2-Methoxyjuglone,a member of the 1,4-naphthoquinone family,was first obtained through semi-synthesis based on 2-hydroxyjuglone as the precursor in 1966.It has been isolated and identified from different plant species ...2-Methoxyjuglone,a member of the 1,4-naphthoquinone family,was first obtained through semi-synthesis based on 2-hydroxyjuglone as the precursor in 1966.It has been isolated and identified from different plant species of the Juglandaceae,Sterculiaceae,and Proteaceae families.2-Methoxyjuglone has been demonstrated to possess a wide range of biological activities,including antitumor,antifungal,and antibacterial activities;in addition,it has been shown to poison fish and inhibit seed germination.These properties make 2-methoxyjuglone a promising bioactive compound for pharmaceutical and agricultural purposes.This review article provides an overview of the current research progress on 2-methoxyjuglone for the first time,with a primary focus on the plant sources,extraction,identification,synthesis,and biological activities associated with this compound for further development.展开更多
A new diarylheptanoid glucoside,（8R,9R）-17-methoxy-2-oxatricyclo[13.2.2.1^（3.7）]icosa-l（17）,3（20）,4,6, 15,18-hexaene-4,9,10-triol-9-O-β-D-glucopyranoside（1）,namely jugcathayenoside,together with two known d...A new diarylheptanoid glucoside,（8R,9R）-17-methoxy-2-oxatricyclo[13.2.2.1^（3.7）]icosa-l（17）,3（20）,4,6, 15,18-hexaene-4,9,10-triol-9-O-β-D-glucopyranoside（1）,namely jugcathayenoside,together with two known diarylheptanoids,（＋）-galeon（2） and 4-hydroxy-17-methoxy-2-oxatricyclo[13.2.2.1^（3,7） ]icosa-1（17）,3（20）,4,6,15,18-hexaene-9-one（3）,were isolated from the root bark of Juglans cathayensis. Their structures were elucidated on the basis of extensive spectroscopic data analysis.展开更多
基金supported by the National Natural Science Foundation of China(No.21572073 and No.3150010539).
文摘2-Methoxyjuglone,a member of the 1,4-naphthoquinone family,was first obtained through semi-synthesis based on 2-hydroxyjuglone as the precursor in 1966.It has been isolated and identified from different plant species of the Juglandaceae,Sterculiaceae,and Proteaceae families.2-Methoxyjuglone has been demonstrated to possess a wide range of biological activities,including antitumor,antifungal,and antibacterial activities;in addition,it has been shown to poison fish and inhibit seed germination.These properties make 2-methoxyjuglone a promising bioactive compound for pharmaceutical and agricultural purposes.This review article provides an overview of the current research progress on 2-methoxyjuglone for the first time,with a primary focus on the plant sources,extraction,identification,synthesis,and biological activities associated with this compound for further development.
基金Financial support from the Natural Science Foundation of China (Nos.30873361,81072547 and 31270394)Wuhan Program for Science and Technology(No.2013060501010158)the Ministry of Science and Technology of the People's Republic of China (International Cooperative Project,No.2010DFA32430)
文摘A new diarylheptanoid glucoside,（8R,9R）-17-methoxy-2-oxatricyclo[13.2.2.1^（3.7）]icosa-l（17）,3（20）,4,6, 15,18-hexaene-4,9,10-triol-9-O-β-D-glucopyranoside（1）,namely jugcathayenoside,together with two known diarylheptanoids,（＋）-galeon（2） and 4-hydroxy-17-methoxy-2-oxatricyclo[13.2.2.1^（3,7） ]icosa-1（17）,3（20）,4,6,15,18-hexaene-9-one（3）,were isolated from the root bark of Juglans cathayensis. Their structures were elucidated on the basis of extensive spectroscopic data analysis.
