CONSPECTUS:Sonodynamic therapy(SDT)is a noninvasive and more preferable therapeutic modality than photodynamic therapy(PDT)due to deeper tissue penetration,which utilizes sonosensitizers to produce reactive oxygen spe...CONSPECTUS:Sonodynamic therapy(SDT)is a noninvasive and more preferable therapeutic modality than photodynamic therapy(PDT)due to deeper tissue penetration,which utilizes sonosensitizers to produce reactive oxygen species(ROS)to kill tumor cells and arouse immune responses.However,it still suffers from low ROS production efficiency and insufficient systematic immune activation,which thus has attracted increasing attention and researchers to engage in this field.展开更多
基金supported by the National Outstanding Youth Science Fund Project of the National Natural Science Foundation of China(Grant No.82022033)the Shanghai Rising-Star Program(Grant No.19QA1406800)+2 种基金the Shanghai Talent Development Fund(Grant No.2019040)the Fundamental Research Funds for the Central Universities(22120210561)the program for Shanghai Young Top-Notch Talent.
文摘CONSPECTUS:Sonodynamic therapy(SDT)is a noninvasive and more preferable therapeutic modality than photodynamic therapy(PDT)due to deeper tissue penetration,which utilizes sonosensitizers to produce reactive oxygen species(ROS)to kill tumor cells and arouse immune responses.However,it still suffers from low ROS production efficiency and insufficient systematic immune activation,which thus has attracted increasing attention and researchers to engage in this field.