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低出生体重青少年精神症状与精神疾病的研究
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作者 Indredavik M.s. Vik T. +1 位作者 heyerdahl s. 张振 《世界核心医学期刊文摘(儿科学分册)》 2005年第2期25-25,共1页
目的:评估与低出生体重相关的精神症状和精神疾病的发生率。试验分组:从研究总体中随机抽取14岁儿童组成研究样本,进行跟踪随访。56例极低出生体重儿被作为VLBW组,其出生体重≤1500g;60例小于胎龄的青少年被作为SGA组,其出生体重小于正... 目的:评估与低出生体重相关的精神症状和精神疾病的发生率。试验分组:从研究总体中随机抽取14岁儿童组成研究样本,进行跟踪随访。56例极低出生体重儿被作为VLBW组,其出生体重≤1500g;60例小于胎龄的青少年被作为SGA组,其出生体重小于正常足月产儿第10百分位数; 展开更多
关键词 精神疾病 足月产 极低出生体重儿 百分位数 儿童精神障碍 孤独症 ADHD 注意缺陷 评价量表 评定量表
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先天性甲状腺功能减退症:大剂量的甲状腺素对成年后的记忆、注意力和行为无显著影响
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作者 Oerbeck B. sundet K. +2 位作者 Kase B.F. heyerdahl s. 宁亮 《世界核心医学期刊文摘(儿科学分册)》 2005年第9期14-15,共2页
Background: In congenital hypothyroidism (CH) it has been questioned whether high dose thyroxine replacement therapy has detrimental effects on memory, attention, and behaviour. Aims: To describe memory, attention, an... Background: In congenital hypothyroidism (CH) it has been questioned whether high dose thyroxine replacement therapy has detrimental effects on memory, attention, and behaviour. Aims: To describe memory, attention, and behaviour problemsin young adults with CH, and to study possible negative effects of high dose thyroxine replacement therapy. Methods: Acohort based follow up study of 49 young adults (mean age 20 years)-with early treated CH, and sibling controls (n = 41). Results: Controlled for age and sex, the CH group attained significantly lower scores than sibling controls on some tests of memory (Wechsler Logical Memory part II: 12.9 versus 17.8; difference 5.2, 95% CI 3.6 to 6.8) and attention (Wechsler Freedom From Distractibility factor: 95.6 versus 104.8; difference 9.9, 95% CI 6.4 to 13.4). They rated themselves with more behaviour problems than did sibling controls (52.7 versus 44.7; difference -7.6, 95% CI -11.2 to -4.0) on the Achenbach Self Report. A high thyroxine starting dose, high serum thyroxine treatment levels during the first six childhood years, and high levels at assessment had no adverse effects on outcome measures at age 20. On the contrary, the results suggest better outcome with higher childhood treatment levels. Conclusions: Long term outcome revealed deficits in some aspects of memory, attention, and behaviour in young adults with CH relative to sibling controls. No adverse effects of high dose thyroxine therapy were found on measures of memory, attention, and behaviour problems. 展开更多
关键词 同胞对照 甲状腺功能减低 激素替代治疗 分散因子 诊断类 随访研究 自查报告 童期
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先天性甲状腺功能减退:大剂量甲状腺素治疗对成人的记忆、注意力和行为无不良影响
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作者 Oerbeck B. sundet K. +2 位作者 Kase B. F. heyerdahl s. 贺莉 《世界核心医学期刊文摘(儿科学分册)》 2005年第6期11-12,共2页
Background: In congenital hypothyroidism (CH) it has been questioned whether high dose thyroxine replacement therapy has detrimental effects on memory, attention, and behaviour. Aims: To describe memory, attention, an... Background: In congenital hypothyroidism (CH) it has been questioned whether high dose thyroxine replacement therapy has detrimental effects on memory, attention, and behaviour. Aims: To describe memory, attention, and behaviour problems in young adults with CH, and to study possible negative effects of high dose thyroxine replacement therapy. Methods: Acohort based follow up study of 49 young adults (mean age 20 years)-with early treated CH, and sibling controls (n = 41). Results: Controlled for age and sex, the CH group attained significantly lower scores than sibling controls on some tests of memory (Wechsler Logical Memory part II: 12.9 versus 17.8; difference 5.2, 95%CI 3.6 to 6.8) and attention (Wechsler Freedom From Distractibility factor: 95.6 versus 104.8; difference 9.9, 95%CI 6.4 to 13.4). They rated themselves with more behaviour problems than did sibling controls (52.7 versus 44.7; difference -7.6, 95%CI -11.2 to -4.0) on the Achenbach Self Report. A high thyroxine starting dose, high serum thyroxine treatment levels during the first six childhood years, and high levels at assessment had no adverse effects on outcome measures at age 20. On the contrary, the results suggest better outcome with higher childhood treatment levels. Conclusions: Long term outcome revealed deficits in some aspects of memory, attention, and behaviour in young adults with CH relative to sibling controls. No adverse effects of high dose thyroxine therapy were found on measures of memory, attention, and behaviour problems. 展开更多
关键词 甲状腺功能减退 同胞对照
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