The relationship between acceptance of illness and quality of life among men who have sex with men living with human immunodeficiency virus:A cross-sectional study

Objectives To explore the relationship between acceptance of illness and quality of life(QOL),and factors associated with acceptance of illness among men who have sex with men(MSM)living with human immunodeficiency virus(HIV).Methods Three hundred and one MSM were recruited from an HIV clinic between August and December 2018.The battery of measurements consisted of the Acceptance of Illness Scale,World Health Organization Quality of Life Questionnaire for HIV brief version,HIV Cognitive Appraisal Scale and a self-designed questionnaire used to collect general information.Pearson correlation test was used to examine the relationship between acceptance of illness and QOL.Univariate and multivariate ordinal logistic regression analyses were used to examine whether the general data(demographic and HIV-related clinical data)and HIV cognitive appraisal were associated with acceptance of illness levels.Results Descriptive analysis showed the acceptance level among MSM living with HIV was moderate(Mean=26.29,SD=5.28).Those with a better acceptance of illness had a better QOL(r=0.69,P<0.01).In the multivariate ordinal logistic regression model,education level,threat appraisals(OR:1.09;95%CI[1.06–1.13]),and controllability appraisals(OR:0.82;95%CI[0.71–0.94])were significantly associated with acceptance of illness.Conclusions Results showed acceptance level was moderate and had a positive correlation with QOL.High level of education,low threat appraisals and high controllability appraisals were related to high illness acceptance.This finding highlights the importance of focusing on HIV-infected MSM with low education and on their perceptions of threat and controllability about HIV-related issues when designing interventions to promote illness acceptance in this vulnerable population.

二维裂隙密度及其渗透率的逾渗关系研究

在低渗透介质储存中,裂隙是石油运移的主要通道。因而裂隙介质的渗透率是石油勘探的一个重要参数。应用连续逾渗模型分析,把低渗透储存的裂隙网络合理简化,能够对深层复杂介质的渗透规律进行研究。使用排除体积对裂隙密度进行无量纲化,从而使裂隙的宏观性与裂隙的形状无关。使用Monte Carlo方法模拟得到不同裂隙密度时的裂隙网络图,然后基于连续逾渗模型,采用有限元方法利用COMSOL Multiphysics求解器解,数值模拟得到裂隙的渗透率与无量纲化密度成乘幂关系。该模拟结果可能为裂隙网络渗透率的定量评价提供一个简单而又实用的方法。这一规则的发现也增强了逾渗理论在油气田勘探中的应用。

邻炔基苯胺的电化学环化合成3-碘吲哚

吲哚及其衍生物是一类重要的杂环化合物,也是多种天然产物和合成药物的骨架分子.3-碘吲哚在其选择性功能化中充当着重要的中间体.电化学氧化廉价易得的碘盐,促使邻炔基苯胺分子内环化,便捷地合成了一系列3-碘吲哚类化合物,目标化合物可获得良好至优秀的产率.该方法条件温和,官能团适用范围广,无需额外添加氧化剂和碱,是一条操作简便、绿色可持续地合成3-碘吲哚类化合物的途径.

The deep thermal structure of the lithosphere in the northwestern South China Sea and its control on the shallow tectonics

The northwestern sub-basin of South China Sea(SCS)is a unique tectonic unit formed in the early spreading of the SCS.The northwestern Sub-basin has a series of complex geological structures such as seamounts and fault zones surrounded by the Xisha Trough,the Zhongsha Massif,and the Pearl River Valley.These extensional structures and magmatic activity in the northwestern sub-basin are closely related to the lithospheric structure and its deformation.However,details of the deep lithosphere structure are still poorly known.Here,we obtained detailed data of water and Moho depth using sonar buoys,Extended Spread Profiles(ESP),Ocean Bottom Seismometer(OBS),both Multi-beam and land-sea joint seismic surveys in the northwestern sub-basin and its surrounding areas.Then we adopted a thermal isostasy method to calculate the depth of the Lithosphere-Asthenosphere Boundary(LAB)in the northwestern sub-basin of the SCS and its surrounding regions.Results show that the range of LAB depth is~25–110 km.The shallowest burial depth is 25–60 km occurring in the ocean basin.The depth increases to 60–110 km toward the continental margin.The lithospheric structure on the north and south sides of the Xisha Trough is symmetrical and shows the deep structure and thermal features of aborted rifts.The LAB depth in the Zhongsha Trough and the Zhongsha Massif increased from 60 to 70 km southwestwards,consistent with the trend of surface morphology.The LAB depth to the west side of the Pearl River Valley is 60–80 km,and the thinning of the lithosphere is related to the distribution of faults,depressions and the magmatic activity.The LAB depth in the northwestern sub-basin and the eastern subbasin is less than 60 km with the thinnest part being less than 46 km.Combining ocean drilling,seismic investigation,and seafloor topography,we show that the ocean basin of the northwestern sub-basin of the SCS locates within the 46 km isobath of the LAB.The formation of the rifted valleys and discrete blocks surrounding the ocean basins is both controlled by the regional tectonic movement and the deep thermal state,where their lithospheric structures show strong heterogeneity.