The diagnostic yield of capsule endoscopy depends on the quality of visualization of the small-bowel wall and complete passage through the small bowel. This study examined the effect of bowel preparation on the volume...The diagnostic yield of capsule endoscopy depends on the quality of visualization of the small-bowel wall and complete passage through the small bowel. This study examined the effect of bowel preparation on the volume of intestinal content and on small-bowel transit. Sixty-one consecutive patients (34 men, 27 women; mean age 56 years, range 17-88 years)were enrolled in the study. Although not randomized, 33 patients received a bowel preparation, and 28 had no preparation. Gastric emptying, small-bowel transit time, overall preparation assessment, and bowel-wall visualization were evaluated by 3 investigators who were unaware of whether the patient had undergone bowel preparation. Small-bowel transit time was significantly shorter in patients with bowel preparation (median 213 minutes: 95%CI[190, 267]) than in those without preparation (median 253 minutes: 95%CI[228, 307]) (p < 0.01). The capsule reached the cecum in 97%of patients in the bowel-preparation group, compared with 76%in the nonpreparation group (p = 0.02). Bowel preparation improved the quality of visualization significantly; this effect was more pronounced in the distal small bowel. This study demonstrated that bowel preparation accelerates small-bowel capsule transit and leads to a higher rate of complete capsule endoscopy. Visualization of the small bowel was improved by bowel preparation. Bowel preparation before capsule endoscopy is recommended.展开更多
文摘The diagnostic yield of capsule endoscopy depends on the quality of visualization of the small-bowel wall and complete passage through the small bowel. This study examined the effect of bowel preparation on the volume of intestinal content and on small-bowel transit. Sixty-one consecutive patients (34 men, 27 women; mean age 56 years, range 17-88 years)were enrolled in the study. Although not randomized, 33 patients received a bowel preparation, and 28 had no preparation. Gastric emptying, small-bowel transit time, overall preparation assessment, and bowel-wall visualization were evaluated by 3 investigators who were unaware of whether the patient had undergone bowel preparation. Small-bowel transit time was significantly shorter in patients with bowel preparation (median 213 minutes: 95%CI[190, 267]) than in those without preparation (median 253 minutes: 95%CI[228, 307]) (p < 0.01). The capsule reached the cecum in 97%of patients in the bowel-preparation group, compared with 76%in the nonpreparation group (p = 0.02). Bowel preparation improved the quality of visualization significantly; this effect was more pronounced in the distal small bowel. This study demonstrated that bowel preparation accelerates small-bowel capsule transit and leads to a higher rate of complete capsule endoscopy. Visualization of the small bowel was improved by bowel preparation. Bowel preparation before capsule endoscopy is recommended.
