Investigating the Changes in Air Pollutant Emissions over the Beijing-Tianjin-Hebei Region in February from 2014 to 2019 through an Inverse Emission Method

In recent years,China has implemented several measures to improve air quality.The Beijing-Tianjin-Hebei(BTH)region is one area that has suffered from the most serious air pollution in China and has undergone huge changes in air quality in the past few years.How to scientifically assess these change processes remain the key issue in further improving the air quality over this region in the future.To evaluate the changes in major air pollutant emissions over this region,this paper employs ensemble Kalman filtering(EnKF)for integrating the national ground monitoring pollutant observation data and the Nested Air Quality Prediction Modeling System(NAQPMS)simulation data to inversely estimate the emission rates of SO_(2),NOX,CO,and primary PM_(2.5)over BTH region in February from 2014 to 2019.The results show that SO_(2),NOX,CO,and primary PM_(2.5)emissions in the BTH region decreased in February from 2014 to 2019 by 83%,37%,41%,and 42%,while decreases in Beijing during this period were 86%,67%,59%,and 65%,respectively.Compared with the prior emission inventory,the inversion emission inventory reduces the uncertainty of multi-pollutant simulation in the BTH region,with simulated root mean square errors of the monthly average concentrations of SO_(2),NOX,PM_(2.5),and CO reduced by 41%,30%,31%,and 22%,respectively.The average uncertainties of SO_(2),NOX,PM_(2.5),and CO inversion emissions in2014-19 are±14.03%yr^(-1),±28.91%yr^(-1),±126.15%yr^(-1),and±43.58%yr^(-1).Compared with the uncertainty of MEIC emission,the uncertainties of all species changed by+2%yr^(-1),-2%yr^(-1),-26%yr^(-1),and-4%yr^(-1),respectively.The spatial distribution results illustrate that air pollutant emissions are mainly distributed over the eastern and southern BTH regions.The spatial gap between the inversion emissions and MEIC emissions was further closed in 2019 compared to 2014.The results of this paper can provide a new reference for assessing changes in air pollution emissions over the BTH region in recent years and validating a bottom-up emission inventory.

Impacts of the atmospheric apparent heat source over the Tibetan Plateau on summertime ozone vertical distributions over Lhasa

The Tibetan Plateau(TP)is an area sensitive to climate change,where the ozone distribution affects the atmospheric environment of the TP and its surrounding regions.The relatively low total column ozone over the TP in boreal summer and its spatiotemporal variations have received extensive attention.In this study,five-year balloon-borne measurements of ozone over Lhasa in boreal summer are used to investigate the influences of the apparent heat source(Q1)on the ozone vertical structure over the plateau.The mechanisms for the above processes are also explored.The results show that the tropospheric ozone mixing ratio over Lhasa decreases when the total atmospheric Q1 in the troposphere over the TP is relatively high.Strengthened ascending motions are accompanied by enhanced Q1 over the main TP region.Consequently,the tropospheric ozone mixing ratio over Lhasa decreases when Q1 is higher in summer,which is attributed to the upward transport of the ozone-poor surface air.

Comparative Analysis of Protein Expression Concomitant with DNA Methyltransferase 3A Depletion in a Melanoma Cell Line

DNA methyltransferase 3A (Dnmt3a), a de novo methyltransferase, has attracted a great deal of attention for its important role played in tumorigenesis. We have previously demonstrated that melanoma is unable to grow in-vivo in conditions of Dnmt3a depletion in a mouse model. In this study, we cultured the Dnmt3a depletion B16 melanoma (Dnmt3a-D) cell line to conduct a comparative analysis of protein expression con-comitant with Dnmt3a depletion in a melanoma cell line. After two-dimensional separation, by gel electro-phoresis and liquid chromatography, combined with mass spectrometry analysis (1DE-LC-MS/MS), the re-sults demonstrated that 467 proteins were up-regulated and 535 proteins were down-regulated in the Dnmt3a-D cell line compared to the negative control (NC) cell line. The Genome Ontology (GO) and KEGG pathway were used to further analyze the altered proteins. KEGG pathway analysis indicated that the MAPK signaling pathway exhibited a greater alteration in proteins, an interesting finding due to the close relation-ship with tumorigenesis. The results strongly suggested that Dnmt3a potentially controls the process of tu-morigenesis through the regulation of the proteins (JNK1, p38α, ERK1, ERK2, and BRAF) involved in tu-mor-related pathways, such as the MAPK signaling pathway and melanoma pathway.

首次在北半球平流层西风带探测到汤加火山喷发的气溶胶

2022年初,南太平洋汤加火山喷发向平流层注入大量气溶胶和水汽,影响了全球气候.目前对于火山气溶胶演变过程和作用的认识仍存在很大不确定性,尤其在喷发初期,缺乏火山烟羽中微物理量的原位观测数据.汤加火山喷发12周后,球载探测仪在云南丽江测到火山烟羽,这是在北半球平流层西风带首次实现此类观测.观测数据显示气溶胶数浓度为~1 cm^(-3),粒径集中在0.42~1.27μm,大于背景气溶胶(0.22~0.42μm);在火山烟羽中存在明显的气溶胶与水汽分层现象.这是首次利用原位观测数据给出汤加火山烟羽的微观特征,有助于进一步模拟火山烟羽中的物理化学过程.