The cochlear implant is a prosthesis that is capable to replace listening capability among patients with sensorineural hearing loss. Many studies suggest a negative relationship among duration of sound deprivation and...The cochlear implant is a prosthesis that is capable to replace listening capability among patients with sensorineural hearing loss. Many studies suggest a negative relationship among duration of sound deprivation and audiometric gain (by means of speech perception test) after cochlear implantation. We evaluated surgical and audiologic results among post-lingual deafened adults, in different times of sound deprivation, and correlated with social isolation, presence of vertigo or tinnitus, and the speech therapy yield, between pre- and post-operative stages. A retrospective study was conducted on patients with post-lingual hearing loss, aged over 18 years old who underwent cochlear implant surgery in a public hospital from 2004 to 2014. Audiological, socio-demographic questionnaire, and manifestations of vertigo and tinnitus, during pre- and post-operative stages, were compared and correlating to the different periods of sound deprivation. Two groups were studied. The group A was composed of 38 participants (14 male and 24 female) with sound deprivation of less than 10 years;and group B was composed of 17 participants (8 male and 9 female) with sound deprivation longer than 10 years. We found no differences regarding age, sex, duration of sound deprivation, mean pure-tone audiometric results (pre- and post-surgery), and speech perception tests (pre-operatively). After one year of the surgery, we observed a significant difference between both groups, with a better performance to group A. The results of speech perception test, after cochlear implantation in group B, were worse than the results obtained in group A, although these correlations are not determinant whether to perform cochlear implant surgery or not.展开更多
Age-related hearing loss is the most common cause of adult auditory dysfunction. It is characterized by bilateral, progressive auditory deterioration associated with the aging process. There currently are limited opti...Age-related hearing loss is the most common cause of adult auditory dysfunction. It is characterized by bilateral, progressive auditory deterioration associated with the aging process. There currently are limited options for the treatment as hearing aids or cochlear implants. To establish novel strategies for the treatment of this entity, it is crucial to elucidate the mechanisms of age-related hearing loss. Its etiology is believed to be multifactorial including both intrinsic and extrinsic factors. Oxidative damage, as seen in other aging organs systems, may play an essential role in the pathogenesis of the age-related hearing loss. Studies on animal models and human temporal bones have indicated a close relationship between degeneration of the cochlear lateral wall and hearing loss. Additional therapies that may prove beneficial in the treatment of age-related hearing loss include stem cell therapy, which we intend to review in this manuscript.展开更多
Introduction: Cochlear implant (CI) surgery allows hearing reestablishment among individuals with severe to profound hearing loss. However, only few patients will need a surgical reassessment. Objectives: To verify th...Introduction: Cochlear implant (CI) surgery allows hearing reestablishment among individuals with severe to profound hearing loss. However, only few patients will need a surgical reassessment. Objectives: To verify the incidence of surgical reassessment among adult patients;to verify the reasons that led the second surgery to be performed;to verify the efficacy—and audiological outcomes—of revisional surgery. Method: A longitudinal retrospective cohort study was carried out with the review of medical records, of adult patients, with bilateral severe to profound sensorineural hearing loss who underwent to revisional surgery, from 2004 to 2016 at a CI Center, in Brazil. Results: One hundred fifty-eight CI surgeries were performed among 137 adult patients. Fourteen revisional surgeries were performed among 10 patients: five surgeries were due by displacement of the internal unit;one because of having excessive subcutaneous tissue;one due to non-progression of the electrodes during the initial surgery, one late tympanic membrane perforation, one late facial palsy and, one due to a suture dehiscence in the surgical incision with exposure of the internal unit. Conclusions: The incidence of surgical reassessment among adult CI patients was 8.9%. All implanted patients that underwent a new surgical approach maintained an improved auditory threshold after revisional CI surgery.展开更多
文摘The cochlear implant is a prosthesis that is capable to replace listening capability among patients with sensorineural hearing loss. Many studies suggest a negative relationship among duration of sound deprivation and audiometric gain (by means of speech perception test) after cochlear implantation. We evaluated surgical and audiologic results among post-lingual deafened adults, in different times of sound deprivation, and correlated with social isolation, presence of vertigo or tinnitus, and the speech therapy yield, between pre- and post-operative stages. A retrospective study was conducted on patients with post-lingual hearing loss, aged over 18 years old who underwent cochlear implant surgery in a public hospital from 2004 to 2014. Audiological, socio-demographic questionnaire, and manifestations of vertigo and tinnitus, during pre- and post-operative stages, were compared and correlating to the different periods of sound deprivation. Two groups were studied. The group A was composed of 38 participants (14 male and 24 female) with sound deprivation of less than 10 years;and group B was composed of 17 participants (8 male and 9 female) with sound deprivation longer than 10 years. We found no differences regarding age, sex, duration of sound deprivation, mean pure-tone audiometric results (pre- and post-surgery), and speech perception tests (pre-operatively). After one year of the surgery, we observed a significant difference between both groups, with a better performance to group A. The results of speech perception test, after cochlear implantation in group B, were worse than the results obtained in group A, although these correlations are not determinant whether to perform cochlear implant surgery or not.
文摘Age-related hearing loss is the most common cause of adult auditory dysfunction. It is characterized by bilateral, progressive auditory deterioration associated with the aging process. There currently are limited options for the treatment as hearing aids or cochlear implants. To establish novel strategies for the treatment of this entity, it is crucial to elucidate the mechanisms of age-related hearing loss. Its etiology is believed to be multifactorial including both intrinsic and extrinsic factors. Oxidative damage, as seen in other aging organs systems, may play an essential role in the pathogenesis of the age-related hearing loss. Studies on animal models and human temporal bones have indicated a close relationship between degeneration of the cochlear lateral wall and hearing loss. Additional therapies that may prove beneficial in the treatment of age-related hearing loss include stem cell therapy, which we intend to review in this manuscript.
文摘Introduction: Cochlear implant (CI) surgery allows hearing reestablishment among individuals with severe to profound hearing loss. However, only few patients will need a surgical reassessment. Objectives: To verify the incidence of surgical reassessment among adult patients;to verify the reasons that led the second surgery to be performed;to verify the efficacy—and audiological outcomes—of revisional surgery. Method: A longitudinal retrospective cohort study was carried out with the review of medical records, of adult patients, with bilateral severe to profound sensorineural hearing loss who underwent to revisional surgery, from 2004 to 2016 at a CI Center, in Brazil. Results: One hundred fifty-eight CI surgeries were performed among 137 adult patients. Fourteen revisional surgeries were performed among 10 patients: five surgeries were due by displacement of the internal unit;one because of having excessive subcutaneous tissue;one due to non-progression of the electrodes during the initial surgery, one late tympanic membrane perforation, one late facial palsy and, one due to a suture dehiscence in the surgical incision with exposure of the internal unit. Conclusions: The incidence of surgical reassessment among adult CI patients was 8.9%. All implanted patients that underwent a new surgical approach maintained an improved auditory threshold after revisional CI surgery.
