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A potential new tool to enhance translational success rate in stroke research by backcrossing techniques in transgenic mice
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作者 Takayuki Nakagomi hideaki nishie +1 位作者 Toshinori Sawano Akiko Nakano-Doi 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第1期107-108,共2页
Ischemic stroke is a leading disease of the central nervous system,frequently coupled to severe damage and dysfunction in patients.Animal models mimicking human stroke provide useful tools for studying the pathomechan... Ischemic stroke is a leading disease of the central nervous system,frequently coupled to severe damage and dysfunction in patients.Animal models mimicking human stroke provide useful tools for studying the pathomechanisms(e.g.,inflammation,neuroprotection,and neural regeneration),the treatment efficiency of various materials(e.g.,bioactive molecules or drugs),and transplantation usefulness by various cell types[e.g.,neural stem/progenitor cells(NSPCs),and mesenchymal or hematopoietic stem cells]under ischemic stroke. 展开更多
关键词 INFLAMMATION damage NEURAL
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