Head and neck cancer and the approaches used to treat it can cause symptoms such as mucositis,alteration or loss of taste,dysphagia,and xerostomia,whichmakes the incidence of malnutrition in head and neck cancer patie...Head and neck cancer and the approaches used to treat it can cause symptoms such as mucositis,alteration or loss of taste,dysphagia,and xerostomia,whichmakes the incidence of malnutrition in head and neck cancer patients higher than in the general population of cancer patients.Malnutrition in patients with head and neck cancer is associated with the occurrence of treatment-related adverse events,an increase in overall economic cost,a decline in quality of life,and a poor prognosis.Therefore,rehabilitation interventions for malnutrition are necessary throughout the course of the disease.However,the importance of rehabilitation interventions for malnutrition in patients with head and neck cancer has not been fully recognized,and the optimal methods and timing of interventions are unclear.This article provides an overview of rehabilitation interventions for malnutrition,including nutritional supplementation,exercise-based interventions,nutritional counseling and cognitive improvement,and drug therapy,and discusses their advantages and disadvantages as well as potential future directions.展开更多
Germanium-based material has attracted numerous attentions and been regarded as a promising anode material for lithium-ion batteries due to its high theoretical capacity.However,drastic pulverization and rapid capacit...Germanium-based material has attracted numerous attentions and been regarded as a promising anode material for lithium-ion batteries due to its high theoretical capacity.However,drastic pulverization and rapid capacity fading caused by large volume variation during cycling limit its practical application.In this work,three-dimensional N-doped carbon framework-wrapped Na_(4)Ge_(9)O_(20)nanoparticles(3D Na_(4)Ge_(9)O_(20)@N-C)have been synthesized via freeze-drying approach with NaCl as both template and sodium source for ion-exchanging.The employment of NaCl has two special roles:on the one hand,the NaCl crystals act as template and facilitate the formation of 3D porous structure,while on the other hand,the NaCl crystals serving as sodium source and support the ion exchange between NaCl and GeO_(2)promote the formation of Na_(4)Ge_(9)O_(20).Benefiting from the unique method,the prepared 3D Na_(4)Ge_(9)O_(20)@N-C not only suppresses the volume change by using carbon as buffer layers but also demonstrates an improved electronic conductivity and a shortened ionic diffusion.When utilized as an anode material for LIBs,the 3D Na_(4)Ge_(9)O_(20)@N-C composites deliver high reversible capacity(896.2 mAh·g^(-1)at0.1 A·g^(-1)after 100 cycles),good cycling stability(520.8 mAh·g^(-1)at 2.0 A·g^(-1)after 400 cycles)and excellent rate performance(636.0 mAh·g^(-1)at 2.0 A·g^(-1)).This work provides a strategy to improve the electrochemical performance of germanium-based anode materials for lithium-ion batteries.展开更多
文摘Head and neck cancer and the approaches used to treat it can cause symptoms such as mucositis,alteration or loss of taste,dysphagia,and xerostomia,whichmakes the incidence of malnutrition in head and neck cancer patients higher than in the general population of cancer patients.Malnutrition in patients with head and neck cancer is associated with the occurrence of treatment-related adverse events,an increase in overall economic cost,a decline in quality of life,and a poor prognosis.Therefore,rehabilitation interventions for malnutrition are necessary throughout the course of the disease.However,the importance of rehabilitation interventions for malnutrition in patients with head and neck cancer has not been fully recognized,and the optimal methods and timing of interventions are unclear.This article provides an overview of rehabilitation interventions for malnutrition,including nutritional supplementation,exercise-based interventions,nutritional counseling and cognitive improvement,and drug therapy,and discusses their advantages and disadvantages as well as potential future directions.
基金financially supported by the National Natural Science Foundation of China(No.51874362)the Scientific Research Project of Hunan Provincial Department of Education(No.21B0815)。
文摘Germanium-based material has attracted numerous attentions and been regarded as a promising anode material for lithium-ion batteries due to its high theoretical capacity.However,drastic pulverization and rapid capacity fading caused by large volume variation during cycling limit its practical application.In this work,three-dimensional N-doped carbon framework-wrapped Na_(4)Ge_(9)O_(20)nanoparticles(3D Na_(4)Ge_(9)O_(20)@N-C)have been synthesized via freeze-drying approach with NaCl as both template and sodium source for ion-exchanging.The employment of NaCl has two special roles:on the one hand,the NaCl crystals act as template and facilitate the formation of 3D porous structure,while on the other hand,the NaCl crystals serving as sodium source and support the ion exchange between NaCl and GeO_(2)promote the formation of Na_(4)Ge_(9)O_(20).Benefiting from the unique method,the prepared 3D Na_(4)Ge_(9)O_(20)@N-C not only suppresses the volume change by using carbon as buffer layers but also demonstrates an improved electronic conductivity and a shortened ionic diffusion.When utilized as an anode material for LIBs,the 3D Na_(4)Ge_(9)O_(20)@N-C composites deliver high reversible capacity(896.2 mAh·g^(-1)at0.1 A·g^(-1)after 100 cycles),good cycling stability(520.8 mAh·g^(-1)at 2.0 A·g^(-1)after 400 cycles)and excellent rate performance(636.0 mAh·g^(-1)at 2.0 A·g^(-1)).This work provides a strategy to improve the electrochemical performance of germanium-based anode materials for lithium-ion batteries.
