Summary What is already known about this topic?Thallium(Tl)is significantly more toxic than heavy metals such as lead,cadmium,and mercury.However,previous studies examining the relationship between Tl exposure and the...Summary What is already known about this topic?Thallium(Tl)is significantly more toxic than heavy metals such as lead,cadmium,and mercury.However,previous studies examining the relationship between Tl exposure and the risk of chronic kidney disease(CKD)have yielded inconsistent results.What is added by this report?展开更多
What is already known about this topic?Environmental and occupational lead exposure has generally declined in the past two decades.However,there is no large-scale monitoring of blood lead levels(BLLs)in the Chinese ge...What is already known about this topic?Environmental and occupational lead exposure has generally declined in the past two decades.However,there is no large-scale monitoring of blood lead levels(BLLs)in the Chinese general population.What is added by this report?This nationally representative study showed declines of BLLs in all ages of participants;for children aged 3–5 years,down from 78.1μg/L to 16.9μg/L,corresponding to 78.4%decrease in the past two decades(2000–2018).What are the implications for public health practice?Recommendations for elevated BLLs on screening children at high risk now need to be revisited and updated from 100μg/L to 50μg/L in guidelines to conform with the substantial declines in China.展开更多
基金Supported by the National Key Research and Development Program of China(2022YFA0806600)the National Natural Science Foundation of China(81941023).
文摘Summary What is already known about this topic?Thallium(Tl)is significantly more toxic than heavy metals such as lead,cadmium,and mercury.However,previous studies examining the relationship between Tl exposure and the risk of chronic kidney disease(CKD)have yielded inconsistent results.What is added by this report?
基金supported by National Health Commission of the People's Republic of China,the National Institute of Environmental Health of Chinese Center for Disease Control and Prevention,and National Natural Sciences Foundation of China(81872707).
文摘What is already known about this topic?Environmental and occupational lead exposure has generally declined in the past two decades.However,there is no large-scale monitoring of blood lead levels(BLLs)in the Chinese general population.What is added by this report?This nationally representative study showed declines of BLLs in all ages of participants;for children aged 3–5 years,down from 78.1μg/L to 16.9μg/L,corresponding to 78.4%decrease in the past two decades(2000–2018).What are the implications for public health practice?Recommendations for elevated BLLs on screening children at high risk now need to be revisited and updated from 100μg/L to 50μg/L in guidelines to conform with the substantial declines in China.