目的分析突聋患者的内耳钆造影MRI三维真实重建反转恢复(three dimensional real inversion recovery,3D real IR)成像上的表现,探讨血-迷路屏障的通透性与突聋发病机制及其预后的关系。方法对41例单侧突聋患者行内耳钆造影MRI,测量患...目的分析突聋患者的内耳钆造影MRI三维真实重建反转恢复(three dimensional real inversion recovery,3D real IR)成像上的表现,探讨血-迷路屏障的通透性与突聋发病机制及其预后的关系。方法对41例单侧突聋患者行内耳钆造影MRI,测量患耳和健耳的耳蜗信号强度,并测量延髓信号强度,分别计算出耳蜗/延髓比值(cochlear/medulla ratio,CM ratio),以CM比值作为血-迷路屏障通透性的标志物,分析突聋患者患耳、健耳CM比值的不对称程度与疗效之间的关系。结果41例患者中,33例(80.48%)患耳的CM比值高于健耳,差异有统计学意义(P<0.05);患耳CM比值为健耳的1.5倍以下者18例,治疗有效率为77.78%(14/18);患侧CM比值不高于健侧者8例,治疗有效率为100%;达到健耳的1.5倍至1.75倍之间者7例,治疗有效率为100%(7/7);达到健耳的1.75倍至2.0倍之间者2例,治疗有效率为50%(1/2);达到健耳的2.0倍以上者14例,治疗有效率为14.28%(12/14);差异有统计学意义(P<0.05)。结论内耳3D Real IR可显示突聋患者血-迷路屏障通透性的改变,80.48%的突聋患者患侧耳蜗出现高信号,患耳CM比值达健耳的1.75倍以上者多数预后不良。展开更多
The demand for high-data-rate underwater acoustic communications(UACs)in marine development is increasing;however,severe multipaths make demodulation a challenge.The decision feedback equalizer(DFE)is one of the most ...The demand for high-data-rate underwater acoustic communications(UACs)in marine development is increasing;however,severe multipaths make demodulation a challenge.The decision feedback equalizer(DFE)is one of the most popular equalizers in UAC;however,it is not the optimal algorithm.Although maximum likelihood sequence estimation(MLSE)is the optimal algorithm,its complexity increases exponentially with the number of channel taps,making it challenging to apply to UAC.Therefore,this paper proposes a complexity-reduced MLSE to improve the bit error rate(BER)performance in multipath channels.In the proposed algorithm,the original channel is first shortened using a channel-shortening method,and several dominant channel taps are selected for MLSE.Subsequently,sphere decoding(SD)is performed in the following MLSE.Iterations are applied to eliminate inter-symbol interference caused by weak channel taps.The simulation and sea experiment demonstrate the superiority of the proposed algorithm.The simulation results show that channel shortening combined with SD can drastically reduce computational complexity,and iterative SD performs better than DFE based on recursive least squares(RLS-DFE),DFE based on improved proportionate normalized least mean squares(IPNLMS-DFE),and channel estimation-based DFE(CE-DFE).Moreover,the sea experimental results at Zhairuoshan Island in Zhoushan show that the proposed receiver scheme has improved BER performance over RLSDFE,IPNLMS-DFE,and CE-DFE.Compared with the RLS-DFE,the BER,after five iterations,is reduced from 0.0076 to 0.0037 in the 8–12 k Hz band and from 0.1516 to 0.1145 in the 13–17 k Hz band at a distance of 2000 m.Thus,the proposed algorithm makes it possible to apply MLSE in UAC in practical scenarios.展开更多
文摘目的分析突聋患者的内耳钆造影MRI三维真实重建反转恢复(three dimensional real inversion recovery,3D real IR)成像上的表现,探讨血-迷路屏障的通透性与突聋发病机制及其预后的关系。方法对41例单侧突聋患者行内耳钆造影MRI,测量患耳和健耳的耳蜗信号强度,并测量延髓信号强度,分别计算出耳蜗/延髓比值(cochlear/medulla ratio,CM ratio),以CM比值作为血-迷路屏障通透性的标志物,分析突聋患者患耳、健耳CM比值的不对称程度与疗效之间的关系。结果41例患者中,33例(80.48%)患耳的CM比值高于健耳,差异有统计学意义(P<0.05);患耳CM比值为健耳的1.5倍以下者18例,治疗有效率为77.78%(14/18);患侧CM比值不高于健侧者8例,治疗有效率为100%;达到健耳的1.5倍至1.75倍之间者7例,治疗有效率为100%(7/7);达到健耳的1.75倍至2.0倍之间者2例,治疗有效率为50%(1/2);达到健耳的2.0倍以上者14例,治疗有效率为14.28%(12/14);差异有统计学意义(P<0.05)。结论内耳3D Real IR可显示突聋患者血-迷路屏障通透性的改变,80.48%的突聋患者患侧耳蜗出现高信号,患耳CM比值达健耳的1.75倍以上者多数预后不良。
基金Supported by the National Natural Science Foundation of China under Grant Nos. 62101489, 62171405 and 62225114.
文摘The demand for high-data-rate underwater acoustic communications(UACs)in marine development is increasing;however,severe multipaths make demodulation a challenge.The decision feedback equalizer(DFE)is one of the most popular equalizers in UAC;however,it is not the optimal algorithm.Although maximum likelihood sequence estimation(MLSE)is the optimal algorithm,its complexity increases exponentially with the number of channel taps,making it challenging to apply to UAC.Therefore,this paper proposes a complexity-reduced MLSE to improve the bit error rate(BER)performance in multipath channels.In the proposed algorithm,the original channel is first shortened using a channel-shortening method,and several dominant channel taps are selected for MLSE.Subsequently,sphere decoding(SD)is performed in the following MLSE.Iterations are applied to eliminate inter-symbol interference caused by weak channel taps.The simulation and sea experiment demonstrate the superiority of the proposed algorithm.The simulation results show that channel shortening combined with SD can drastically reduce computational complexity,and iterative SD performs better than DFE based on recursive least squares(RLS-DFE),DFE based on improved proportionate normalized least mean squares(IPNLMS-DFE),and channel estimation-based DFE(CE-DFE).Moreover,the sea experimental results at Zhairuoshan Island in Zhoushan show that the proposed receiver scheme has improved BER performance over RLSDFE,IPNLMS-DFE,and CE-DFE.Compared with the RLS-DFE,the BER,after five iterations,is reduced from 0.0076 to 0.0037 in the 8–12 k Hz band and from 0.1516 to 0.1145 in the 13–17 k Hz band at a distance of 2000 m.Thus,the proposed algorithm makes it possible to apply MLSE in UAC in practical scenarios.
