Electrochemical oxidation of hydroquinone（1a） has been studied in the presence of 6-methyl-2-thiouracil（3a） and 6-propyl-2-thiouracil（3b） as nucleophiles in a DMF/buffer mixture,using cyclic voltammetry and cont...Electrochemical oxidation of hydroquinone（1a） has been studied in the presence of 6-methyl-2-thiouracil（3a） and 6-propyl-2-thiouracil（3b） as nucleophiles in a DMF/buffer mixture,using cyclic voltammetry and controlled-potential coulometry.The results indicated that the p-quinone（2a） derived from 1a participates in a 1 4-Michael addition reaction with the thiouracil derivatives（3a–b） to form the corresponding hydroquinonethioether derivatives（6a–6b）.The electrosynthesis of these compounds（6a–b） has been successfully performed on carbon rod electrodes in an undivided cell in good yield and purity.展开更多
基金Semnan University Research Council for financial supports of this work
文摘Electrochemical oxidation of hydroquinone（1a） has been studied in the presence of 6-methyl-2-thiouracil（3a） and 6-propyl-2-thiouracil（3b） as nucleophiles in a DMF/buffer mixture,using cyclic voltammetry and controlled-potential coulometry.The results indicated that the p-quinone（2a） derived from 1a participates in a 1 4-Michael addition reaction with the thiouracil derivatives（3a–b） to form the corresponding hydroquinonethioether derivatives（6a–6b）.The electrosynthesis of these compounds（6a–b） has been successfully performed on carbon rod electrodes in an undivided cell in good yield and purity.
