China consumes significant amount of natural gas in winter.The integrated community energy utilization system(ICEUS)cannot stabilize the output of electricity and heat if there is a shortage of natural gas.The operati...China consumes significant amount of natural gas in winter.The integrated community energy utilization system(ICEUS)cannot stabilize the output of electricity and heat if there is a shortage of natural gas.The operation cost of the system still needs improvement.An energy supply structure using garbage power as the core of ICEUS was established in the study.The optimal dispatchingmodel of ICEUS was established using the regulating characteristic of the community load.The sine-cosine algorithm(SCA)based on nonlinear factors and segmented weight was presented to solve the optimal dispatching model of ICEUS.From the simulation results,compared with particle swarm optimization algorithm(PSO),SCA,exponential sinecosine algorithm(ESCA),and parabolic sine-cosine algorithm(PSCA),the daily operation cost of ICEUS was reduced by the improved SCA by 4.4%,2.9%,2.6%and 4.1%,respectively,in winter.The same was true in summer.The daily system operating cost was effectively reduced by the algorithm proposed in the study.The cost benefits of the optimized ICEUS operation was realized.展开更多
Undesirable self-excited chatter has always been a typical issue restricting the improvement of robotic milling quality and efficiency.Sensitive chatter identification based on processing signals can prompt operators ...Undesirable self-excited chatter has always been a typical issue restricting the improvement of robotic milling quality and efficiency.Sensitive chatter identification based on processing signals can prompt operators to adjust the machining process and prevent chatter damage.Compared with the traditional machine tool,the uncertain multiple chatter frequency bands and the band-moving of the chatter frequency in robotic milling process make it more challenging to extract chatter information.This paper proposes a novel method of chatter identification using optimized variational mode decomposition(OVMD)with multi-band information fusion and compression technology(MT).During the robotic milling process,the number of decomposed modes k and the penalty coefficient a are optimized based on the dominant component of frequency scope partition and fitness of the mode center frequency.Moreover,the mayfly optimization algorithm(MA)is employed to obtain the global optimal parameter selection.In order to conquer information collection about the uncertain multiple chatter frequency bands and the band-moving of the chatter frequency in robotic milling process,MT is presented to reduce computation and extract signal characteristics.Finally,the cross entropy of the image(CEI)is proposed as the final chatter indicator to identify the chatter occurrence.The robotic milling experiments are carried out to verify the proposed method,and the results show that it can distinguish the robotic milling condition by extracting the uncertain multiple chatter frequency bands and overcome the band-moving of the chatter frequency in robotic milling process.展开更多
In order to fully understand the research progress of human factors and traffic safety in curve driving,from the perspective of driver-vehicle-road-environment dynamic traffic system,this paper explored the current re...In order to fully understand the research progress of human factors and traffic safety in curve driving,from the perspective of driver-vehicle-road-environment dynamic traffic system,this paper explored the current research status and development trend of human factors of curve driving,and displayed the development process and structural relationship of human factors research of curve driving by using scientific knowledge map.Through the core collection database of Web of Science,1408 English literatures related to human factors research of curve driving published from 2012 to 2022(as of October 1,2022)were obtained,and the literatures in this field were sorted and analyzed based on the VOSviewer visualization software.The results show that China,Tongji University and Accident Analysis and Prevention are the country,institution and journal with the largest contribution rate in the field of human factors research on curve driving.Co-citation analysis shows that the research contents in this field are divided into 5 clusters:driver’s visual characteristics,risk of collision,vehicle dynamics characteristics,the influence of traffic engineering facilities on driving behavior,selection of driving speed.The co-occurrence analysis of keywords shows that the topics of curve geometry design and vehicle dynamics,driving behavior and risk,driving speed and safety,behavior prediction and intervention measures are the current research hotspots in the research field.It is found that the development trend of traffic safety improvement in curves is to construct a continuous,consistent,multi-level visual reference frame conforming to driving expectation through visual guiding technology,and summarizes the technical concept of linear visual guidance.This study can provide a reference for the study of human factors of curve driving.展开更多
Atomically precise gold nanoclusters(Au NCs) are an emerging class of quantum-sized nanomaterials with discrete electronic energy levels, which has led to a range of attractive electronic and optical applications. Nev...Atomically precise gold nanoclusters(Au NCs) are an emerging class of quantum-sized nanomaterials with discrete electronic energy levels, which has led to a range of attractive electronic and optical applications. Nevertheless, the lack of general methods to transfer Au NCs protected with hydrophobic ligands to an aqueous solution hampers their use in physiological settings. Here,we developed a single-stranded DNA-based approach that could transfer ~90% hydrophobic Au NCs into an aqueous solution.We experimentally and theoretically established that multivalent electrostatic and hydrophobic interactions between DNA strands and the hydrophobic ligand layer on Au NCs resulted in monodispersed DNA-coated Au NCs with high physical integrity in an aqueous solution. The fluorescence quantum yield of Au NCs was increased by ~13 fold, and surface-constrained DNA retained the specific recognition ability for biosensing. We further demonstrated the versatility of this phase-transfer approach, which thus holds great potential to advance biological and medical applications of Au NCs.展开更多
Background Healthy plasma therapy reverses cognitive deficits and promotes neuroplasticity in ageing brain disease.However,whether healthy plasma therapy improve blood-brain barrier integrity after stroke remains unkn...Background Healthy plasma therapy reverses cognitive deficits and promotes neuroplasticity in ageing brain disease.However,whether healthy plasma therapy improve blood-brain barrier integrity after stroke remains unknown.Methods Here,we intravenously injected healthy female mouse plasma into adult female ischaemic stroke C57BL/6 mouse induced by 90 min transient middle cerebral artery occlusion for eight consecutive days.Infarct volume,brain atrophy and neurobehavioural tests were examined to assess the outcomes of plasma treatment.Cell apoptosis,blood-brain barrier integrity and fibroblast growth factor 21 knockout mice were used to explore the underlying mechanism.Results Plasma injection improved neurobehavioural recovery and decreased infarct volume,brain oedema and atrophy after stroke.Immunostaining showed that the number of transferase dUTP nick end labelling+/NeuN+cells decreased in the plasma-injected group.Meanwhile,plasma injection reduced ZO-1,occluding and claudin-5 tight junction gap formation and IgG extravasation at 3 days after ischaemic stroke.Western blot results showed that the FGF21 expression increased in the plasma-injected mice.However,using FGF21 knockout mouse plasma injecting to the ischaemic wild-type mice diminished the neuroprotective effects.Conclusions Our study demonstrated that healthy adult plasma treatment protected the structural and functional integrity of blood-brain barrier,reduced neuronal apoptosis and improved functional recovery via FGF21,opening a new avenue for ischaemic stroke therapy.展开更多
基金The work is funded partly by the Natural Science Foundation of Inner Mongolia(2019MS05047)Key Technology Projects of Inner Mongolia Autonomous Region(2019GG319)Research on Key Technologies of MW advanced flywheel energy storage(2020ZD0017).
文摘China consumes significant amount of natural gas in winter.The integrated community energy utilization system(ICEUS)cannot stabilize the output of electricity and heat if there is a shortage of natural gas.The operation cost of the system still needs improvement.An energy supply structure using garbage power as the core of ICEUS was established in the study.The optimal dispatchingmodel of ICEUS was established using the regulating characteristic of the community load.The sine-cosine algorithm(SCA)based on nonlinear factors and segmented weight was presented to solve the optimal dispatching model of ICEUS.From the simulation results,compared with particle swarm optimization algorithm(PSO),SCA,exponential sinecosine algorithm(ESCA),and parabolic sine-cosine algorithm(PSCA),the daily operation cost of ICEUS was reduced by the improved SCA by 4.4%,2.9%,2.6%and 4.1%,respectively,in winter.The same was true in summer.The daily system operating cost was effectively reduced by the algorithm proposed in the study.The cost benefits of the optimized ICEUS operation was realized.
基金supported by the Civil Aircraft Project(No.MJZ4-1N22),National Natural Science Foundation of China(No.51975053)Inversion and Application Project of Outcome(Nos.D44F9A65 and 2B0188E1)+1 种基金Key R&D Program of Inner Mongolia(No.2022YFHH0121)the Basic Research Fund of Beijing Institute of Technology(No.2021CX01023).
文摘Undesirable self-excited chatter has always been a typical issue restricting the improvement of robotic milling quality and efficiency.Sensitive chatter identification based on processing signals can prompt operators to adjust the machining process and prevent chatter damage.Compared with the traditional machine tool,the uncertain multiple chatter frequency bands and the band-moving of the chatter frequency in robotic milling process make it more challenging to extract chatter information.This paper proposes a novel method of chatter identification using optimized variational mode decomposition(OVMD)with multi-band information fusion and compression technology(MT).During the robotic milling process,the number of decomposed modes k and the penalty coefficient a are optimized based on the dominant component of frequency scope partition and fitness of the mode center frequency.Moreover,the mayfly optimization algorithm(MA)is employed to obtain the global optimal parameter selection.In order to conquer information collection about the uncertain multiple chatter frequency bands and the band-moving of the chatter frequency in robotic milling process,MT is presented to reduce computation and extract signal characteristics.Finally,the cross entropy of the image(CEI)is proposed as the final chatter indicator to identify the chatter occurrence.The robotic milling experiments are carried out to verify the proposed method,and the results show that it can distinguish the robotic milling condition by extracting the uncertain multiple chatter frequency bands and overcome the band-moving of the chatter frequency in robotic milling process.
基金supported by the National Natural Science Foundation of China(Grant No.52072291)。
文摘In order to fully understand the research progress of human factors and traffic safety in curve driving,from the perspective of driver-vehicle-road-environment dynamic traffic system,this paper explored the current research status and development trend of human factors of curve driving,and displayed the development process and structural relationship of human factors research of curve driving by using scientific knowledge map.Through the core collection database of Web of Science,1408 English literatures related to human factors research of curve driving published from 2012 to 2022(as of October 1,2022)were obtained,and the literatures in this field were sorted and analyzed based on the VOSviewer visualization software.The results show that China,Tongji University and Accident Analysis and Prevention are the country,institution and journal with the largest contribution rate in the field of human factors research on curve driving.Co-citation analysis shows that the research contents in this field are divided into 5 clusters:driver’s visual characteristics,risk of collision,vehicle dynamics characteristics,the influence of traffic engineering facilities on driving behavior,selection of driving speed.The co-occurrence analysis of keywords shows that the topics of curve geometry design and vehicle dynamics,driving behavior and risk,driving speed and safety,behavior prediction and intervention measures are the current research hotspots in the research field.It is found that the development trend of traffic safety improvement in curves is to construct a continuous,consistent,multi-level visual reference frame conforming to driving expectation through visual guiding technology,and summarizes the technical concept of linear visual guidance.This study can provide a reference for the study of human factors of curve driving.
基金supported by the National Key R&D Program of China (2020YFA0908104)the National Natural Science Foundation of China (91953106, 92056117, 21904087, 21705159)+1 种基金the Shanghai Municipal Science and Technology Commission (19JC1410300,19ZR1474600, 20dz1101000, 21QA1404800)the Fundamental Research Funds for the Central Universities and Shanghai Jiao Tong University。
文摘Atomically precise gold nanoclusters(Au NCs) are an emerging class of quantum-sized nanomaterials with discrete electronic energy levels, which has led to a range of attractive electronic and optical applications. Nevertheless, the lack of general methods to transfer Au NCs protected with hydrophobic ligands to an aqueous solution hampers their use in physiological settings. Here,we developed a single-stranded DNA-based approach that could transfer ~90% hydrophobic Au NCs into an aqueous solution.We experimentally and theoretically established that multivalent electrostatic and hydrophobic interactions between DNA strands and the hydrophobic ligand layer on Au NCs resulted in monodispersed DNA-coated Au NCs with high physical integrity in an aqueous solution. The fluorescence quantum yield of Au NCs was increased by ~13 fold, and surface-constrained DNA retained the specific recognition ability for biosensing. We further demonstrated the versatility of this phase-transfer approach, which thus holds great potential to advance biological and medical applications of Au NCs.
基金This study was supported by grants from the Scientific Research and Innovation Program of Shanghai Education Commission 2019-01-07-00-02-E00064(G-YY)National Key R&D,Program of China#2016YFC1300602(G-YY),#2019YFA0112000(YT)+1 种基金the National Natural Science Foundation of China(NSFC)projects 81771251(G-YY),81801170(YT),82071284(YT),81771244(ZZ),81974179(ZZ),81870921(YW)K.C.Wong Education Foundation(G-YY,no award/grant number).
文摘Background Healthy plasma therapy reverses cognitive deficits and promotes neuroplasticity in ageing brain disease.However,whether healthy plasma therapy improve blood-brain barrier integrity after stroke remains unknown.Methods Here,we intravenously injected healthy female mouse plasma into adult female ischaemic stroke C57BL/6 mouse induced by 90 min transient middle cerebral artery occlusion for eight consecutive days.Infarct volume,brain atrophy and neurobehavioural tests were examined to assess the outcomes of plasma treatment.Cell apoptosis,blood-brain barrier integrity and fibroblast growth factor 21 knockout mice were used to explore the underlying mechanism.Results Plasma injection improved neurobehavioural recovery and decreased infarct volume,brain oedema and atrophy after stroke.Immunostaining showed that the number of transferase dUTP nick end labelling+/NeuN+cells decreased in the plasma-injected group.Meanwhile,plasma injection reduced ZO-1,occluding and claudin-5 tight junction gap formation and IgG extravasation at 3 days after ischaemic stroke.Western blot results showed that the FGF21 expression increased in the plasma-injected mice.However,using FGF21 knockout mouse plasma injecting to the ischaemic wild-type mice diminished the neuroprotective effects.Conclusions Our study demonstrated that healthy adult plasma treatment protected the structural and functional integrity of blood-brain barrier,reduced neuronal apoptosis and improved functional recovery via FGF21,opening a new avenue for ischaemic stroke therapy.