It is estimated that in 2010, 1 in every 250 adults will be a childhood cancer survivor. Today, oncological surgery, radiotherapy and chemotherapy achieve relatively high rates of remission and long-term survival, yet...It is estimated that in 2010, 1 in every 250 adults will be a childhood cancer survivor. Today, oncological surgery, radiotherapy and chemotherapy achieve relatively high rates of remission and long-term survival, yet are often detrimental to fertility. Quality of life is increasingly important to long-term survivors of cancer, and one of the major quality-of-life issues is the ability to produce and raise normal children. Developments in the near future in the emerging field of fertility preservation in cancer survivors promise to be very exciting. This article reviews the published literature, discusses the effects of cancer treatment on fertility and presents the options available today thanks to advances in assisted-reproduction technology for maintaining fertility in male and female patients undergoing this type of treatment. The various diagnostic methods of assessing the fertility potential and the efficacy of in vitro fertilization （IVF） after cancer treatment are also presented.展开更多
The changes in operative gynecology in the past decades have been dramatic in terms of shifting strategies.For example there has been a shift not only from ultraradical techniques such as exenterations,which were firs...The changes in operative gynecology in the past decades have been dramatic in terms of shifting strategies.For example there has been a shift not only from ultraradical techniques such as exenterations,which were first proposed by Brunschwig in 19481 and used in gynecologic oncology by Felix Rutledge in 1974,2 to minimally invasive techniques such as endoscopic or robotic surgery,but also the level of training in terms of anatomical and surgical skills,which are significantly influenced by medico-legal aspects(i.e.,legal regulations).Thus there has been a significant reduction of personal expertise and a changing attitude towards life goals.Moreover,with the European Working Time Directive leading to a reduction in working hours and expansion of the number of trainees,surgical training in areas such as operative experience,patient management,communication,and teaching skills has been getting worse.展开更多
文摘It is estimated that in 2010, 1 in every 250 adults will be a childhood cancer survivor. Today, oncological surgery, radiotherapy and chemotherapy achieve relatively high rates of remission and long-term survival, yet are often detrimental to fertility. Quality of life is increasingly important to long-term survivors of cancer, and one of the major quality-of-life issues is the ability to produce and raise normal children. Developments in the near future in the emerging field of fertility preservation in cancer survivors promise to be very exciting. This article reviews the published literature, discusses the effects of cancer treatment on fertility and presents the options available today thanks to advances in assisted-reproduction technology for maintaining fertility in male and female patients undergoing this type of treatment. The various diagnostic methods of assessing the fertility potential and the efficacy of in vitro fertilization （IVF） after cancer treatment are also presented.
文摘The changes in operative gynecology in the past decades have been dramatic in terms of shifting strategies.For example there has been a shift not only from ultraradical techniques such as exenterations,which were first proposed by Brunschwig in 19481 and used in gynecologic oncology by Felix Rutledge in 1974,2 to minimally invasive techniques such as endoscopic or robotic surgery,but also the level of training in terms of anatomical and surgical skills,which are significantly influenced by medico-legal aspects(i.e.,legal regulations).Thus there has been a significant reduction of personal expertise and a changing attitude towards life goals.Moreover,with the European Working Time Directive leading to a reduction in working hours and expansion of the number of trainees,surgical training in areas such as operative experience,patient management,communication,and teaching skills has been getting worse.
