期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
A finTRIM member 100 (FTR100) is unique to Otomorpha fish for constitutive regulation of IFN response
1
作者 Wen-Hao Guo Cheng Dan +8 位作者 Xiu-Ying Gong Yi-Lin Li hao-yu sun Zi-Ling Qu Li-Li An Xiang Zhao Jie Mei Jian-Fang Gui Yi-Bing Zhang 《Water Biology and Security》 2023年第2期80-90,共11页
Vertebrate interferon(IFN)expression is fine-tuned in order to avoid excessive tissue injury under normal conditions and during virus infection.FinTRIM(fish novel TRIM,FTR)proteins are reported to regulate the fish IF... Vertebrate interferon(IFN)expression is fine-tuned in order to avoid excessive tissue injury under normal conditions and during virus infection.FinTRIM(fish novel TRIM,FTR)proteins are reported to regulate the fish IFN response.Here,we identify a novel finTRIM gene from yellow catfish(Pelteobagrus fulvidraco),which is sequentially named PfFTR100 according to the nomenclature rule in zebrafish.Genome-wide analyses reveal that FTR100 is unique to Otomorpha fish,with a single copy in spite of additional genome duplication in some fish species.Considering that few of the 99 finTRIM genes identified in zebrafish are conserved in main fish branches and most,such as FTR100,are unique to distinct branches due to lineage-specific expansion of finTRIM genes,we develop a nomenclature for newly cloned finTRIM genes from different fish species.PfFTR100 mRNA is not induced by virus infection,with a relatively high expression level comparable to that of cellular IFN and some IFN-stimulated genes(ISGs)in virally-infected tissues.However,ectopically-expressed PfFTR100 protein is attenuated in virally-infected cells through the proteasomal-dependent pathway.Overexpression of PfFTR100 promotes SVCV replication by downregulating the constitutive and inducible IFN response via a mechanism by which PfFTR100 targets IRF3 and IRF7 to attenuate their mRNA levels rather than their protein levels.Our results indicate that yellow catfish FTR100 is essential for homeostatic regulation of fish tonic IFN response. 展开更多
关键词 Constitutive expression FTR100 Homeostatic regulation Lineage-specific expansion Tonic IFN response
原文传递
ScQ cloud quantum computation for generating Greenberger-Horne-Zeilinger states of up to 10 qubits
2
作者 Chi-Tong Chen Yun-Hao Shi +9 位作者 Zhongcheng Xiang Zheng-An Wang Tian-Ming Li hao-yu sun Tian-Shen He Xiaohui Song Shiping Zhao Dongning Zheng Kai Xu Heng Fan 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS CSCD 2022年第11期84-89,共6页
In this study, we introduce an online public quantum computation platform, named as ScQ, based on a 1D array of a 10-qubit superconducting processor. Single-qubit rotation gates can be performed on each qubit. Control... In this study, we introduce an online public quantum computation platform, named as ScQ, based on a 1D array of a 10-qubit superconducting processor. Single-qubit rotation gates can be performed on each qubit. Controlled-NOT gates between nearest-neighbor sites on the 1D array of 10 qubits are available. We show the online preparation and verification of Greenberger-Horne-Zeilinger states of up to 10 qubits through this platform for all possible blocks of qubits in the chain. The graphical user interface and quantum assembly language methods are presented to achieve the above tasks, which rely on a parameter scanning feature implemented on ScQ. The performance of this quantum computation platform, such as fidelities of logic gates and details of the superconducting device, is presented. 展开更多
关键词 quantum computation quantum information quantum entanglement
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部