The beneficial effects of feeding syrup of peaches and pears (peel and pulp) & green tea on the restoration of the changes produced by feeding high sucrose diet on plasma lipid profile, plasma antioxidant activity...The beneficial effects of feeding syrup of peaches and pears (peel and pulp) & green tea on the restoration of the changes produced by feeding high sucrose diet on plasma lipid profile, plasma antioxidant activity, and antioxidant enzymes in red blood cells (RBC) hemolysate were studied. High sucrose diet induced hyperlipidemia as manifested by significant (P ≤ 0.05) increases in the levels of cholesterol, triglycerides (TG) and low density lipoproteins (LDL) in plasma from 103.33 ± 1.8, 61.17 ± 0.48 and 26.6 ± 5.01 mg/dl to 136.67 ± 2.2, 81.3 ± 1.5 and 64.6 ± 6.5 mg/dl respectively. The high density lipoproteins (HDL) level was not significantly affected. TG levels in heart muscles increased significantly P ≤ 0.05 from the level of 194.14 ± 4.35 μg/g in the negative control to 269.72 ± 5.39 μg/g. Administration of fruits syrup and green tea resulted in a significant variable reduction in the elevated levels of cholesterol, TG and LDL and TG in the heart. Administration of sucrose resulted also in elevation of Malondialdehyde (MDA) in plasma from 5.06 ± 0.18 in the negative control to 14.81 ± 0.48 μmol/L in the positive control. This was also accompanied by reduction in the activities of supper oxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT) and a decrease in the concentration of reduced glutathione (GSH) in plasma, indicating lipid peroxidation. The activities of SOD, GSH-Px, CAT in the negative control were 8.96 ± 0.19, 315.67 ± 5.86, 209 ± 2.18 U/gHb respectively and were reduced significantly in the positive control to 4.7 ± 0.2, 273.83 ± 7.85, 207 ± 2.53 U/g Hb. There was a significant decrease in the level of total antioxidant status (TAS) in plasma from 1.45 ± 0.09 to 0.88 ± 0.09 nmol/L. However, no statistically significant changes were noticed in the concentrations of plasma total proteins and albumin. Intake of syrup of peaches and pears (peel and pulp) & green tea increased the level of TAS and GSH and decreased the level of LDL. The treatment also decreased significantly (P ≤ 0.05) the levels of plasma cholesterol, TG and heart TG levels. The activities of SOD and GSH-Px were increased following the treatment. It can be concluded that syrup of peaches and pears (peel and pulp) & green tea modulate lipid metabolism and enhance antioxidant status and in this respect green tea produced the best effect followed by peels of pears and peaches. The beneficial effect produced by fruits syrup and green tea may be due to their contents of phytochemicals.展开更多
In the present investigation, the valorization of sweet potato (Ipomoea batatas L.) wastes into food application with health benefits was studied. Growing interest in the replacement of synthetic food antioxidants by ...In the present investigation, the valorization of sweet potato (Ipomoea batatas L.) wastes into food application with health benefits was studied. Growing interest in the replacement of synthetic food antioxidants by natural ones has fostered research on vegetable sources and screening of raw materials to identify new antioxidants. Different parts of sweet potato contain various phenolic activities. The sweet potato peel had the highest antioxidant activity as compared to other parts. It was reported that sweet potato contains bioactive compounds such as Flavonoids, Polyphenols, The present study was executed to examine the antioxidant components of sweet potato peel and their addition to fermented cow’s milk to improve lipid profile in rats fed high fat diet. Fermented milk was prepared from cow’s milk fortified with 1% and 2% of sweet potato peels (SPP), before inoculation with starter culture containing (S. thermophilus TH4, L. acidophilus La5 and L. bulgaricus). It was found that addition of SPP had no significant effects on the sensory attributes (appearance, body, texture, and flavor) as compared to the control samples. Increasing the percentage of SPP resulted in a decrease in the viscosity of the fermented milk. When SPP powder was included in the diet and fed to rats, there was a significant decrease in the activities of serum transaminases (ALT and AST). Results also showed that the fermented milk administration to hyperlipidemic/hyper-cholesterolemic rats induced a significant decrease in the total cholesterol, LDL, protein and triglycerides, and a significant increase in HDL concentration. Histopathological examination showed that groups fed with SPP blended fermented milk showed less pathological changes compared to the positive control group. The main results indicated that there is a high potential for sweet potato peel extract to be utilized as antioxidant in food systems due to its high phenolic contents. It can be concluded that the antioxidant components in purple sweet potato peel when administered with fermented cow’s milk can improve serum lipid status in rats fed high fat diet.展开更多
文摘The beneficial effects of feeding syrup of peaches and pears (peel and pulp) & green tea on the restoration of the changes produced by feeding high sucrose diet on plasma lipid profile, plasma antioxidant activity, and antioxidant enzymes in red blood cells (RBC) hemolysate were studied. High sucrose diet induced hyperlipidemia as manifested by significant (P ≤ 0.05) increases in the levels of cholesterol, triglycerides (TG) and low density lipoproteins (LDL) in plasma from 103.33 ± 1.8, 61.17 ± 0.48 and 26.6 ± 5.01 mg/dl to 136.67 ± 2.2, 81.3 ± 1.5 and 64.6 ± 6.5 mg/dl respectively. The high density lipoproteins (HDL) level was not significantly affected. TG levels in heart muscles increased significantly P ≤ 0.05 from the level of 194.14 ± 4.35 μg/g in the negative control to 269.72 ± 5.39 μg/g. Administration of fruits syrup and green tea resulted in a significant variable reduction in the elevated levels of cholesterol, TG and LDL and TG in the heart. Administration of sucrose resulted also in elevation of Malondialdehyde (MDA) in plasma from 5.06 ± 0.18 in the negative control to 14.81 ± 0.48 μmol/L in the positive control. This was also accompanied by reduction in the activities of supper oxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT) and a decrease in the concentration of reduced glutathione (GSH) in plasma, indicating lipid peroxidation. The activities of SOD, GSH-Px, CAT in the negative control were 8.96 ± 0.19, 315.67 ± 5.86, 209 ± 2.18 U/gHb respectively and were reduced significantly in the positive control to 4.7 ± 0.2, 273.83 ± 7.85, 207 ± 2.53 U/g Hb. There was a significant decrease in the level of total antioxidant status (TAS) in plasma from 1.45 ± 0.09 to 0.88 ± 0.09 nmol/L. However, no statistically significant changes were noticed in the concentrations of plasma total proteins and albumin. Intake of syrup of peaches and pears (peel and pulp) & green tea increased the level of TAS and GSH and decreased the level of LDL. The treatment also decreased significantly (P ≤ 0.05) the levels of plasma cholesterol, TG and heart TG levels. The activities of SOD and GSH-Px were increased following the treatment. It can be concluded that syrup of peaches and pears (peel and pulp) & green tea modulate lipid metabolism and enhance antioxidant status and in this respect green tea produced the best effect followed by peels of pears and peaches. The beneficial effect produced by fruits syrup and green tea may be due to their contents of phytochemicals.
文摘In the present investigation, the valorization of sweet potato (Ipomoea batatas L.) wastes into food application with health benefits was studied. Growing interest in the replacement of synthetic food antioxidants by natural ones has fostered research on vegetable sources and screening of raw materials to identify new antioxidants. Different parts of sweet potato contain various phenolic activities. The sweet potato peel had the highest antioxidant activity as compared to other parts. It was reported that sweet potato contains bioactive compounds such as Flavonoids, Polyphenols, The present study was executed to examine the antioxidant components of sweet potato peel and their addition to fermented cow’s milk to improve lipid profile in rats fed high fat diet. Fermented milk was prepared from cow’s milk fortified with 1% and 2% of sweet potato peels (SPP), before inoculation with starter culture containing (S. thermophilus TH4, L. acidophilus La5 and L. bulgaricus). It was found that addition of SPP had no significant effects on the sensory attributes (appearance, body, texture, and flavor) as compared to the control samples. Increasing the percentage of SPP resulted in a decrease in the viscosity of the fermented milk. When SPP powder was included in the diet and fed to rats, there was a significant decrease in the activities of serum transaminases (ALT and AST). Results also showed that the fermented milk administration to hyperlipidemic/hyper-cholesterolemic rats induced a significant decrease in the total cholesterol, LDL, protein and triglycerides, and a significant increase in HDL concentration. Histopathological examination showed that groups fed with SPP blended fermented milk showed less pathological changes compared to the positive control group. The main results indicated that there is a high potential for sweet potato peel extract to be utilized as antioxidant in food systems due to its high phenolic contents. It can be concluded that the antioxidant components in purple sweet potato peel when administered with fermented cow’s milk can improve serum lipid status in rats fed high fat diet.