Background Postoperative ileus is most common complication after abdominal and pelvicsurgery.Evidences from randomized clinical trials(RCTs)suggest the postoperative coffee consumption shortens the length of ileus and...Background Postoperative ileus is most common complication after abdominal and pelvicsurgery.Evidences from randomized clinical trials(RCTs)suggest the postoperative coffee consumption shortens the length of ileus and length of hospital stay.Objective The purpose of this systematically searched meta-analysis was to assess the effects of postoperative coffee consumption on different bowel parameters and length of hospital stay.We compared the effect of caffeinated and decaffeinated coffee as well as assessed the evidence of complication,safety and efficacy of coffee consumption postoperatively.Design Two researchers independently screened three databases(PubMed,Google Scholar and Web of Science)for potential studies published before October 2017.Summary standardized mean difference(SMD)and 95%confidence interval(CI)were calculated with the random-effects model and fixed-effects model.Publication bias was assessed via Begg’s and Egger’s tests and funnel plot inspection.Results Six studies including 491 patients were identified.A total of 230 patients received coffee with 233 controls.Postoperative coffee consumption decreased time to first bowel movement(SMD-0.63,95%CI-0.99 to-0.26;P=0.003),time to first flatus(SMD-0.76,95%CI-1.14 to-0.38;P=0.002),time to solid food tolerance(SMD-0.63,95%CI-1.06 to-0.19;P=0.014),time to first defecation(SMD-1.32,95%CI-2.39 to-2.24;P=0.002)and length of hospital stay(SMD-1.25,95%CI-2.15 to-0.35;P=0.001).In decaffeinated coffee group,decreased time to first bowel movement and time to first flatus were not statistically significant.The difference in incidence of postoperative complications between coffee and control group was not significant.Conclusions Coffee consumption is safe and might offer a simple approach to reduce ileus following surgery.展开更多
基金supported by Sichuan Provincial Science and Technology Support Project(2016SZ0047)National Natural Science Foundation of China(No.30901427)Chinese Medical Board Grant on Evidence-Based Medicine,New York,USA(No.98-680).
文摘Background Postoperative ileus is most common complication after abdominal and pelvicsurgery.Evidences from randomized clinical trials(RCTs)suggest the postoperative coffee consumption shortens the length of ileus and length of hospital stay.Objective The purpose of this systematically searched meta-analysis was to assess the effects of postoperative coffee consumption on different bowel parameters and length of hospital stay.We compared the effect of caffeinated and decaffeinated coffee as well as assessed the evidence of complication,safety and efficacy of coffee consumption postoperatively.Design Two researchers independently screened three databases(PubMed,Google Scholar and Web of Science)for potential studies published before October 2017.Summary standardized mean difference(SMD)and 95%confidence interval(CI)were calculated with the random-effects model and fixed-effects model.Publication bias was assessed via Begg’s and Egger’s tests and funnel plot inspection.Results Six studies including 491 patients were identified.A total of 230 patients received coffee with 233 controls.Postoperative coffee consumption decreased time to first bowel movement(SMD-0.63,95%CI-0.99 to-0.26;P=0.003),time to first flatus(SMD-0.76,95%CI-1.14 to-0.38;P=0.002),time to solid food tolerance(SMD-0.63,95%CI-1.06 to-0.19;P=0.014),time to first defecation(SMD-1.32,95%CI-2.39 to-2.24;P=0.002)and length of hospital stay(SMD-1.25,95%CI-2.15 to-0.35;P=0.001).In decaffeinated coffee group,decreased time to first bowel movement and time to first flatus were not statistically significant.The difference in incidence of postoperative complications between coffee and control group was not significant.Conclusions Coffee consumption is safe and might offer a simple approach to reduce ileus following surgery.
