Introduction: The use of oxytocic plants (OPs) to facilitate childbirth is old and it is a common practice in the world, particularly in northern Benin. Objective: To study the effect of oxytocic plants on the progres...Introduction: The use of oxytocic plants (OPs) to facilitate childbirth is old and it is a common practice in the world, particularly in northern Benin. Objective: To study the effect of oxytocic plants on the progress of labour. Materials and Method: This was a cross-sectional and analytical study with prospective data collection conducted in the public maternity hospitals of Parakou from 15 July 2022 to 15 August 2022. All the parturients admitted to the maternity units were included. Data were entered and processed using Epi Data 3.1fr, Epi info 7.1.3.3 and Excel 2010. The difference was statistically significant for a p-value of less than 0.05. Results: Of 297 parturients surveyed, 109 had used OPs, representing a frequency of use of 36.7%. The average age was 27.5 ± 8.9 years, with extremes of 17 and 45 years. They were in common-law unions (54.1%), housewives (32.1%), from Muslim religion (53.2%), from Bariba ethnic group and related (30.3%) and from a rural area (60.5%). These parturients were pauciparous (37.6%) and primiparous (44.9%). Six OPs were used by the parturients. These were Hybanthus enneaspermus (40.7%), Schrankia leptocarpa (12.0%), Ceratotheca sesamoides (35.2%), Cassytha filiformis (5.6%), Selaginella lepidophylla (5.6%) and Newbouldia leavis (18.5%). The parturients used the leaves (90.6%) and decoction (97.2%). The administration was oral (99.0%) without precise dosage (85.3%) in the third trimester of pregnancy (84.41%) and facilitated delivery (99.1%). Fon and related ethnic groups (p = 0.014), Yoruba and related ethnic groups (p = 0.031), rural background (p = 0.032) and multiparity (p = 0.04) were the factors associated with OPs use. These parturients had a higher risk of caesarean delivery (p = 0.001;OR = 1.8 [1.23 - 2.65]), dynamic dystocia (p = 0.001;OR = 1.3 [1.12 - 1.49]), burnout syndrome (p = 0.002;OR = 1.1 [1.02 - 1.17]), uterine rupture (p = 0.032;OR = 1.1 [0.97 - 1.17]), rapid labour (p = 0.001;OR = 1.6 [1.38 - 2.00]), and risk of postpartum haemorrhage (p = 0.002;OR = 1.15 [1.05 - 1.27]). In contrast, parturients’ use of OPs was found to reduce the risk of their newborns being transferred to neonatology (p = 0.002;OR = 0.50 [0.31 - 0.79]) and dying at birth (p = 0.021;OR = 0.19 [0.03 - 0.94]). Conclusion: The use of OPs is widespread in Parakou. Several factors were associated with it. This use had a protective effect on newborns. This study shows the need to determine the active ingredients of these OPs and emphasise a safer use of them.展开更多
Introduction: The bacteriology-virology laboratory of the teaching university hospital of Brazzaville, was equipped with a real-time PCR device like Miniopticon (Biorad? , France). The aim of this work was to do an ev...Introduction: The bacteriology-virology laboratory of the teaching university hospital of Brazzaville, was equipped with a real-time PCR device like Miniopticon (Biorad? , France). The aim of this work was to do an evaluation of the HIV viral load activity, with a view to proposing some recommendations. Material and methods: Retrospective study, January 2013 to March 2015, in patients on first line ARV three-therapy, pre-inclusion therapy checkup in HIV positive patients, but again screening after sexual abuse in women or accident of exposure (AES). A blood sample on EDTA tube was made and RNA extraction with Qiagen kit. Ultrasensitive HIV-RNA quantification was performed using the Generic HIV real-time PCR assay (Biocentric?, Bandol, France). Results: 126 patients were included. The mean age was 37.63 years +/- 10.43 years, sex ratio F/H = 2.3. The HIV viral load was detectable in 94 cases (74.6%). Concerning patients with detectable viral load (copies/ml): 403 to 996 in 35 cases (37.23%), 1411 to 1812 in 41 cases (43.62%) and >1814 in 5 cases (5.32%) (therapeutic failure). Conclusion: This work reports success in the setting up of the molecular biology unit. Procedures that implement information and education actions on the risks associated with AES must be disclosed.展开更多
文摘Introduction: The use of oxytocic plants (OPs) to facilitate childbirth is old and it is a common practice in the world, particularly in northern Benin. Objective: To study the effect of oxytocic plants on the progress of labour. Materials and Method: This was a cross-sectional and analytical study with prospective data collection conducted in the public maternity hospitals of Parakou from 15 July 2022 to 15 August 2022. All the parturients admitted to the maternity units were included. Data were entered and processed using Epi Data 3.1fr, Epi info 7.1.3.3 and Excel 2010. The difference was statistically significant for a p-value of less than 0.05. Results: Of 297 parturients surveyed, 109 had used OPs, representing a frequency of use of 36.7%. The average age was 27.5 ± 8.9 years, with extremes of 17 and 45 years. They were in common-law unions (54.1%), housewives (32.1%), from Muslim religion (53.2%), from Bariba ethnic group and related (30.3%) and from a rural area (60.5%). These parturients were pauciparous (37.6%) and primiparous (44.9%). Six OPs were used by the parturients. These were Hybanthus enneaspermus (40.7%), Schrankia leptocarpa (12.0%), Ceratotheca sesamoides (35.2%), Cassytha filiformis (5.6%), Selaginella lepidophylla (5.6%) and Newbouldia leavis (18.5%). The parturients used the leaves (90.6%) and decoction (97.2%). The administration was oral (99.0%) without precise dosage (85.3%) in the third trimester of pregnancy (84.41%) and facilitated delivery (99.1%). Fon and related ethnic groups (p = 0.014), Yoruba and related ethnic groups (p = 0.031), rural background (p = 0.032) and multiparity (p = 0.04) were the factors associated with OPs use. These parturients had a higher risk of caesarean delivery (p = 0.001;OR = 1.8 [1.23 - 2.65]), dynamic dystocia (p = 0.001;OR = 1.3 [1.12 - 1.49]), burnout syndrome (p = 0.002;OR = 1.1 [1.02 - 1.17]), uterine rupture (p = 0.032;OR = 1.1 [0.97 - 1.17]), rapid labour (p = 0.001;OR = 1.6 [1.38 - 2.00]), and risk of postpartum haemorrhage (p = 0.002;OR = 1.15 [1.05 - 1.27]). In contrast, parturients’ use of OPs was found to reduce the risk of their newborns being transferred to neonatology (p = 0.002;OR = 0.50 [0.31 - 0.79]) and dying at birth (p = 0.021;OR = 0.19 [0.03 - 0.94]). Conclusion: The use of OPs is widespread in Parakou. Several factors were associated with it. This use had a protective effect on newborns. This study shows the need to determine the active ingredients of these OPs and emphasise a safer use of them.
文摘Introduction: The bacteriology-virology laboratory of the teaching university hospital of Brazzaville, was equipped with a real-time PCR device like Miniopticon (Biorad? , France). The aim of this work was to do an evaluation of the HIV viral load activity, with a view to proposing some recommendations. Material and methods: Retrospective study, January 2013 to March 2015, in patients on first line ARV three-therapy, pre-inclusion therapy checkup in HIV positive patients, but again screening after sexual abuse in women or accident of exposure (AES). A blood sample on EDTA tube was made and RNA extraction with Qiagen kit. Ultrasensitive HIV-RNA quantification was performed using the Generic HIV real-time PCR assay (Biocentric?, Bandol, France). Results: 126 patients were included. The mean age was 37.63 years +/- 10.43 years, sex ratio F/H = 2.3. The HIV viral load was detectable in 94 cases (74.6%). Concerning patients with detectable viral load (copies/ml): 403 to 996 in 35 cases (37.23%), 1411 to 1812 in 41 cases (43.62%) and >1814 in 5 cases (5.32%) (therapeutic failure). Conclusion: This work reports success in the setting up of the molecular biology unit. Procedures that implement information and education actions on the risks associated with AES must be disclosed.
