中药沉香为该植物含树脂的木材,可用于循环系统疾病、腹痛、呕吐及呼吸困难等多种疾病的治疗。目前,已从白木香的叶、花以及含树脂的木材中分离并鉴定了249个单体化合物。现代药理研究表明,白木香浸膏及其单体化合物具有抑制α-葡萄糖苷酶、抗炎、细胞毒性、神经保护、抗神经炎、抗菌和抑制乙酰胆碱酯酶等活性。此外,现代的分析色谱技术也被应用于该植物的质量控制研究,以确保其用药安全。本文对SciFinder、Web of Science、PubMed和谷歌学术等数据库中有关报道白木香植物化学、药理作用以及质量控制研究的文献进行了全面系统的总结和讨论,以期为充分利用该植物资源和阐明其药用物质基础提供理论参考。展开更多
Bletilla striata belongs to the family Orchidaceae,and it is mainly distributed in East Asia.The tubers of B.striata have been utilized in Traditional Chinese Medicine for various ailments,such as hematemesis,tubercul...Bletilla striata belongs to the family Orchidaceae,and it is mainly distributed in East Asia.The tubers of B.striata have been utilized in Traditional Chinese Medicine for various ailments,such as hematemesis,tuberculosis,malignant ulcers,hemorrhoids,traumatic bleeding,and chapped skin.Phytochemical investigation on B.striata has resulted in the identification of 192 monomeric compounds,including bibenzyls,phenanthrene derivatives,triterpenoids and its saponins,steroids and its saponins,malic acid derivatives,and anthocyanins.Moreover,B.striata polysaccharide is another typical chemical constituent of this plant.Pharmacology studies have shown that the plant possesses wound healing,antimicrobial,anticancer,antioxidative,and antiviral activities.This review aims to provide the latest and comprehensive information on chemical constituents,pharmacological activities,and quality control of B.striata and to identify future research needs.展开更多
基金funding support from the Key Laboratory For Quality Evaluation of Bulk Herbs of Hunan Province and national science foundation of China (No.81374062 and No.81673579)
基金funding support from Hunan Province Universities 2011 Collaborative Innovation Center of Protection and Utilization of Huxiang Chinese Medicine Resources, Hunan Provincial Key Laboratory of Diagnostics in Chinese Medicine, and National Natural Science Foundation of China (No. 81673579)
基金support from the Administration of Traditional Chinese Medicine of Hunan Province(201673)Hunan Province Universities 2011 Collaborative Innovation Center of Protection and Utilization of Hu-xiang Chinese Medicine Resources(HXZY-2015-005 and HXZY-2015-012)+1 种基金the State Key Subject of TCM Diagnostics in Hunan University of Chinese Medicine(2015ZYZD06)Hunan Provincial Key Laboratory of Dong Medicine(2015TP1020-02)
文摘白木香为瑞香科沉香属植物,广泛分布于中国南部。中药沉香为该植物含树脂的木材,可用于循环系统疾病、腹痛、呕吐及呼吸困难等多种疾病的治疗。目前,已从白木香的叶、花以及含树脂的木材中分离并鉴定了249个单体化合物。现代药理研究表明,白木香浸膏及其单体化合物具有抑制α-葡萄糖苷酶、抗炎、细胞毒性、神经保护、抗神经炎、抗菌和抑制乙酰胆碱酯酶等活性。此外,现代的分析色谱技术也被应用于该植物的质量控制研究,以确保其用药安全。本文对SciFinder、Web of Science、PubMed和谷歌学术等数据库中有关报道白木香植物化学、药理作用以及质量控制研究的文献进行了全面系统的总结和讨论,以期为充分利用该植物资源和阐明其药用物质基础提供理论参考。
文摘Bletilla striata belongs to the family Orchidaceae,and it is mainly distributed in East Asia.The tubers of B.striata have been utilized in Traditional Chinese Medicine for various ailments,such as hematemesis,tuberculosis,malignant ulcers,hemorrhoids,traumatic bleeding,and chapped skin.Phytochemical investigation on B.striata has resulted in the identification of 192 monomeric compounds,including bibenzyls,phenanthrene derivatives,triterpenoids and its saponins,steroids and its saponins,malic acid derivatives,and anthocyanins.Moreover,B.striata polysaccharide is another typical chemical constituent of this plant.Pharmacology studies have shown that the plant possesses wound healing,antimicrobial,anticancer,antioxidative,and antiviral activities.This review aims to provide the latest and comprehensive information on chemical constituents,pharmacological activities,and quality control of B.striata and to identify future research needs.
