To report the occurrence of ocular surface squamous neoplasia (OSSN) in a patient with Papillon-Lefevre syndrome. Interventional case report. A 14- year- old boy presented with a progressively growing limbal lesion in...To report the occurrence of ocular surface squamous neoplasia (OSSN) in a patient with Papillon-Lefevre syndrome. Interventional case report. A 14- year- old boy presented with a progressively growing limbal lesion in the right eye for 2 months. He had associated erythematous scaly lesions on the elbows, knees, and feet with periodontosis suggestive of Papillon-Lefevre syndrome. An excision biopsy of the limbal tumor and a skin biopsy was performed. The limbal tumor showed features of carcinoma in situ with clear margins. The skin biopsy showed epidermal hyperplasia and hyperkeratosis with perivascular infiltrates, consistent with Papillon-Lefevre syndrome. Ocular surface squamous neoplasia may occur in patients with Papillon-Lefevre syndrome, an association that to the best of our knowledge has not been previously reported.展开更多
PURPOSE: To report a novel, nonsurgical method of management of orbito-palpebral cyst associated with congenital microphthalmos. DESIGN: Interventional case series. METHODS: Two patients with orbito-palpebral cyst wer...PURPOSE: To report a novel, nonsurgical method of management of orbito-palpebral cyst associated with congenital microphthalmos. DESIGN: Interventional case series. METHODS: Two patients with orbito-palpebral cyst were included. Case 1 had bilateral orbito-palpebral cyst, whereas case 2 was unilateral. Transcutaneous cyst aspiration in both cases revealed a severely microphthalmic eye with no visual potential. Ethanolamine oleate sclerotherapywas performed immediately after cyst aspiration in both patients. RESULTS: Complete resolution of the orbito-palpebral cysts was noted within 6 weeks, and the custom prosthesiswaswell retained. CONCLUSIONS: Ethanolamine oleate sclerotherapy may be an effective minimal intervention treatment option for cosmetic rehabilitation of patients with orbito-palpebral cyst associated with congenital microphthalmos with no visual potential.展开更多
文摘To report the occurrence of ocular surface squamous neoplasia (OSSN) in a patient with Papillon-Lefevre syndrome. Interventional case report. A 14- year- old boy presented with a progressively growing limbal lesion in the right eye for 2 months. He had associated erythematous scaly lesions on the elbows, knees, and feet with periodontosis suggestive of Papillon-Lefevre syndrome. An excision biopsy of the limbal tumor and a skin biopsy was performed. The limbal tumor showed features of carcinoma in situ with clear margins. The skin biopsy showed epidermal hyperplasia and hyperkeratosis with perivascular infiltrates, consistent with Papillon-Lefevre syndrome. Ocular surface squamous neoplasia may occur in patients with Papillon-Lefevre syndrome, an association that to the best of our knowledge has not been previously reported.
文摘PURPOSE: To report a novel, nonsurgical method of management of orbito-palpebral cyst associated with congenital microphthalmos. DESIGN: Interventional case series. METHODS: Two patients with orbito-palpebral cyst were included. Case 1 had bilateral orbito-palpebral cyst, whereas case 2 was unilateral. Transcutaneous cyst aspiration in both cases revealed a severely microphthalmic eye with no visual potential. Ethanolamine oleate sclerotherapywas performed immediately after cyst aspiration in both patients. RESULTS: Complete resolution of the orbito-palpebral cysts was noted within 6 weeks, and the custom prosthesiswaswell retained. CONCLUSIONS: Ethanolamine oleate sclerotherapy may be an effective minimal intervention treatment option for cosmetic rehabilitation of patients with orbito-palpebral cyst associated with congenital microphthalmos with no visual potential.