Management of non-ST-segment elevation myocardial in-farction in patients aged≥80 years:a meta-analysis of ran-domized controlled trials

Coronary artery disease(CAD)is the major cause of morbidity and mortality in elderly patients.^([1])Despite this,elderly patients are under-represented in most trials of CAD.Non-ST-segment elevation myocardial infarction(NSTEMI)is a common cause of hospitalization among patients≥80 years of age,^([2])and with an aging global population,there is a pressing need to establish the optimal management strategy for these patients.Therefore,we conducted a meta-analysis of all randomized control trials(RCTs)performed to date in patients≥80 years of age,comparing an initial invasive versus conservative strategy to provide insights into their optimal initial management strategy.